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5 results on '"Chianura, L"'

1. The Role of F-18 FDG PET in the Diagnosis of Visceral Leishmaniasis: Two Case Reports

Author

Chianura L, Puoti M, Rossetti C, Colussi G, Popescu Ce, Cantoni S, and De Ferrari Me

Subjects
Fluorodeoxyglucose, Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Spleen, Mononuclear phagocyte system, Disease, medicine.disease, Visceral leishmaniasis, medicine.anatomical_structure, Biopsy, Medicine, Bone marrow, Fever of unknown origin, business, medicine.drug
Abstract

Visceral leishmaniasis (VL) is endemic in Mediterranean countries. Among immunosuppressed patients, the disease can manifest with atypical clinical features. An unusual clinical manifestation of the disease is fever of unknown origin (FUO). F-18 fluorodeoxyglucose positron emission tomography-computed tomography (F-18 FDG PET) may be useful for detecting inflammatory foci by observing increased metabolism in activated granulocytes and macrophages. We report two cases of PET/CT total body imaging showing a diffuse increase of reticuloendothelial metabolic activity in the spleen and vertebral bodies in two patients diagnosed with VL by direct detection of amastigotes in bone marrow biopsy.

Published
2014

3. Clinical management of imported malaria in Italy: Results from a national cross-sectional survey in 2015

Author

Lepore, L., Vairo, F., D Abramo, A., Grilli, E., Corpolongo, A., Scorzolini, L., Nisii, C., Calleri, G., Castelli, F., Chirianni, A., Ippolito, G., Nicastri, E., Andreoni, M., Angarano, G., Anselmo, M., Ascoli Bartoli, T., Bartoloni, A., Bassi, P., Bevilacqua, N., Bisoffi, Z., Cacopardo, B., Caligaris, S., Calzetti, C., Casolari, S., Cassola, G., Chianura, L., Chiodera, A., Conforto, M., Coppola, N., Luca, A., Feasi, M., Ferrari, C., Filippini, P., Foti, G., Francavilla, E., Fusco, F. M., Tekle, S. G., Giancola, M. L., Giammario, A., Giobbia, M., Giordani, M. T., Gobbi, F., Gori, A., Grossi, P., Iacobello, C., Iannetta, M., Libanore, M., Luzzati, R., Magnani, G., Manfrin, V., Mariano, A., Mastroianni, C., Mazzotta, F., Mecocci, L., Mondardini, V., Montineri, A., Nicolini, L. A., Oliva, A., Palazzolo, C., Pasquale, G., Portelli, V., Puoti, M., Quirino, T., Santantonio, T. A., Sarmati, L., Sciotti, M. P., Scotton, P., Tomasoni, L. R., Toscanini, F., Tunesi, S., Elisa Vanino, Viale, P., Viganò, P., Viscoli, C., Vullo, V., Lepore, L., Vairo, F., D'Abramo, A., Grilli, E., Corpolongo, A., Scorzolini, L., Nisii, C., Calleri, G., Castelli, F., Chirianni, A., Ippolito, G., Nicastri, E., Andreoni, M., Angarano, G., Anselmo, M., Ascoli Bartoli, T., Bartoloni, A., Bassi, P., Bevilacqua, N., Bisoffi, Z., Cacopardo, B., Caligaris, S., Calzetti, C., Casolari, S., Cassola, G., Chianura, L., Chiodera, A., Conforto, M., Coppola, N., De Luca, A., Feasi, M., Ferrari, C., Filippini, P., Foti, G., Francavilla, E., Fusco, F. M., Tekle, S. G., Giancola, M. L., Giammario, A., Giobbia, M., Giordani, M. T., Gobbi, F., Gori, A., Grossi, P., Iacobello, C., Iannetta, M., Libanore, M., Luzzati, R., Magnani, G., Manfrin, V., Mariano, A., Mastroianni, C., Mazzotta, F., Mecocci, L., Mondardini, V., Montineri, A., Nicolini, L. A., Oliva, A., Palazzolo, C., Pasquale, G., Portelli, V., Puoti, M., Quirino, T., Santantonio, T. A., Sarmati, L., Sciotti, M. P., Scotton, P., Tomasoni, L. R., Toscanini, F., Tunesi, S., Vanino, E., Viale, P., Vigano, P., Viscoli, C., and Vullo, V.

Subjects
Plasmodium, Travel, Clinical Management, Imported Malaria, Italian National Survey, Plasmodium falciparum, Malaria, Antimalarials, Cross-Sectional Studies, Humans, Italy, Retrospective Studies, Surveys and Questionnaires
Abstract

In Italy, malaria continues to be one of the most common imported parasitoses; therefore, continuous surveillance of epidemiological data and clinical management is needed. In 2016, the National Institute for Infectious Diseases 'Lazzaro Spallanzani' in Rome promoted a retrospective questionnaire-based survey to assess the clinical management of imported malaria cases in Italy in 2015. The questionnaire was sent to 104 Tropical and/or Infectious Diseases Units in the country, and 37 of them filled out and returned the questionnaires. A total of 399 malaria cases were reported in 2015, mostly caused by Plasmodium falciparum and imported from Africa. Malaria chemoprophylaxis was correctly used by a minority of patients. Most patients presented with uncomplicated malaria and were treated orally. In severe cases, intravenous artesunate or quinine alone or in combination were administered, although one third of these severe cases received oral treatment. This retrospective survey reveals a lack of homogeneity in management of malaria-imported cases in Italy. Improvement of malaria chemoprophylaxis, standardization of clinical management of malaria cases and harmonization of oral and intravenous drug availability are needed throughout the country.

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