Search

Fibroblast growth factor receptor-like-1 (FGFRL1) is important to cell motility and links with tumorigenic potential in various types of cancers. To investigate the biological function and underlying mechanism of FGFRL1 in rectal adenocarcinoma, we conducted this study. TCGA and Oncomine databases were used to analyze FGFRL1 expression and its association with clinical characteristics or overall survival (OS) in rectal adenocarcinoma patients. siRNA strategy was implemented to knockdown FGFRL1 expression in rectal adenocarcinoma cells. CCK8, colony formation, wound healing, and transwell assays were implemented to measure cell behaviors. qRT-PCR and western blot were utilized to identify mRNA and protein expression levels. FGFRL1 was significantly increased in rectal adenocarcinoma tissue samples, either colon or rectum. High-regulation of FGFRL1 expression induced poorer outcome of rectal adenocarcinoma patients. Downregulation of FGFRL1 inhibited the proliferation, colony formation, migration, and invasion of SW837 cells. The MAPK pathway-related proteins, phosphorylation of MEK and ERK, were also decreased after si-FGFRL1 transfection. These findings demonstrated that FGFRL1, acting as a potential inducator, may promote the progression of rectal adenocarcinoma via activating the MAPK signaling pathway.

Additional file 1. Table S1. GenBank accession numbers of Chinese rotavirus strains with G8 genotype. Table S2. Comparison of VP7 gene’s pairwise distances between Chinese G8 strains and closely related strains.

This paper develops a general and complete solution for the undrained cylindrical cavity expansion problem in non-associated Mohr-Coulomb soil under non-hydrostatic initial stress field (i.e., arbitrary K_0 values of the earth pressure coefficient), by expanding a unique and efficient graphical solution procedure recently proposed by Chen & Wang in 2022 for the special in situ stress case with K_0 = 1. The new generalized, graph-based theoretical framework contains two essential components: the geometrical analysis to track the stress path trajectory/evolution in different sectors of the deviatoric plane; and a full Lagrangian formulation of both the constitutive relationship and radial equilibrium equation to analytically determine the representative soil particle responses at the cavity surface. It is interesting to find that the cavity expansion deviatoric stress path is always composed of a series of piecewise straight lines, for all different case scenarios of K_0 being involved. The salient advantage/feature of the present general graphical approach lies in that it can deduce the cavity expansion responses in full closed form, nevertheless being free of the limitation of the intermediacy assumption for the vertical stress and of the difficulty existing in the traditional zoning method that involves cumbersome, sequential determination of distinct Mohr-Coulomb plastic regions. The analytical closed-form solutions developed herein can be regarded as a definitive one for the undrained cavity expansion problem in classical Mohr-Coulomb materials without the approximations and simplifications in previous solutions, and will be of great value for the interpretation of pressuremeter tests in cohesive-frictional soils., 37 pages with 7 figures and 1 table

Background: Gastric cancer (GC) is one of the most common malignancies, and more and more evdiences show that the pathogenesis is regulated by various miRNAs. In this study, we investigated the role of miR-875 in GC. Methods: The expression of miR-875-5p was detected in human GC specimens and cell lines by miRNA RT-PCR. The effect of miR-875-5p on GC proliferation was determined by CCK-8 proliferation assay and EDU assay. Migration and invasion were examined by transwell migration and invasion assay and wound healing assay. The interaction between miR-875-5p and its target gene USF2 was verified by a dual luciferase reporter assay. The effects of miR-875-5p in vivo were studied in xenograft nude mice models. Related proteins were detected by Western blot. Results: The results showed that miR-875-5p inhibited the proliferation, migration and invasion of gastric cancer cells in vitro, and inhibited tumorigenesis in vivo. USF2 proved to be a direct target of miR-875-5p. Knockdown of USF2 partially counteracts the effects of miR-875-5p inhibitors. Overexpression of miR-875-5p can inhibit proliferation, migration, and invasion through the TGF-β signaling pathway by down-regulation of USF2 in GC, providing a new research direction for the diagnosis and targeted therapy of GC.Conclusions: MiR-875-5p can inhibited the progression of GC by directly targeting USF2 and negatively regulating TGF-β signaling pathway. In the future, miR-875-5p is expected to be used as a potential therapeutic target for GC therapy.

We report the experimental results of magnetotransport on the single crystal ${\mathrm{MoGe}}_{2}$, which was theoretically predicated to be a topological insulator. The resistivity of ${\mathrm{MoGe}}_{2}$ exhibits a metallic behavior at zero field, while with magnetic fields applied along the $z$ axis and perpendicular to current, ${\mathrm{MoGe}}_{2}$ presents an upturn resistivity behavior and unsaturated quadratic large magnetoresistance (MR). The analysis of Hall effect shows that ${\mathrm{MoGe}}_{2}$ is a compensated semimetal with high mobilities at low temperatures, which is the origin of resistivity upturn and unsaturated large MR. As magnetic fields parallel to current, ${\mathrm{MoGe}}_{2}$ shows a weak antilocalization effect at low fields and a pronounced negative MR at higher fields, which is analogous to the picture of the Adler-Bell-Jackiw axial anomaly. Our results indicate that ${\mathrm{MoGe}}_{2}$ is a topological semimetal rather than a topological insulator, and will encourage further theoretical and experimental investigations on this compound.

This publication is part of the proceedings of the Biot-Bažant Conference on Engineering Mechanics and Physics of Porous Materials, which took place virtually on June 1-3, 2021. It contains a one-page abstract and the video of the talk that was given at the conference.

We report the transport properties of a topological insulator candidate, LiMgBi. The electric resistivity of the title compound exhibits a metal-to-semiconductor-like transition at around 160 K and tends to saturation below 50 K. At low temperatures, the magnetoresistance is up to ∼260 % at 9 T and a clear weak antilocalization effect is observed in the low magnetic-field region. The Hall measurement reveals that LiMgBi is a multiband system, where hole-type carriers (n h ∼ 1018 cm−3) play a major role in the transport process. Remarkably, LiMgBi possess a large Seebeck coefficient ∼440 μV/K) and a moderate thermal conductivity at room temperature, which indicate that LiMgBi is a promising candidate in thermoelectric applications.

The surface of TiO2 inverse opal material was modified by Liquid Phase Deposition(LPD) method, and a layer of TiO2 nanoparticles was deposited on the inverse opal framework in order to increase the specific surface area. The photo-catalytical degradation of Rhodamine B was used as the probe-reaction to investigate the photocatalysis ac- tivity of the TiO2 inverse opal membranes, and the influences of boric acid concentration of the LPD solution on surface morphology and photocatalysis activity of TiO2 inverse opal membranes were investigated. The results showed that the photocatalysis activity of TiO2 inverse opal membrane modified by LPD method was improved which was about 6 times higher than that of the unmodified TiO2 inverse opal when the boric acid concentration of PLD solution was 0.0183 g/mL.

Membrane bioreactor (MBR) is considered to be a promising technology for combine biological with filtration and many advantages over conventional activated sludge (CAS) processes. In this study, the submerged membrane bioreactor which was explored by our research group and JDL Environmental Protection Ltd. at condition of aerobic-MBR and SBR-MBR were investigated. Hydraulic characteristics of MBR by the tracer experiments showed the total dead space (Vd, %) in the MBR was 3.2%. Compared with aerobic-MBR situation, the SBR-MBR exhibited better performance of average NH4+-N, total nitrogen, and phosphorus removal efficiency 90%, 86%, 57% respectively. The content of protein was correlated to sludge activity and organic matter. The initial membrane fouling was caused by layer pollution and subsequently the extra-cellular polymeric substances (EPS) contributed.

Colorectal cancer (CRC) is the third most common cause of cancer-associated mortality worldwide. Currently, 5-fluorouracil (5-FU) remains a widely used chemotherapeutic drug in the treatment of CRC; however, 5-FU resistance during treatment has become a common problem. Livin, a member of the inhibitor of apoptosis protein family, is considered to be associated with tumor resistance to chemotherapy. In the present study, Livin-silenced cells were generated by introducing a lentivirus into HCT116 and SW620 colon cancer cell lines. Acridine orange/ethidium bromide staining was used as an indicator of cell death. Western blot analysis was performed to detect protein expression levels, and transmission electron microscopy was used to assess autophagy. The half-maximal inhibitory concentration of 5-FU in colon cancer cells was evaluated using a Cell Counting Kit-8 assay. The results of the present study confirmed that silencing Livin significantly enhanced colon cancer cell death in the presence of 5-FU, increased expression levels of various apoptosis- and autophagy-associated proteins and augmented chemotherapeutic sensitivity to 5-FU. Furthermore, the present study demonstrated that this effect may be reversed when autophagy or apoptosis was inhibited, indicating that apoptosis and autophagy were involved in this process. The protein kinase B signaling pathway and B-cell lymphoma-2 expression levels significantly decreased following Livin knockdown, suggesting they may contribute to the regulation of apoptosis and autophagy crosstalk, which caused the Livin knockdown-induced cell death observed.

Livin is a novel member of the inhibitor of apoptosis protein family, which has been identified to be expressed in various malignancies and is suggested to be associated with poor prognostic significance. However, no data are available concerning the significance of livin in mid-distal rectal cancer. In the present study, livin expression, and its association with clinicopathological characteristics and prognosis was examined in patients with mid-distal rectal cancer. Apoptotic susceptibility, invasion capacity and chemosensitivity of LoVo cells were investigated using small interfering RNA (siRNA)-mediated knockdown of livin. It was revealed that livin was highly expressed in mid-distal rectal cancer tissues compared with the normal rectal mucosal tissues. Livin expression was associated with pathological grade, extent of invasion (T stage) and extent of lymph node metastasis (N stage) of tumor, contributing to poor prognosis of mid-distal rectal cancer following surgery. The data suggest that aggressive surgery should be applied in patients with mid-distal rectal cancer with high expression of livin. It was also revealed that knockdown of livin by siRNA increased the apoptotic rate, suppressed invasion of LoVo cells, and decreased the half-maximal inhibitory concentration of oxaliplatin and 5-fluorouracil by ~50% in LoVo cells significantly compared with control groups. The data suggested that a combination of downregulation of livin and anticancer drugs may significantly decrease the toxicity of anticancer drugs. Taken together, the present study indicated that livin may be a promising target in clinical therapy of mid-distal rectal cancer.

The molecular orbitals for B4H4, B4F4, B4Cl4, B4Br4 and B4I4 have been calculated by using all-electron or effective core potential ab initio method at the self-consistent field level using basis sets with diffuse and polarization functions. The boron—boron and boron—halide (—hydrogen) distances of these cage compounds are optimized with three kinds of basis sets constrained to a tetrahedral symmetry. According to the localization scheme of Boys, four three-centered two-electron (3c2e) B—B—B bonds localized on each of the faces of the B4 tetrahedron are derived for B4X4 clusters. The HOMO-LUMO energy gaps, atomization energies and Mulliken overlap populations of these compounds indicate that the stabilities of the clusters decrease in the sequence of B4F4 > B4Cl4, B4H4 > B4Br4 > B4I4.

It has been generally accepted that internal diffusion in catalysts has become increasingly important for Residue Fluid Catalytic Cracking (RFCC) because of the large molecules of residue, high reaction temperature and the short contact time between the catalysts and the residue during the catalytic process. The creation of mesopores and macropores inside RFCC catalysts is considered as an effective approach to improve the accessibility and catalyst performance. In this article, polystyrene particles were used as template to introduce macropores to the RFCC catalysts. The pore structure was characterized by SEM and N2 adsorption. The catalytic cracking performance of the RFCC catalysts with macroporous structure was tested in a fixed-bed tubular reactor using Daqing atmospheric residue as feed. The macroporous catalysts exhibit better catalytic performance, higher conversion, and higher yield of light oil than the controller catalyst.

Based on the theory of elastic wave propagation in saturated soil subgrade established by the author of this paper, the axisymmetric vertical vibration of a rigid circular foundation resting on partially saturated soil subgrade which is composed of a dry elastic layer and a saturated substratum is studied. The analysis relied on the use of integral transform techniques and a pair of dual integral equations governing the vertical vibration of the rigid foundation is listed under the consideration of mixed boundary-value condition. The results are reduced to the case for saturated half-space. The set of dual integral equations are reduced to a Fredholm integral equation of the second kind and solved by numerical procedures. Numerical examples are given at the end of the paper and plots of the dynamic compliance coefficient Cv versus the dimensionless frequency a0 are presented.

The purpose of the study was to explore the significance of FGFR4 protein expression in colorectal cancer. Immunohistochemistry showed 46.8% (148/316) tumors positive for FGFR4 and 7.3% (23/316) for adjacent normal specimens. FGFR4 positivity was correlated with shortened disease free survival (DFS) and overall survival (OS). Multivariate analysis revealed that FGFR4 was an independent prognostic factor. FGFR4 silencing markedly reduced the migration and invasion capacity of colorectal cancer cell lines. These results suggest FGFR4 is a potential prognostic and therapeutic marker for colorectal cancer.

The electrochemical quartz crystal microbalance (EQCM) was applied to study the electrochemical behaviors of polycrystalline Au in sulfuric acid solution. The large mass change observed in the doublelayer region was attributed to the partly discharged adsorption of sulfate anions with the co-adsorption of H2O. According to the observed EQCM frequency response, the formation mechanism of surface oxide was reasonably postulated, in which the roles of the adsorbed anions and the co-adsorbed H2O were particularly emphasized.

The nanosized Ca3Co2O6 powder was synthesized via sol-gel process. The phase composition was characterized by means of X-ray diffraction. Polycrystalline samples of Ca3Co2O6 were prepared by a sintering procedure of nanosized power. The seebeck coefficient and electrical conductivity of the samples were measured from 450K up to 750K. The results show that the Seebeck coefficient increases with the increasing temperature. The electronic structures were calculated using the self-consistent full-potential linearized augmented plane-wave (LAPW) method within the density functional theory. The relationship between thermoelectric property and electronic structures was discussed.

MicroRNAs (miRNAs) and promoter methylation are two vital important mechanisms for transcriptional inactivation of a gene in human cancer; VEZT gene is a plasma membrane component of adherens junctions, the role of VEZT still remains largely unexplored in gastric cancer. In the study, we analyzed the expression of VEZT gene in 30 pair matched gastric neoplastic and adjacent non-neoplastic tissues by quantitative real-time PCR, and we show that VEZT mRNA expression was significantly reduced in 30 pairs of gastric cancer specimens compared to matched normal gastric tissues. Methylation specific-PCR (MSP) and bisulfite sequence-PCR (BSP) methods showed hypermethylation status of promoter site of all gastric cancer cell lines. After DNA methylation inhibitor 5-Aza-2-deoxycytidine (5-Aza-CdR) treatment on gastric cancer cell lines, the gene protein level was improved and suppresses cell cycle progression remarkably. Furthermore, a luciferase reporter assay demonstrates that miR-43c directly targets adherens junctions’ transmembrane protein (VEZT) and suppresses VEZT protein expression. These findings help clarify the molecular mechanisms involved in gastric cancer and indicate that VEZT gene may be a bona fide methylation-based treatment of gastric cancer.

Aimed at the disadvantage of current research of shill bidding with different online auctions types, in this paper, applying decision analysis method and game theory, firstly, we research the bidderpsilas optimal biding strategy on english auction and first-price sealed-bid auction with shill biding. secondly, we discuss the relations between the sellerpsilas revenue and probability of shill biding and commission rate under two important auctions types. finally, we use honest bidderpsilas expected gain and honest sellerpsilas revenue as a basis to compare these two important auctions types, and interpret some bidding behavior in practice and give some suggestion.

Algorithms in cryptosystem such as RSA and Diffie-Hellman require the large integer multiplication. This paper introduces classical Knuth multiplication, Karatsuba multiplication and their time complexity, on the basis of which a new Karatsuba trick is presented and proved to be available in theory and in practice. The experiment result reveals that the improved Karatsuba multiplication is more efficient for implementation of large integer multiplication.

In this paper, we first analyze the characteristics of online auction and propose a general analysis framework about the design of online auction. Based on the properties of online auction and a general analysis framework related to the design of online auction, then we discuss the multi-unit dynamic programming models of sequential online auction in order to maximize the seller' expected profits whether the reserve price is private or public. It is shown that the seller with private reserve price can gain the bigger profits than the seller with public reserve price. Finally, numerical results for two cases are given, where we compute the maximal expected total revenue. We show that the numerical results are consistent with the theoretical analysis.

In this paper, we first analyze the characteristics of online auction and propose a general analysis framework about the design of online auction. We believe that the auctions rules, the random arrival process of bidders, the auctions time, the lot size and the auctions costs need to be considered on Internet auctions. Based on the properties of online auction and a general analysis framework related to the design of online auction, then we present single-unit and multi-unit optimal auction models in order to maximize the seller' expected profits whether the reserve price is public or private respectively. In single-unit auction, when the seller with public or private reserve price gain the maximal expected profit respectively, the optimal public reserve price is higher than the optimal private reserve price. In multi-unit auction, it is shown that the seller with private reserve price can gain the bigger profits than the seller with public reserve price. Finally, numerical results for two cases are given, where we compute the maximal expected total revenue. We show that the numerical results are consistent with the theoretical analysis.

The incidence of low and middle rectal cancer is high in China. Researches on improving treatment efficacy of this disease have constantly been concerned. This study was to evaluate the correlation of clinicopathologic features to the prognosis in low and middle rectal cancer.The clinicopathologic data of 599 patients with low and middle rectal cancer, treated from 1990 to 1999 in Cancer Center of Sun Yat-sen University, were analyzed retrospectively. Curative resection was performed for all patients, including abdominoperineal resection (ARP, 355 cases) and low anterior resection (LAR, 244 cases). Survival rate was calculated using life table method, and differences between survival curves were tested by log-rank test. Cox regression model was used for multivariate prognostic analysis.The overall 5-year survival rate was 70.7%; it was significantly lower in APR group than in LAR group (67.5% vs. 75.2%, P=0.026). Univariate analysis showed that local recurrence, perioperative blood transfusion, lymph node metastasis, T stage, histology, macropathology, operation pattern, and distance from anal margin were correlated to prognosis (P0.05). Multivariate analysis showed that local recurrence, perioperative blood transfusion, lymph node metastasis, and T stage were independent prognostic factors (P0.01).Local recurrence, perioperative blood transfusion, lymph node metastasis, and T stage are important prognostic factors of low and middle rectal cancer. LAR has become the preferred option in curative surgery for low and middle rectal cancer.

The damage in fused silica and CaF2 crystals induced by wavelength tunable femtosecond lasers is studied. The threshold fluence is observed to increase rapidly with laser wavelength lambda in the region of 250-800 nm, while it is nearly a constant for 800

To evaluate the biological and clinical characteristics of miR-622 in gastric cancer.We analyzed the expression of miR-622 in 57 pair matched gastric neoplastic and adjacent non-neoplastic tissues by quantitative real-time polymerase chain reaction. Functional analysis of miR-622 expression was assessed in vitro in gastric cancer cell lines with miR-622 precursor and inhibitor. The roles of miR-622 in tumorigenesis and tumor metastasis were analyzed using a stable miR-622 expression plasmid in nude mice. A luciferase reporter assay was used to assess the effect of miR-622 on inhibitor of growth family, member 1 (ING1) expression.Expression of miR-622 was down-regulated in gastric cancer. MiR-622 was found involved in differentiation and lymphatic metastasis in human gastric cancer. Ectopic expression of miR-622 promoted invasion, tumorigenesis and metastasis of gastric cancer cells both in vitro and in vivo. ING1 is a direct target of miR-622.These findings help clarify the molecular mechanisms involved in gastric cancer metastasis and indicate that miR-622 modulation may be a bona fide treatment of gastric cancer.

Self-assembling of colloidal particles dispersed in a mixture of ethanol and water at the air-liquid interface of the colloidal suspension at room temperature is investigated, and a method of rapidly assembling colloidal particles is proposed. By this method, a uniform colloidal crystal thin film over ten square centimeters in area can be fabricated in 10 min without special facilities and heating the suspension. SEM images and a normal incidence transmission spectrum of the sample show that the colloidal crystal film fabricated by this method is of high quality. In addition, this method is very suitable for fabricating colloidal crystal heterostructures.

Colloidal photonic crystal heterostructures, composed of two opaline photonic crystal films of silica spheres with different diameters, are fabricated by a two-step spin-coating method. Scanning electron microscopy (SEM) and UV-vis spectrophotometer are used to characterize the heterostructures. The SEM images show good ordering of the two-layer colloidal crystals constituting the heterostructures. The transmission spectra measured from the (111) plane in the heterostructure show that the composite colloidal photonic crystals have double photonic stop bands. Furthermore, when the sizes of the silica spheres used for fabricating the composite photonic crystal are slightly different, the transmission spectrum shows that the composite photonic crystals have more extended bandgap than that of the individual photonic crystals due to partial overlapping of its two photonic stop bands.

Ordered colloidal particle films with double layers and dual members could be prepared by stepbystep spincoating method. Monolayer film of larger sized PS or SiO2 colloids was utilized as template to selfassemble second layer of SiO2 colloidal particles with smaller diameter. The size ratio γ of smaller and larger colloidal particles was 0.20—0.56 in the composite films. Larger （L） and smaller （S） dual member colloidal particles formed composite crystalline doublelayer films with multifarious arraymodes, whose structures could be expressed as LSx （here, L represents larger sized particles, S represents smaller colloidal particles, and x represents the stoichiometry of larger and smaller colloidal particles）, and x=1, 2, …, 13. The performance of composite colloidal films were influenced mainly by several factors, including spincoating velocity, spincoating time, viscosity of suspension medium, number density of colloidal suspension, and the wetting properties of substrates, etc.. On the prerequisite of complete wetting between colloidal suspension and substrate, appropriate number density of colloidal suspension, velocity and time of spincoating were the necessary conditions for ordered selfassembling to crystalline film of colloidal particles by spincoating method.

The mechanism of polystyrene submicrospheres assembling in aqueous suspension was studied systemically. During the evaporation of solvent, the PS spheres were transported to the water-air inter-surface, where these spheres self-assemble into colloidal crystal through the capillary force between the particles at water-air interface. The wettability of the PS spheres at the water-air interface changes from complete wetting to partial wetting and finally to non-wetting with the evaporation of water, so that the contact angle between the PS spheres and water increases gradually. The experiment showed that only after the contact angle reached a critical value θ′critical, could the PS sphere-assembly occur. The critical value θ′critical obtained from the Wenzel equation was greater than the measured value θcritical＝22° because the surface of the PS colloidal crystal was “regularly” coarse. The change of the PS spheres at water-air interface from the hydrophilic to hydrophobic is essential for the PS spheres to assemble into colloidal crystals.

Three-dimensionally ordered macroporous polystyrene was successfully synthesized through using silica sphere colloid crystals as template and in-situ polymeriza tion of styrene inside the template. The silica spheres with a diameter of 330 n m and 2.75% relative standard deviation were prepared by seeding method. For th e purpose of improving the wetting ability between the silica particles and styr ene, the hydrophilic surface of silica particles was switched to hydrophobic by 3-Aminopropyl-triethoxysilan (APS). Three-dimensionally ordered colloidal crystal was prepared by assembling the modified particles through a vertical depositio n technique at 30℃ for 48h. Styrene monomer was filled into the void of the tem plate and the polymerization of the styrene was carried out at 60℃ for 6h, being used (put the initiator in here) as initiator. The three-dimensionally ordered macroporous polystyrene was thus obtained by removing the silica template from polystyrene materials with 04% HF. The macroporous polystyrene shows a beautif ul iridescence in reflected light, which resulted from Bragg diffraction. SEM im ages indicated that the pores with a diameter of about 210nm were arrayed period ically and connected with each other.

Sulfur is a nonmetallic element necessary for life. Sulfur nanopartieles display unique physical and chemical feature because of effects such as the quantum size effect, mini size effect, surface effect and macro-quantum tunnel effect. So sulfur nanoparticles would present higher efficacies such as removal of heavy metals, radical-scavenging, antimicrobial activity, antioxidant and antitumor activities. It is used as a fungicide product in agriculture, also used in medicine, to obtain sulfur fertilizers and cosmetics industries, as well as in obtaining nanocomposite lithium batteries. In synthesis of sulfur nanowires with carbon to from hybrid materials with useful properties for gas sensor and catalytic applications. This work presents the results of obtaining the sulfur nanoparticles, which can be used in agriculture as a fungicide treatment. Sulfur nanoparticles were obtained by modifying the surface of sulfur by various surfactants including cetyltriammoniumbromide (CTABr), Sulfanol, Sodium Ligninsulfonate (CMN), Sodium salt of polynaphthalene sulphonic acid (NNO), water soluble polymer sodium carboxymethylcellulose (NaCMC), mineral mixtures and their compositions. The size and the structure of sulfur nanoparticles were determined by methods as LSA, XRD, SEM. Been studied the value of adsorption at the interface of solid/gas. It is shown that the nanoparticles have a sulfur monoclinic B-form, and their average size is in the range 500-1000 nm. The received products can be considered as perspective forms of application in agriculture.