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1. AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation

Author

Bousquet, Jean, Barbara, Cristina, Bateman, E. D., Bel, E. H., Bewick, M., Chavannes, Niels H., Cruz, A. A., Haahtela, T., Hellings, P. W., Khaltaev, N., Carlsen, K. Lodrup, Muraro, A., Cordeiro, C. R., Rosado-Pinto, J., Samolinski, B., Strandberg, T., Valiulis, A., Yorgancioglu, A., Zuberbier, T., Adcock, I. M., Addis, A., Agache, I., Agusti, A., Alonso, A., Annesi-Maesano, I., Anto, Josep M., Bachert, C., Baena-Cagnani, C. E., Bai, C., Baigenzhin, A. K., Barnes, P. J., Beck, L., Bedbrook, Anna, Benezet, O., Bennoor, K. S., Benson, M., Bernabeu-Wittel, M., Bindslev-Jensen, C., Blain, Hubert, Blasi, F., Bonini, M., Bonini, S., Boulet, L. P., Bourdin, Arnaud, Bourret, Rodolphe, Brightling, C. E., Briggs, A. H., Brozek, J. L., Buhl, R., Bush, A., Caimmi, D. P., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Camuzat, Thierry, Canonica, G. W., Carlsen, K. H., Casale, T. B., Cazzola, M., A.M, Cepeda Sarabia, Cesario, A., Chen, Y. Z., Chkhartishvili, E., Chiron, R., Chuchalin, Alexander G., Chung, K. F., Cox, L., Crooks, George, Custovic, Adnan, Dahl, R., Dahlen, S. E., Blay, F. De, Dedeu, Antoni, Deleanu, D., Demoly, Pascal, Devillier, P., Didier, A., Dinh-Xuan, A. T., Djukanovic, R., Dokic, D., Douagui, H. B., Dubakiene, R., Eglin, S., Elliot, F., Emuzyte, R., Fabbri, Leonardo M., Fink-Wagner, A., Fletcher, M., Fokkens, W. J., Fonseca, J. A., Franco, A., Frith, P., Furber, A., Gaga, M., Gamkrelidze, A., Garcia-Aymerich, Judith, Gonzalez-Diaz, S. N., Gouzi, Fares, Garces, J., Guzmán, M. A., Harrison, D., Hayot, M., Heaney, L. G., Heinrich, J., Hooper, J., Humbert, M., Hyland, M. E., Iaccarino, G., Jakovenko, D., Jardim, J. R., Jeandel, Claude, Jenkins, C., Johnston, S. L., Jonquet, Olivier, Joos, G., Jung, K. S., Kalayci, O., Karunanithi, S., Keil, T., Kolek, V., Kowalski, M. L., Kull, I., Kuna, P., Kvedariene, V., Le, Tuyen D., Louis, R., MacNee, W., Mair, A., Manning, P. J., Keenoy, M. E. Manuel, Majer, I., Masjedi, M. R., Melén, E., Gomes, Elisabete Melo, Menzies-Gow, A., Mercier, G., Mercier, Jacques, Michel, J. P., Miculinic, N., Mihaltan, F., Milenkovic, B., Molimard, M., Momas, I., Montilla-Santana, A., Almeida, M. Morais, Morgan, M., N'Diaye, M., Nafti, S., Nekam, K., Neou, A., Nicod, L., O'Hehir, R. E., Ohta, K., Paggiaro, P. L., Palkonen, S., Palmer, S., Papadopoulos, N. G., Papi, A., Passalacqua, G., Pavord, I., Pedersen, S., Pigearias, B., Plavec, D., Postma, D. S., Price, D., Rabe, K. F., Radier-Pontal, F., Redon, Josep, Rennard, S., Roberts, J., Robine, J. M., Roca, J., Roche, N., Rodenas, F., Roggeri, A., Rolland, C., Ryan, D., Sanchez-Borges, M., Schunemann, H. J., Sheikh, A., Shields, K. M., Siafakas, N., Sibille, Y., Similowski, T., Small, I., Sola-Morales, O., Sooronbaev, T., Stelmach, R., Sterk, P. J., Stiris, T., Sud, P., Tellier, V., To, T., Todo-Bom, A., Triggiani, M., Valenta, R., Valero, A. L., Valovirta, E., Vandenplas, O., Ganse, E. Van, Vasankari, T., Vestbo, J., Vezzani, G., Viegi, Giovanni, Visier, L., Vogelmeier, C., Vontetsianos, T., Wagstaff, R., Wallaert, B., Wahn, U., Whalley, B., Wickman, M., Williams, D. M., Wilson, N., Yawn, B. P., Yiallouros, Panayiotis K., Yusuf, O. M., Zar, H. J., Zhong, N., Zidarn, M., Yiallouros, Panayiotis K. [0000-0002-8339-9285], Custovic, Adnan [0000-0001-5218-7071], Bousquet, Jean, Barbara, Cristina, Bateman, Eric, Bel, Elisabeth, Bewick, Mike, Chavannes, Niels H., Cruz, Alvaro A., Haahtela, Tari, Hellings, Peter W., Khaltaev, Nikolai, Carlsen, Karin Lodrup, Muraro, Antonella, Cordeiro, Carlos Robalo, Rosado Pinto, Jose, Samolinski, Boleslaw, Strandberg, Timo, Valiulis, Aruna, Yorgancioglu, Arzu, Zuberbier, Torsten, Adcock, I., Addis, A., Agache, I., Agusti, A., Alonso, A., Annesi Maesano, I., Anto, J. M., Bachert, C., Baena Cagnani, C., Bai, C., Baigenzhin, A., Barnes, P. J., Beck, L., Bedbrook, A., Benezet, O., Bennoor, K. S., Benson, M., Bernabeu Wittel, M., Bindslev Jensen, C., Blain, H., Blasi, F., Bonini, M., Bonini, Sergio, Boulet, L. P., Bourdin, A., Bourret, R., Bousquet, P. J., Brightling, C. E., Briggs, A., Brozek, J., Buhl, R., Bush, A., Caimmi, D., Calderon, M., Calverley, P., Camargos, P., Camuzat, T., Canonica, G. W., Carlsen, K. H., Casale, T. B., Cazzola, M., Cepeda Sarabia, A. M., Cesario, A., Chen, Y. Z., Chkhartishvili, E., Chiron, R., Chuchalin, A., Chung, K. F., Cox, L., Crooks, G., Crooks, M. G., Custovic, A., Dahl, R., Dahlen, S. E., De Blay, F., Dedeu, T., Deleanu, D., Demoly, P., Devillier, P., Didier, A., Dinh Xuan, A. T., Djukanovic, R., Dokic, D., Douagui, H., Dubakiene, R., Eglin, S., Elliot, F., Emuzyte, R., Fabbri, L., Fink Wagner, A., Fletcher, M., Fokkens, W. J., Fonseca, J., Franco, A., Frith, P., Furber, A., Gaga, M., Gamkrelidze, A., Garcia Aymerich, J., González Díaz, S., Gouzi, F., Garcés, J., Guzmán, M. A., Harrison, D., Hayot, M., Heaney, L., Heinrich, J., Hooper, J., Humbert, M., Hyland, M., Iaccarino, G., Jakovenko, D., Jardim, J., Jeandel, C., Jenkins, C., Johnston, S. L., Jonquet, O., Joos, G., Jung, K. S., Kalayci, O., Karunanithi, S., Keil, T., Kolek, V., Kowalski, M., Kull, I., Kuna, P., Kvedariene, V., Le, L. T., Louis, R., Macnee, W., Mair, A., Manning, P., Manuel Keenoy, M. E., Majer, I., Masjedi, M. R., Melén, E., Melo Gomes, E., Menzies Gow, A., Mercier, G., Mercier, J., Michel, J. P., Miculinic, N., Mihaltan, F., Milenkovic, B., Molimard, M., Momas, I., Montilla Santana, A., Morais Almeida, M., Morgan, M., N'Diaye, M., Nafti, S., Nekam, Null, Neou, A., Nicod, L., O'Hehir, R., Ohta, K., Paggiaro, P., Palkonen, S., Palmer, S., Papadopoulos, N. G., Papi, A., Passalacqua, G., Pavord, I., Pedersen, S., Pigearias, B., Plavec, D., Postma, D. S., Price, D., Rabe, K. F., Radier Pontal, F., Redon, J., Rennard, S., Roberts, J., Robine, J. M., Roca, J., Roche, N., Rodenas, F., Roggeri, A., Rolland, C., Ryan, D., Sanchez Borges, M., Schünemann, H. J., Sheikh, A., Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Small, I., Sola Morales, O., Sooronbaev, T., Stelmach, R., Sterk, P. J., Stiris, T., Sud, P., Tellier, V., To, T., Todo Bom, A., Triggiani, M., Valenta, R., Valero, A. L., Valovirta, E., Vandenplas, O., Van Ganse, E., Vasankari, T., Vestbo, J., Vezzani, G., Viegi, G., Visier, L., Vogelmeier, C., Vontetsianos, T., Wagstaff, R., Wallaert, B., Wahn, U., Whalley, B., Wickman, M., Williams, D., Wilson, N., Yawn, B. P., Yiallouros, P., Yusuf, O., Zar, H. J., Zhong, N., Zidarn, M., Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Pulmonology, Ear, Nose and Throat, Groningen Research Institute for Asthma and COPD (GRIAC), Bousquet, J., Barbara, C., Bateman, E., Bel, E., Bewick, M., Chavannes, N. H., Cruz, A. A., Haahtela, T., Hellings, P. W., Khaltaev, N., Carlsen, K. L., Muraro, A., Cordeiro, C. R., Rosado-Pinto, J., Samolinski, B., Strandberg, T., Valiulis, A., Yorgancioglu, A., Zuberbier, T., Baena-Cagnani, C., Bernabeu-Wittel, M., Bonini, S., Fink-Wagner, A., Gonzalez-Diaz, S., Garces, J., Guzman, M. A., Melen, E., Menzies-Gow, A., Montilla-Santana, A., Nekam, Sanchez-Borges, M., Schunemann, H. J., and Sola-Morales, O.

Subjects
Pediatrics, Aging, IMPACT, Respiratory System, GUIDELINES, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Risk Factors, Surveys and Questionnaires, PROGRAM, Surveys and Questionnaire, 030212 general & internal medicine, Respiratory system, ComputingMilieux_MISCELLANEOUS, health care economics and organizations, Respiratory Function Test, media_common, GINA STRATEGY, integumentary system, musculoskeletal, neural, and ocular physiology, respiratory system, Middle Aged, humanities, Adult, Aged, Asthma, Chronic Disease, Europe, Humans, Respiration Disorders, Respiratory Function Tests, Pulmonary and Respiratory Medicine, 3. Good health, ALLERGIC RHINITIS, CHRONIC RESPIRATORY-DISEASES, Editorial, General partnership, GA(2)LEN, Human, Chronic Obstructive, medicine.medical_specialty, UNION, Pulmonary disease, Socio-culturale, Pulmonary Disease, 03 medical and health sciences, medicine, media_common.cataloged_instance, European union, Intensive care medicine, business.industry, Risk Factor, Respiration Disorder, medicine.disease, nervous system diseases, Chronic disease, DEFINITION, 030228 respiratory system, Healthy ageing, business, SEVERE ASTHMA
Abstract

Chronic respiratory diseases (CRDs) are major non-communicable diseases (NCDs) [1, 2] that induce a significant burden. Asthma often occurs along the life cycle from early childhood, affecting 30 million children and adults under 45 years of age in Europe [3]. Chronic obstructive pulmonary disease (COPD) has an estimated annual death rate of over 3 million people globally [1, 2]. The annual direct and indirect costs in the 28 European Union (EU) countries due to COPD or asthma are estimated at 48 billion euros and 34 billion euros respectively [3]. Rhinitis occurs in over 100 million people in Europe, and indirect costs are enormous [4]. Asthma is a common risk factor for COPD [5, 6]. CRDs impact ageing and should be prevented, recognised and managed across the life cycle to promote active and healthy ageing (AHA). There is an urgent need to act globally. European Innovation Partnerships (EIPs) aim to enhance EU competitiveness and tackle societal challenges through research and innovation. To tackle the potential of ageing in the EU, the European Commission, within its Innovation Union policy, launched the EIP on AHA (between the Directorate General for Health and Food Safety (DG Santé) and Directorate General for Communications Networks, Content and Technology (DG CONNECT)) [7]. The B3 Action Plan promotes integrated care models for chronic diseases, including the use of remote monitoring. The initiative AIRWAYS-ICPs (integrated care pathways for airway diseases) [8] has been approved by the EIP on AHA as the model of chronic diseases of the B3 Action Plan. It is a Research Demonstration Project of the World Health Organization's Global Alliance against Chronic Respiratory Diseases (GARD) [1]. AIRWAYS-ICPs was initiated in 2013 by the WHO Collaborating Centre of Montpellier and the EIP on AHA Reference Site MACVIA-LR (Contre les MAladies Chroniques Pour un VIeillissement Actif en Languedoc-Roussillon, France) led by the Région Languedoc-Roussillon (France) [9]. 47 4 1028 1033

Published
2015
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2. Assessment of problematic severe asthma in children

Author

Carlsen, K. C. L., Hedlin, G., Bush, A., Wennergren, G., de Benedictis, F. M., De Jongste, J. C., Baraldi, E., Pedroletti, C., Barbato, A., Malmstrom, K., Pohunek, P., Pedersen, S., Piacentini, G. L., Middelveld, R. J. M., Carlsen, K. H., Grp, Psaci, and Pediatrics

Subjects
Pulmonary and Respiratory Medicine, Severe asthma, medicine.medical_specialty, diagnosis, Comorbidity, Severity of Illness Index, children, Treatment plan, medicine, Humans, Anti-Asthmatic Agents, Child, Intensive care medicine, Rhinitis, Asthma, business.industry, medicine.disease, Respiratory Function Tests, Clinical Practice, Treatment Outcome, Lung disease, Physical therapy, Bronchial Hyperreactivity, business
Abstract

Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients.

Published
2011
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3. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)

Author

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W. J., Togias, A., Zuberbier, T., Baena-Cagnani, C. E., Canonica, G. W., van Weel, C., Agache, I., Aït-Khaled, N., Bachert, C., Blaiss, M. S., Bonini, S., Boulet, L.-P., Bousquet, P.-J., Camargos, P., Carlsen, K.-H., Chen, Y., Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S. R., van Wijk, R Gerth, Kalayci, O., Kaliner, M. A., Kim, Y.-Y., Kowalski, M. L., Kuna, P., Le, L. T. T., Lemiere, C., Li, J., Lockey, R. F., Mavale-Manuel, S., Meltzer, E. O., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R. E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T. A., Rabe, K. F., Rosado-Pinto, J., Scadding, G. K., Simons, F. E. R., Toskala, E., Valovirta, E., van Cauwenberge, P., Wang, D.-Y., Wickman, M., Yawn, B. P., Yorgancioglu, A., Yusuf, O. M., Zar, H., Annesi-Maesano, Isabella, Bateman, E. D., Ben Kheder, A., Boakye, D. A., Bouchard, J., Burney, P., Busse, W. W., Chan-Yeung, M., Chavannes, N. H., Chuchalin, A., Dolen, W. K., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S. L., Keith, P. K., Kemp, J. P., Klossek, J.-M., Larenas-Linnemann, D., Lipworth, B., Malo, J.-L., Marshall, G. D., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M. P., Potter, P., Price, D., Stoloff, S. W., Vandenplas, O., Viegi, G., Williams, D., Renseigné, Non, Dermatology, Internal Medicine, Hôpital Arnaud de Villeneuve [CHRU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), inconnu, Inconnu, Forschungszentrum Jülich GmbH - Projektträger BEO, GmbH, Photochimie moléculaire et macromoléculaire (PMM), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Department of Dermatology, Medical School-Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], P&A Kyriakou Children's Hospital, Forschungszentrum Karlsruhe, Epidémiologie des maladies infectieuses et modélisation (ESIM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'étude des textures et application aux matériaux (LETAM), Université Paul Verlaine - Metz (UPVM)-Centre National de la Recherche Scientifique (CNRS), Université de Poitiers, Merlin Circuit Technology LTD, Bousquet J, N Khaltaev, RG van Wijk, Kalayci O, je Agache, MA Kaliner, YY Kim, Kowalski ML, Denburg J, P Kuna, Le LT, C Lemiere, KH Carlsen, Li J, Lockey RF, Manuel-S Mavale, Khaled Aït N, EO Meltzer, Mohammad Y, Mullol J, R Naclerio, Fokkens WJ, RE O'Hehir, Chen Y, K Ohta, S Ouedraogo, S Palkonen, N Papadopoulos, C Bachert, G Passalacqua, Pawankar R, TA Popov, KF Rabe, Rosado Pinto-J, Cruz AA, Togias A, GK Scadding, FE Simons, E Toskala, E Valovirta, MS Blaiss, P Van Cauwenberge, Wang DY, M Wickman, BP Yawn, Custovic A, Yorgancioglu A, OM Yusuf, T Zuberbier, H Zar, Annesi-Maesano I, ED Bateman, S Bonini, Ben Kheder A, DA Boakye, Bouchard J, R Dahl, P Burney, WW Busse, M Chan-Yeung, Chavannes NH, Baena-Cagnani CE, Chuchalin A, WK Dolen, LP Boulet, R Emuzyte, L Grouse, Demoly P, M Humbert, C Jackson, SL Johnston, Keith PK, JP Kemp, JM Klo, GW Canonica, C Weel van, Bousquet PJ, P Camargos, H Douagui, SR Durham, and Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut de Chimie du CNRS (INC)

Subjects
Rhinitis, Allergic, Perennial, MESH: Asthma, Adolescent, Global Health, World Health Organization, MESH: World Health Organization, MESH: Risk Factors, Risk Factors, MESH: Child, Effective Primary Care and Public Health [EBP 3], Prevalence, Humans, Child, ComputingMilieux_MISCELLANEOUS, MESH: Prevalence, MESH: Adolescent, MESH: Humans, MESH: Rhinitis, Allergic, Perennial, Cardiovascular diseases [NCEBP 14], Rhinitis, Allergic, Seasonal, MESH: Rhinitis, Allergic, Seasonal, Effective primary care and public health [NCEBP 7], Asthma, World Health, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH: World Health
Abstract

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes major illness and disability worldwide. Over 600 million patients from all countries, all ethnic groups and of all ages suffer from allergic rhinitis. It affects social life, sleep, school and work and its economic impact is substantial. Risk factors for allergic rhinitis are well identified. Indoor and outdoor allergens as well as occupational agents cause rhinitis and other allergic diseases. The role of indoor and outdoor pollution is probably very important, but has yet to be fully understood both for the occurrence of the disease and its manifestations. In 1999, during the Allergic Rhinitis and its Impact on Asthma (ARIA) WHO workshop, the expert panel proposed a new classification for allergic rhinitis which was subdivided into 'intermittent' or 'persistent' disease. This classification is now validated. The diagnosis of allergic rhinitis is often quite easy, but in some cases it may cause problems and many patients are still under-diagnosed, often because they do not perceive the symptoms of rhinitis as a disease impairing their social life, school and work. The management of allergic rhinitis is well established and the ARIA expert panel based its recommendations on evidence using an extensive review of the literature available up to December 1999. The statements of evidence for the development of these guidelines followed WHO rules and were based on those of Shekelle et al. A large number of papers have been published since 2000 and are extensively reviewed in the 2008 Update using the same evidence-based system. Recommendations for the management of allergic rhinitis are similar in both the ARIA workshop report and the 2008 Update. In the future, the GRADE approach will be used, but is not yet available. Another important aspect of the ARIA guidelines was to consider co-morbidities. Both allergic rhinitis and asthma are systemic inflammatory conditions and often co-exist in the same patients. In the 2008 Update, these links have been confirmed. The ARIA document is not intended to be a standard-of-care document for individual countries. It is provided as a basis for physicians, health care professionals and organizations involved in the treatment of allergic rhinitis and asthma in various countries to facilitate the development of relevant local standard-of-care documents for patients.

Published
2008
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4. Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report

Author

Bacharier, L. B., Boner, Attilio, Carlsen, K. H., Eigenmann, P. A., Frischer, T., Götz, M., Helms, P. J., Hunt, J., Liu, A., Papadopoulos, Nikolaos, Platts Mills, T., Pohunek, P., F. E. R., Valovirta, E., Wahn, U., Wildhaber, J., and European Pediatric Asthma

Subjects
Male, ddc:618, guidelines, Asthma, United States, respiratory tract diseases, Asthma/diagnosis/therapy, diagnosis, Europe, pediatric asthma, immune system diseases, monitoring, Child, Preschool, Practice Guidelines as Topic, Humans, Female, treatment, Practice Guidelines as Topic/standards, education, Child
Abstract

Asthma is the leading chronic disease among children in most industrialized countries. However, the evidence base on specific aspects of pediatric asthma, including therapeutic strategies, is limited and no recent international guidelines have focused exclusively on pediatric asthma. As a result, the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology nominated expert teams to find a consensus to serve as a guideline for clinical practice in Europe as well as in North America. This consensus report recommends strategies that include pharmacological treatment, allergen and trigger avoidance and asthma education. The report is part of the PRACTALL initiative, which is endorsed by both academies.

Published
2007

5. MeDALL (Mechanisms of the Development of ALLergy): An integrated approach from phenotypes to systems medicine,MeDALL (Mechanizmy powstawania alergii): Zintegrowane podejście - od fenotypów do medycyny systemowej

Author

Kowalski, M. L., Akdis, M., Auffray, C., Keil, T., Anto, J., Bousquet, J., Grupa Badawcza Medall, I., Haahtela, T., Cambon-Thomsen, A., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi-Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev-Jensen, C., Brunekreef, B., Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Forastiere, F., Garcia-Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Lau, S., Lodrup-Carlsen, K. C., Lopez-Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Martijn Nawijn, Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial-Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., Cauwenberge, P., Oosterhout, A. J. M., Varraso, R., Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J., and Zuberbier, T.

6. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update: In collaboration with the World Health Organization, GA(2)LEN and AllerGen | ARIA update 2008: Die allergische rhinitis und ihr einfluss auf das asthma

Author

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W., Togias, A., Zuberbier, T., Baena-Cagnani, C., Canonica, G. W., Weel, C., Agache, I., Aït-Khaled, N., Bachert, C., Blaiss, M., Bonini, S., Boulet, L. -P, Bousquet, P. -J, Camargos, P., Carlsen, K. -H, Custovic, A., Chen, Y., Dahl, R., Demoly, P., Douagui, H., Durham, S., Wijk, R. G., Kalayci, O., Kaliner, M., Kim, Y. -Y, Kowalski, M. L., Kuna, P., Lemiere, C., Tuyet Lan, L. T., Li, J., Lockey, R., Mavale, S., Meltzer, E. O., Mohammad, Y., Mullol, J., Naclerio, R., Ohehir, R., Ohta, K., Ouedraogo, S., Palkonen, S., Nikolaos Papadopoulos, Passalacqua, G., Pawankar, R., Popov, T., Rabe, K., Rosado-Pinto, J., Scadding, G., Simons, F. E. R., Toskala, E., Valovirta, E., Cauwenberge, P., Wang, D. Y., Wickman, M., Yawn, B., Yorgancioglu, A., Yusuf, O., and Zar, H.

7. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update: In collaboration with the World Health Organization, GA(2)LEN and AllerGen,ARIA update 2008: Die allergische rhinitis und ihr einfluss auf das asthma

Author

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W., Togias, A., Zuberbier, T., Baena-Cagnani, C., Canonica, G. W., Weel, C., Agache, I., Aït-Khaled, N., Bachert, C., Blaiss, M., Bonini, S., Boulet, L. -P, Bousquet, P. -J, Camargos, P., Carlsen, K. -H, Custovic, A., Chen, Y., Dahl, R., Demoly, P., Douagui, H., Durham, S., Wijk, R. G., Kalayci, O., Kaliner, M., Kim, Y. -Y, Kowalski, M. L., Kuna, P., Lemiere, C., Tuyet Lan, L. T., Li, J., Lockey, R., Mavale, S., Meltzer, E. O., Mohammad, Y., Mullol, J., Naclerio, R., Ohehir, R., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T., Rabe, K., Rosado-Pinto, J., Scadding, G., Simons, F. E. R., Toskala, E., Valovirta, E., Cauwenberge, P., Wang, D. Y., Wickman, M., Yawn, B., arzu yorgancıoglu, Yusuf, O., and Zar, H.

8. MeDALL (Mechanisms of the Development of ALLergy): An integrated approach from phenotypes to systems medicine | MeDALL (Mechanizmy powstawania alergii): Zintegrowane podejście - od fenotypów do medycyny systemowej

Author

Kowalski, M. L., Akdis, M., Auffray, C., Keil, T., Anto, J., Bousquet, J., Grupa Badawcza Medall, I., Haahtela, T., Cambon-Thomsen, A., Lambrecht, B. N., Postma, D. S., Sunyer, J., Valenta, R., Akdis, C. A., Annesi-Maesano, I., Arno, A., Bachert, C., Ballester, F., Basagana, X., Baumgartner, U., Bindslev-Jensen, C., Brunekreef, B., Carlsen, K. H., Chatzi, L., Crameri, R., Eveno, E., Francesco Forastiere, Garcia-Aymerich, J., Guerra, S., Hammad, H., Heinrich, J., Hirsch, D., Jacquemin, B., Kauffmann, F., Kerkhof, M., Kogevinas, M., Koppelman, G. H., Lau, S., Lodrup-Carlsen, K. C., Lopez-Botet, M., Lotvall, J., Lupinek, C., Maier, D., Makela, M. J., Martinez, F. D., Mestres, J., Momas, I., Nawijn, M. C., Neubauer, A., Oddie, S., Palkonen, S., Pin, I., Pison, C., Rancé, F., Reitamo, S., Rial-Sebbag, E., Salapatas, M., Siroux, V., Smagghe, D., Torrent, M., Toskala, E., Cauwenberge, P., Oosterhout, A. J. M., Varraso, R., Hertzen, L., Wickman, M., Wijmenga, C., Worm, M., Wright, J., and Zuberbier, T.

9. Asthma and dietary intake: an overview of systematic reviews

Author

André Moreira, Matteo Bonini, João Fonseca, Nikolaos G. Papadopoulos, D. Charles, Luís Delgado, Tari Haahtela, Tim Reeves, Vanessa Garcia-Larsen, Sergio Bonini, Kai-Håkon Carlsen, Ioana Agache, S. Del Giacco, Garcia Larsen, V, Del Giacco, S. R., Moreira, A., Bonini, M., Charles, D., Reeves, T., Carlsen, K. H., Haahtela, T., Bonini, Sergio, Fonseca, J., Agache, I., Papadopoulos, N. G., and Delgado, L.

Subjects
Risk, Gerontology, Pathology, medicine.medical_specialty, food intake, Mediterranean diet, Allergy, Immunology, Population, Context (language use), law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, systematic review, law, Wheeze, Odds Ratio, medicine, Humans, Immunology and Allergy, 030212 general & internal medicine, Vitamin D, education, Asthma, education.field_of_study, business.industry, Age Factors, Odds ratio, asthma, medicine.disease, Systematic review, 030228 respiratory system, 1107 Immunology, Fruit, Population Surveillance, wheeze, Dietary Supplements, medicine.symptom, business, diet
Abstract

Epidemiological research on the relationship between diet and asthma has increased in the last decade. Several components found in foods have been proposed to have a series of antioxidant, anti-allergic and anti-inflammatory properties, which can have a protective effect against asthma risk. Several literature reviews and critical appraisals have been published to summarize the existing evidence in this field. In the context of this EAACI Lifestyle and asthma Task Force, we summarize the evidence from existing systematic reviews on dietary intake and asthma, using the PRISMA guidelines. We therefore report the quality of eligible systematic reviews and summarize the results of those with an AMSTAR score >=32. The GRADE approach is used to assess the overall quality of the existing evidence. This overview is centred on systematic reviews of nutritional components provided in the diet only, as a way to establish what type of advice can be given in clinical practice and to the general population on dietary habits and asthma.

Published
2015
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10. Rhinitis and asthma in athletes: an ARIA document in collaboration with GA2LEN

Author

M. T. Ventura, Gianni Passalacqua, Vito Brusasco, S. Jaeger, J Cummiskey, Bente Klarlund Pedersen, K-H. Carlsen, Jean Bousquet, Luís Delgado, Lorenzo Corbetta, Paolo Palange, A. M. Vignola, S. Del Giacco, Costanzo Moretti, Todor A. Popov, Tari Haahtela, Matteo Bonini, G.W. Canonica, Sergio Bonini, Guido Rasi, Desiderio Passali, Bonini, Sergio, Bonini, M, Bousquet, J, Brusasco, V, Canonica, Gw, Carlsen, K. H., Corbetta, L, Cummiskey, J, Delgado, L, DEL GIACCO, Sr, Haahtela, T, Jaeger, S, Moretti, C, Palange, P, Passalacqua, G, Passali, D, Pedersen, Bk, Popov, T, Rasi, G, Ventura, Mt, and Vignola, Am

Subjects
Allergy, medicine.medical_specialty, Rhinitis, Allergic, Perennial, Sports medicine, Immunology, MEDLINE, Sports Medicine, Agency (sociology), medicine, Humans, Immunology and Allergy, Exercise, Rhinitis, Asthma, Exercise-induced asthma, High prevalence, biology, Athletes, business.industry, Rhinitis, Allergic, Seasonal, medicine.disease, biology.organism_classification, respiratory tract diseases, Family medicine, Physical therapy, business, Sports
Abstract

This consensus document is aimed at reviewing evidence that the rhinitis-asthma links have peculiar features in athletes. Beside a review of epidemological data on the high prevalence of rhinitis and asthma in athletes, the effects on intense physical exercise on the immune system and repiratory functions are discussed, with special reference to the role of allergens and pollutants. In extending the Allergic Rhinitis and its Impact on Asthma (ARIA) recommendations to athletes, the issue is addressed of adapting diagnosis and management to criteria set by the International Olympic Committee (IOC) and regulations adopted by the World Anti-Doping Agency (WADA).

Published
2006
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