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Fused indolizidines and quinolizidines are important skeletons in a variety of natural products and pharmacologically important compounds. A one-pot tandem route from amide to fused indolizidines and quinolizidines is disclosed. This method is conducted in mild conditions and shows well tolerance of functional groups. It is also easy to be scaled up to gram scale and can be applied smoothly to the total synthesis of alkaloids such as (±)-crispine A, (±)-xylopinine, (±)-desbromoarborescidine A, (±)-harmicine and other bioactive substances.

Testbed is an important tool for control strategies research of hybrid electric vehicle(HEV). The paper presents an dynamic testbed design for single shaft parallel HEV powertrain. The testbed uses an AC dynamometer and the monitoring computer system is developed on LABVIEW virtual instrument platform. The multi-energy management system uses AutoBox, a dSPACE rapid prototyping platform, can make HEV powertrain work under the ECE drive cycles based on MATLAB/Simulink model. ControlDesk, an experiment software, is used to monitor and change control parameters on-line. Many HEV powertrain tests are done and the results show that the testbed system has the ability to research HEV control strategies.