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Grado en Medicina

Orientadores: Artemis Maria Francelin Sanches Moroni, Hermes Renato Hildebrand Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Artes Resumo: Este trabalho apresenta um estudo sobre a multisemiose e a interatividade na web arte. Neste estudo observamos os usos desses conceitos em algumas obras brasileiras concebidas especificamente para a internet. O corpo da dissertação possui a seguinte estrutura: primeiramente, refletimos sobre como a descentralização da produção e distribuição de conteúdos na internet trouxe novas discussões para o campo das mídias e das artes, e sobre como a multisemiose e a interatividade são aspectos característicos do hipertexto relevantes neste novo contexto. Apresentamos cada um desses termos separadamente, listando as referências teóricas que utilizamos em relação a cada um deles. Em seguida refletimos sobre os usos desses conceitos em obras de web arte criadas por artistas brasileiros. Analisamos o uso da multisemiose e da interatividade na obra de web arte Imaterial, de Marília Coelho e Bruno Kurru, sob a Teoria Semiótica de Charles Peirce. Por fim, apresentamos as reflexões que desenvolvemos com base nos estudos realizados Abstract: This work presents a study about multisemiosis and interactivity in web art. In this study we observed the uses of these concepts in some brazilian artworks specifically designed for the internet. The dissertation has the following structure: first, we reflected on how the decentralization of production and distribution on the internet opens a new debate in the media and arts area, and on how multisemiosis and interactivity are important characteristics of hypertext in this new context. We presented each of these terms, listing the theoretical references that we utilized in each case. Then, we reflected about the uses of these concepts in brazilian artworks. We analyzed the usage of multisemiosis and interactivity in the artwork of web art Immaterial, designed by Marília Coelho and Bruno Kurru, through the Semiotic Theory of Charles Peirce. Finally, we show the reflections that we developed with base on our studies Mestrado Artes Visuais Mestra em Artes

Trabajo presentado al Seminario de Unidad Neurobiología Molecular y Neuropatolgía del Instituto de Neurociencias, celebrado online el 28 de septiembre de 2021.

Póster presentado en: 18th European Meeting on Supercritical Fluids. 2021, 4-6 de mayo, Burdeos (online), Olive leaves (OL) are one of the by-products generated during the pruning of olives tress and during separation process in olive processing. OL are lignocellulosic biomass with important amounts of extractives and lignin (Table 1). OL have a significant amount of phenolic compounds and other bioactive compounds such as mannitol. Mannitol is a sugar alcohol with reduced caloric value compared with other sugars with different applications in the food and pharmaceutical industries due to its functional properties. Mannitol production depends on the sorbitol market since is obtained as a by-product in the catalytic hydrogenation process of sorbitol production. Therefore, alternative process to obtain mannitol from natural sources avoiding the use of high temperatures would be advantageous to obtain this polyol. In this work, valorization of OL was performed by subcritical water extraction in a batch pilot plant with 20 L capacity where 3 kg of the dry OL were put in contact with subcritical water at a medium temperature of 181.1  0.6 ºC. Figures 1 and 2 show the extraction curves of mannitol and some of the main polyphenols compounds identified by HPLC/DAD. By SW treatment, mannitol extraction yield was nearly 100 % after 20 min of extraction (OL has 99  1 mg mannitol/ g dry OL). The main PC extracted by SW was oleuropein nearly 1.5 mg/g dry OL, but also verbascoside and luteolin-7-glucoside. TPC of SW extracts was 33 mg of gallic acid equivalent/g dry OL., JCyL and ERDF for financial support of projects BU301P18 and BU050P20 and to Agencia Estatal de Investigación for project funding PID2019-104950RB-I00/AEI/10.13039/501100011033. To the company Hiperbaric through project BIOLIGNO (10/16/BU/0017), funded by ERDF and JCyL through ICE. To JCyL and ESF for E. Trigueros and P. Alonso-Riaño predoctoral contracts and for the contracts of D. Benito-Bedoya and D.M. Aymara-Caiza trough the YEI program.

Trabajo presentado al 19th Meeting Spanish Society of Neuroscience (SENC), celebrado en Lleida del 3 al 5 de noviembre de 2021., Lysine demethylases (KDMs) play a pivotal role in the establishment of cell fate and their loss or reduction is frequently linked to intellectual disability (ID). Our recent research underscores the relevance of ID-linked H3K4 demethylases in cell-type specific gene silencing, suggesting that the disruption of the neuronal transcriptome and chromatin organization that result from the loss of these epigenetic regulators critically contributes to ID etiopathology.

This manual is designed to support the training of primary school teachers, instructors and technicians, who want to improve their knowledge and develop activities about seismic and tsunami risk. The contents and information of this document come from researches carried out at present, and also as the continuation of other projects in which the author has participated, such as the game "Treme-Treme". POCTEP-INTERREG España-Portugal e Fundo Europeu de Desenvolvimento Regional (FEDER) info:eu-repo/semantics/publishedVersion

Trabajo presentado al 17th Meeting of the Spanish Society for Developmental Biology (SEBD), celebrado de forma virtual del 18 al 20 de noviembre de 2020.

RESUMEN: El incremento de la supervivencia y la esperanza de vida ha originado un aumento de la prevalencia de enfermedades crónicas en edades avanzadas. La demencia aún no recibe la prioridad que se merece, a pesar de que se conciba como la primera causa de discapacidad en adultos mayores y la enfermedad que genera mayor dependencia y sobrecarga tanto económica como del cuidador. El objetivo del presente trabajo de revisión fue definir el concepto de estimulación multisensorial en demencias moderadas-­‐avanzadas centrado en la intervención enfermera. Para ello, se realizó una búsqueda bibliográfica en las principales bases de datos de aquellas publicaciones con antigüedad no mayor a cinco años. Tras el análisis posterior de la bibliografía consultada, se puede afirmar que hoy por hoy, no existe tratamiento curativo para esta enfermedad. Sin embargo, las intervenciones no farmacológicas desde el rol del profesional de enfermería, están ocupando un primer plano a la hora de abarcar los síntomas conductuales, haciendo mención especial a la terapia Snoezelen o estimulación multisensorial (EMS). La finalidad de esta modalidad terapeútica es establecer una interacción entre la persona, la tarea y el entorno por medio de la activación de los diferentes sentidos primarios que ofrecen experiencias sensoriales dentro de una atmósfera de tranquilidad y relajación. ABSTRACT: An increase in the survival and longevity of species has led to an increase in the prevalence of chronic diseases in old ages. Dementia still does not receive the priority it deserves even though it is conceived as the first cause of disability in elderly people and the disease that generates greater dependency and economic overload. The objective of the present review was to define the concept of multisensory stimulation in advanced dementias focused on the nursing intervention. A bibliographic search was carried out in the main databases of those publications with an age not exceeding five years in order to do this. After the subsequent analysis of the consulted bibliography it can be affirmed that at this moment, there is no curative treatment for this disease. However, non-­‐pharmacological interventions given from the nursing role, occupy a leading role in the study of behavioral symptoms, with great emphasis in Snoezelen therapy or multisensory stimulation (EMS). The purpose of this therapy is to create an interaction between the person, his main goal and the environment by activating the different primary senses that provide sensory experiences within an atmosphere of trust and relaxation. Grado en Enfermería

This article belongs to the Special Issue Selected Papers from NUTRIMAD 2018. Diet-related risk factors and physical inactivity are among the leading risk factors for disability and are responsible for a large proportion of the burden of chronic non-communicable diseases. Food-based dietary guidelines (FBDGs) are useful tools for nutrition policies and public health strategies to promote healthier eating and physical activity. In this paper, we discuss the process followed in developing the dietary guidelines for the Spanish population by the Spanish Society of Community Nutrition (SENC) and further explain the collaboration with primary healthcare practitioners as presented in the context of the NUTRIMAD 2018 international congress of SENC. From a health in all policies approach, SENC convened a group of experts in nutrition and public health to review the evidence on diet-health, nutrient intake and food consumption in the Spanish population, as well as food preparation, determinants and impact of diet on environmental sustainability. The collaborative group drafted the document and designed the graphic icon, which was then subject to a consultation process, discussion, and qualitative evaluation. Next, a collaborative group was established to plan a dissemination strategy, involving delegates from all the primary healthcare scientific societies in Spain. A product of this collaboration was the release of an attractive, easy-to-understand publication.

Executive functions are a family of top down mental processes that directly affect the well-being, academic achievement and quality of life of people, and they are developed at an early age. Childhood education (3-6 years old) is an appropriate context to evaluate and to promote the development of those skills but, at the same time, it is necessary to provide tools so that teachers can observe and select individual activities for each student in the classroom. Some researchers have demonstrated that many activities can improve inhibition control and working memory in little children (Diamond, 2016; Traverso, Viterbori & Usai, 2015) but there are few tasks designed specifically for the different dimensions of inhibition control, and there is little research on effects using technological devices. In the TECHCAT Project, a multidisciplinary team of researchers are designing technological solutions to help observe, assess and improve self-regulation skills in a preschool context. Additionally, we consider the role of individuals, school and family factors in moderating children`s development of early self-regulation skills. We use a pre-post design (1 experimental and 2 control groups) with 180 children of 3-6 years old from a preschool in Malaga (Spain). In this paper, we show the characteristics of the experimental design (evaluated skills, standardized test, specific tasks, etc.), and we show results on the design process of the self-regulation tasks using adapted and original tasks: 15 motor inhibition tasks, 11 verbal inhibition tasks, 5 emotional inhibition tasks, and 7 delay reward tasks. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Ministerio de Ciencia y Tecnología.

La lectura a primera vista es una habilidad indispensable para los músicos, por lo que forma parte de numerosos procesos de selección tanto de estudiantes como profesionales. Sin embargo, es una tarea compleja en la que se ven envueltos procesos cognitivos de diferente índole: percepción visual, imagen auditiva y ejecución motora. El objetivo general de este estudio es conocer el proceso de enseñanza-aprendizaje de la lectura a primera vista en los Conservatorios Profesionales de Música de la Comunidad Valenciana, con fines de mejora educativa. La metodología utilizada es de naturaleza tanto cuantitativa como cualitativa, y se ha llevado a cabo a través de una revisión bibliográfica, un análisis descriptivo del currículo, una investigación mediante encuesta al profesorado y un análisis deductivo e inductivo para la creación de una propuesta didáctica. Los resultados ponen de manifiesto un bajo nivel por parte del alumnado y un cierto desconocimiento acerca del proceso de enseñanza-aprendizaje de esta habilidad por parte del profesorado. Esto podría solventarse con la aplicación de técnicas como la práctica regular y constante desde edades tempranas, la enseñanza de la lectura por patrones musicales, una evaluación enfocada a la mejora y la consideración de aspectos psicológicos.

Trabajo fin de grado. Defendido en junio de 2018. Introducción: La muerte es interpretada como un tabú en la sociedad. Hay gran interés en la atención al duelo aunque en el caso de la salud mental exista un estigma histórico. Justificación: Se propone la articulación de un proyecto de investigación para describir las características del duelo normal o patológico en pacientes de salud mental institucionalizados en centros de la Orden Hospitalaria de San Juan de Dios en España. Material y métodos: El conocimiento de las variables sociodemográficas y del proceso de duelo conllevan medidas para mejorar la atención y la calidad de vida. Resultados: Los resultados se compararán con el duelo patológico en personas sanas. Abstract: Introduction: Death is interpreted as a taboo nowadays. There is an enormous interest in the attention to the grief, although an historical stigma exist within the mental health. Justification: It is proposed an investigation project to describe normal or pathological grief characteristics in institutionalized mental health patients in the Orden Hospitalaria de San Juan de Dios centers in Spain. Material and methods: The knowledge of the sociodemographic variables and the duel process carry on policies to improve the attention and life quality. Results: The results will be compared to the pathological grief in mentally healthy people. Ordenador con navegador de Internet; Adobe Acrobat Reader 44 p. (Según el contador de la aplicación)

Accelerated life tests are frequently used to provide reliability information in a moderate period of time (weeks or months), and after that, a failure analysis is compulsory to detect the failure origins. In this paper, a failure analysis has been carried out after a temperature accelerated life test on lattice matched GaInP/Ga(In)As/Ge triple junction commercial solar cells. Solar cells were forward biased in darkness inside three climatic chambers in order to emulate the photo-generated current under nominal working conditions (a concentration level of 820 suns). After the accelerated aging test, a characterization of the resulting cells by means of quantum efficiency, dark and illumination I?V curves, electroluminescence, scanning electron microscope, energy dispersive X-ray, scanning transmission electron microscope and X-ray photoelectron spectroscopy has been carried out. Current is identified as the cause of degradation while temperature just dominates the accelerating factor of the aging test. Current promotes the front metal damage produced by the chemical evolution of the electroplating impurities together with those of the tab soldering process. Semiconductor structure does not seem to be responsible of any failure. Therefore, this kind of lattice matched GaInP/Ga(In)As/Ge triple junction solar cells, that as of 2016, are the workhorse of CPV technology, exhibits as a very robust device if the front metal connection is properly accomplished.

Apoyándonos en un caso seleccionado y la revisión de la bibliografía más reciente sobre los Trastornos disociativos y las Psicosis en la infancia y la adolescencia y las alteraciones sensoperceptivas propias del desarrollo, se analizan detenidamente las características de dichas categorías clínicas y las dificultades a la hora de realizar el diagnóstico diferencial. Se extraen finalmente una serie de conclusiones orientadas a realizar un diagnóstico correcto debido a la importancia de una atención precoz e individualizada y a la disparidad del pronóstico en cada una de las condiciones citadas., Grado en Medicina

The aim of this paper is to present the results of a review of Hispanic literature about continuous improvement. A rigorous review of papers included in the Dialnet data base was conducted, combining both qualitative and quantitative methods. The main results show that continuous improvement is an important field in Hispanic output although certain topics should be delved into more deeply. General knowledge journals aimed at practitioners are those that tend to publish papers related to continuous improvement, thus highlighting the relevance of the topic for practitioners. The paper offers two main contributions. First, it is novel research not been previously done in the Hispanic context. Secondly, it clarifies and complements the conclusions drawn by international reviews according to which continuous improvement seemed to be scarcely addressed in Hispanic output. El objetivo de este trabajo es realizar una revisión del campo de la Mejora Continua en la literatura. Para ello se realiza una revisión rigurosa tanto con métodos cualitativos como cuantitativos a partir de los trabajos recogidos en la base de datos Dialnet. Los principales resultados muestran que la mejora continua es un campo importante en la literatura hispana, aunque debe potenciarse en ciertas temáticas. También se detectó una clara orientación divulgativa del tema resaltando así la importancia de la mejora continua para los profesionales del sector. El trabajo tiene dos aportaciones principales. En primer lugar, es un estudio novedoso que no se había realizado previamente en la literatura hispana. Y, en segundo lugar, matiza y complementa las conclusiones obtenidas por revisiones internacionales según las cuales la mejora continua parecía no estar desarrollada en la literatura hispana.

En la primera epopeya de la Historia, la de Gilgamesh, con más de 4000 años de antigüedad, dos héroes, Gilgamesh y Enkidú miden sus fuerzas en una plaza. Ante el pueblo entran como rivales y salen como amigos, y juntos se aventuran para defender la ciudad. Ya entonces las ciudades ofrecían espacio público para resolver los problemas de los ciudadanos. A lo largo de la historia distintos espacios urbanos han tenido un papel importante para recoger las voces que expresaban los deseos y problemas de los hombres: teatros, anfiteatros, coliseos,… Todos ellos han albergado emociones, risas, preocupaciones, catarsis,… El rugido de la voz colectiva, como el de un organismo vivo que se escucha a sí mismo y al escucharse toma conciencia y fuerza, es un fenómeno que estamos viviendo intensamente en los últimos tiempos. Las plazas siguen vivas, muy vivas. In the first epic story, the poem of Gilgamesh which is more than 4000 years old, two heroes, Gilgamesh and Enkidu measure their own strengths in a square. In front of the people’s eyes, they get into the square like rivals and get out like friends, and together they´ll venture to defend the city. Already at that time the cities offered already public space, in particular squares to solve the problems of citizens. Throughout history different urban spaces have had an important role to collect the voices expressing people’s desires and problems: theaters, amphitheaters, arenas,… All of them have hosted emotions, laughter, worries, catharsis,... The roaring of the collective voice, like that of a living organism that listens to himself, and while doing so, it becomes aware and gains strength. That is a phenomenon we are living intensely in recent times. Squares are still alive, pretty much alive. Sin financiación No data 2014

The Tcra enhancer (E¿) is essential for pre-TCR-mediated activation of germline transcription and V(D)J recombination. E¿ is considered an archetypical enhanceosome that acts through the functional synergy and cooperative binding of multiple transcription factors. Based on dimethylsulfate genomic footprinting experiments, there has been a long-standing paradox regarding E¿ activation in the absence of differences in enhancer occupancy. Our data provide the molecular mechanism of E¿ activation and an explanation of this paradox. We found that germline transcriptional activation of Tcra is dependent on constant phospholipase C¿, as well as calcineurin- and MAPK/ERK-mediated signaling, indicating that inducible transcription factors are crucially involved. NFAT, AP-1, and early growth response factor 1, together with CREB-binding protein/p300 coactivators, bind to E¿ as part of an active enhanceosome assembled during pre-TCR signaling. We favor a scenario in which the binding of lymphoid-restricted and constitutive transcription factors to E¿ prior to its activation forms a regulatory scaffold to recruit factors induced by pre-TCR signaling. Thus, the combinatorial assembly of tissue- and signal-specific transcription factors dictates the E¿ function. This mechanism for enhancer activation may represent a general paradigm in tissue-restricted and stimulus-responsive gene regulation.

In this contribution, angle-resolved X-ray photoelectron spectroscopy is used to explore the extension and nature of a GaAs/GaInP heterointerface. This bilayer structure constitutes a very common interface in a multilayered III-V solar cell. Our results show a wide indium penetration into the GaAs layer, while phosphorous diffusion is much less important. The physico-chemical nature of such interface and its depth could deleteriously impact the solar cell performance. Our results probe the formation of spurious phases which may profoundly affect the interface behavior.

El proyecto SICA2, presentado por Beatriz Barros y Miguel Ángel Aguirre, de la Consejería de Economía, Innovación y Ciencia de la Junta de Andalucía, supone una innovadora extensión del concepto de CRIS universitario a un ámbito regional para el conjunto de las universidades andaluzas. El sistema de recogida y validación de la información científica en tiempo real se basa en una primera fase SICA que organiza la investigación en unidades mínimas o 'Grupos PAIDI' y que ya implementó el estándar CVN para las nueve universidades andaluzas que forman parte del proyecto. Esta segunda fase de integración tiene además prevista su prolongación en el repositorio institucional Reposit-AN de ámbito igualmente regional que se alimentará de los metadatos procedentes del sistema CRIS de la Junta de Andalucía y se presentará oficialmente a final de año. El projecte SICA2, presentat per Beatriz Barros i Miguel Ángel Aguirre, de la onsejería de Economía, Innovación y Ciencia de la Junta de Andalucía, suposa una innovadora extensió del concepte de CRIS universitari a un àmbit regional per al conjunt de les universitats andaluses. El sistema de recollida i validació de la informació científica en temps real es basa en una primera fase SICA que organitza la recerca en unitats mínimes o 'Grups PAIDI' i que ja va implementar l'estàndard CVN per a les nou universitats andaluses que formen part del projecte. Aquesta segona fase d'integració té a més previst prolongació en el repositori institucional Reposit-AN d'àmbit igualment regional que s'alimentarà de les metadades procedents del sistema CRIS de la Junta d'Andalusia i es presentarà oficialment a finals d'any. The project SICA2 presented by Beatriz Barros and Miguel Angel Aguirre, the Ministry of Economy, Innovation and Science Government of Andalusia, is an innovative extension of the concept of CRIS a regional university for the whole Andalusian universities. The system of collection and validation of scientific information in real time based on SICA initially organized research units minimum or 'Groups PAIDI' and has already implemented the standard CVN for nine Andalusian universities that are part of the project. This second phase of integration is also planned extension in the institutional repository Reposit-AN regional level is also fed by the CRIS system metadata from the Junta de Andalucia and will be officially presented at the end of the year.

La didáctica se suma a la era multimedia a traves de soluciones informáticas diseñadas de forma específica para cada entorno, alumno y nivel de enseñanza. La clase interactiva conecta lo académico con lo cotidiano facilitando tanto el estudio como la propia docencia

Asumimos que la matemática es una poderosa herramienta de comunicación. Consecuentemente, una buena alfabetización matemática debiera permitirnos analizar y comprender situaciones, organizar la información, describir fenómenos, generalizar procedimientos,… Estas capacidades son objetivos en todas las propuestas curriculares y como tal deben ser objeto de trabajo escolar desde los primeros niveles de enseñanza. Además, estas capacidades constituyen referencias básicas en el primer paso necesario para la resolución de problemas y para tomar decisiones ante los problemas de nuestra realidad. En este trabajo mostramos algunas situaciones cotidianas que debieran hacernos reflexionar sobre la manera en la que abordamos la tarea matemática en la enseñanza obligatoria.

The quasi-3D models based on distributed circuit units are a powerful tool to analyse the performance of a solar cell from the point of view of its electrical behavior. Quite accurate models have been developed in the past that reproduce the experimental data of single-junction solar cells very closely. These models help in the determination of the origin of the peculiarities of the dark and one sun or high concentration experimental I-V curves. They also allow the design of the front grid, the analysis of the impact of the electrical parameters of the solar cell on the performance of the final device, etc. In this work, these models are used to study the effect of non-uniform profiles, generated by the concentrator optics, on the performance of a concentrator solar cell. The design of the front grid is then optimized to minimize the losses introduced by the light distribution, even taking into account the effect of the tracking system misalignment. As an introductory application example of multijunction solar cells analysis with this kind of modeling, the effect of the chromatic aberration on a double junction solar cell is presented.

Resumen tomado de la publicación. Artículo seleccionado de SINTICE (Simposio Nacional de las Tecnologías de la Información y las Comunicaciones en la Educación), VI Congreso Nacional de Informática Educativa (Granada 2005), extendido y revisado para su publicación en IE Comunicaciones. Este artículo es una versión revisada y extendida del artículo presentado en el CEDI (Congreso Español de Informática) 2005 de Granada. El trabajo relatado en este artículo ha sido desarrollado dentro del proyecto europeo COLDEX (IST-2001-32327) y continuará desarrollándose dentro del marco que aporta el proyecto nacional ENLACE (TIN 2004-04232) Se presenta una solución basada en servicios web para ofrecer una distribución de contenidos y/o metadatos en repositorios de objetos de aprendizaje. De esta manera se favorece el intercambio de conocimiento dentro de comunidades de aprendizaje. Partiendo del análisis de las necesidades de una comunidad para compartir recursos generados en distintos escenarios temáticos científico-técnicos, se propone una solución que cumple sus requisitos pedagógicos. Se discuten las distintas opciones tecnológicas disponibles y se presenta el diseño realizado, que se caracteriza además por ofrecer interoperabilidad y flexibilidad para adaptar la configuración a diferentes situaciones. País Vasco Universitat de les Illes Balears. Redined Balears; Edifici Guillem Cifre de Colonya. Ctra. de Valldemossa, Km 7,5; 07122 Palma de Mallorca; +34971172792; +34971173190; redined.balears@uib.es ESP

This paper presents some of drawings made by the Guatemalan artist Antonio Tejada Fonseca when working for the Carnegie Institution archaeological missions in the Past Century Forties. More specifically, we show and comment here the images of a number of ceramics recovered from the excavations performed by Alfred Kidder and Edwin Shook at the finca El Paraíso, Quetzaltenango (Guatemala).

La comprensión lectora es una capacidad fundamental en la adquisición de conocimiento. Tal es su relevancia que se incide en el entrenamiento de esta competencia, así como su evaluación desde los primeros niveles educativos. Debido a esto, existen distintas evaluaciones de diferentes instituciones tanto europeas como españolas para recopilar información sobre el nivel de comprensión lectora de los estudiantes. En este Trabajo Fin de Grado se ha implementado una herramienta software que permita llevar a cabo un an´alisis de la comprensión lectora de los alumnos. Esta herramienta se ha integrado en el sistema web Siette. En la herramienta implementada, la comprensión lectora se evalúa utilizando mapas conceptuales. En un primer paso, el profesor crea un mapa conceptual que representa las principales ideas y relaciones de un texto dado. Posteriormente, se pide al alumno que realice un mapa conceptual del texto del ejercicio. Finalmente, ambos mapas son comparados para la corrección del ejercicio y evaluación del alumno. Dicha corrección se realiza mediante la llamada evaluación automática a partir de unos indicadores calculados a partir del mapa conceptual creado por el alumno

Foi concebido para apoiar a formação de professores, monitores e técnicos da área educativa do 1º Ciclo do Ensino Básico (CEB), que queiram melhorar os seus conhecimentos e desenvolver atividades sobre o risco sísmico e de tsunami. Os conteúdos e informação contidos neste documento surgem de novas pesquisas agora realizadas, mas também na continuação de outros projectos em que a autora participou, designadamente o jogo sério "Treme-Treme". PERSISTAH, Projectos de Escolas Resilientes aos SIsmos no Território do Algarve e de Huelva (0313_PERSISTAH_5_P; Financiado pela Comissão Europeia através do programa EP – INTERREG VA Espanha Portugal (POCTEP) info:eu-repo/semantics/publishedVersion

Las funciones ejecutivas son unas capacidades psicológicas de alta importancia para el desarrollo sano de los niños, ya que su mal desarrollo está relacionado con determinados problemas como el trastorno de déficit de atención. En este TFG está relacionado las funciones ejecutivas, poniendo énfasis en la atención. A partir del entendimiento de como ésta funciona, se ha trabajado en el desarrollo juegos serios para entrenar la atención con tareas como “busca las diferencias”, “encuentra elementos en la escena””. Estos juegos están, destinados a enriquecer las habilidades cognitivas de niños de infantil (de 3 a 5 años) y monitorizar dichas actividades. Los juegos se desarrollan en JavaScript y se integran en el sistema de evaluación automática Siette para evaluar y monitorizar el proceso de aprendizaje de los usuarios. En paralelo se ha desarrollado un sistema de registro de eventos de modo que guardaremos en un log todas las pulsaciones realizadas por un niño para que psicólogos y educadores puedan analizar el comportamiento en profundidad. Este log se almacenará en un fichero alojado en un servidor diferente de siette, usando un software de servidor implementado para tal propósito en este TFG. Todo el software se ha desarrollado siguiendo una metodología ágil y ha sido probado y evaluado con niños de educación infantil con tablets conectados a Internet.

Solar photovoltaic technologies are well known in the sustainable energy field, however, there are more technologies than the ones most people know. Crystalline Silicon is by far the most popular technology, although there are other interesting technologies with other features in the market, like CIGS and concentration III-V Multijunction cells. The range of application of solar photovoltaics is also very broad, where residential applications have become an interesting option to generate and consume energy, enhanced due to the latest regulation changes in Spain. That is why; a comparison of three photovoltaic technologies by dimensioning a block of buildings has been performed. In order to compare the three selected technologies, a first theoretical approach has been performed: looking at market shares, prices in the market, efficiencies and other technological aspects of each technology. Secondly, a practical simulation has been carried out. A real location has been selected and then, with the help of the software SAM, each technology has been simulated. The practical simulations back up the theoretical comparison between the three technologies. Compared to Monocrystalline Silicon, CIGS has proved to be a cheaper but less efficient option with a more flexible application, while concentration III-V Multijunction cells, a more expensive option with an outstanding efficiency. Ingeniería de la Energía

Melanomas are tumors originating from melanocytes and tend to show early metastasis secondary to the loss of cellular adhesion in the primary tumor, resulting in high mortality rates. Cancer-specific active immunotherapy is an experimental form of treatment that stimulates the immune system to recognize antigens on the surface of cancer cells. Current experimental approaches in immunotherapy include vaccines, biochemotherapy, and the transfer of adoptive T cells and dendritic cells. Several types of vaccines, including peptide, viral, and dendritic cell vaccines, are currently under investigation for the treatment of melanoma. These treatments have the same goal as drugs that are already used to stimulate the proliferation of T lymphocytes in order to destroy tumor cells; however, immunotherapies aim to selectively attack the tumor cells of each patient. In this comprehensive review, we describe recent advancements in the development of immunotherapies for melanoma, with a specific focus on the identification of neoantigens for the prediction of their elicited immune responses. This review is expected to provide important insights into the future of immunotherapy for melanoma.