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Closure spaces are a generalisation of topological spaces obtained by removing the idempotence requirement on the closure operator. We adapt the standard notion of bisimilarity for topological models, namely Topo-bisimilarity, to closure models -- we call the resulting equivalence CM-bisimilarity -- and refine it for quasi-discrete closure models. We also define two additional notions of bisimilarity that are based on paths on space, namely Path-bisimilarity and Compatible Path-bisimilarity, CoPa-bisimilarity for short. The former expresses (unconditional) reachability, the latter refines it in a way that is reminishent of Stuttering Equivalence on transition systems. For each bisimilarity we provide a logical characterisation, using variants of the Spatial Logic for Closure Spaces (SLCS). We also address the issue of (space) minimisation via the three equivalences.

Spatial and spatio-temporal model checking techniques have a wide range of application domains, among which large scale distributed systems and signal and image analysis. In the latter domain, automatic and semi-automatic contouring in Medical Imaging has shown to be a very promising and versatile application that can greatly facilitate the work of professionals in this domain, while supporting explainability, easy replicability and exchange of medical image analysis methods. In recent work we have applied this model-checking technique to the (3D) contouring of tumours and related oedema in magnetic resonance images of the brain. In the current work we address the contouring of (2D) images of nevi. One of the challenges of treating nevi images is their considerable inhomogeneity in shape, colour, texture and size. To deal with this challenge we use a texture similarity operator, in combination with spatial logic operators. We apply our technique on images of a large public database and compare the results with associated ground truth segmentation provided by domain experts.

The tool voxlogica merges the state-of-the-art library of computational imaging algorithms ITK with the combination of declarative specification and optimised execution provided by spatial logic model checking. The analysis of an existing benchmark for segmentation of brain tumours via a simple logical specification reached state-of-the-art accuracy. We present a new, GPU-based version of voxlogica and discuss its implementation, scalability, and applications.

Recent research on spatial and spatio-temporal model checking provides novel image analysis methodologies, rooted in logical methods for topological spaces. Medical Imaging (MI) is a field where such methods show potential for ground-breaking innovation. Our starting point is SLCS, the Spatial Logic for Closure Spaces -- Closure Spaces being a generalisation of topological spaces, covering also discrete space structures -- and topochecker, a model-checker for SLCS (and extensions thereof). We introduce the logical language ImgQL ("Image Query Language"). ImgQL extends SLCS with logical operators describing distance and region similarity. The spatio-temporal model checker topochecker is correspondingly enhanced with state-of-the-art algorithms, borrowed from computational image processing, for efficient implementation of distancebased operators, namely distance transforms. Similarity between regions is defined by means of a statistical similarity operator, based on notions from statistical texture analysis. We illustrate our approach by means of two examples of analysis of Magnetic Resonance images: segmentation of glioblastoma and its oedema, and segmentation of rectal carcinoma.

In spatially located, large scale systems, time and space dynamics interact and drives the behaviour. Examples of such systems can be found in many smart city applications and Cyber-Physical Systems. In this paper we present the Signal Spatio-Temporal Logic (SSTL), a modal logic that can be used to specify spatio-temporal properties of linear time and discrete space models. The logic is equipped with a Boolean and a quantitative semantics for which efficient monitoring algorithms have been developed. As such, it is suitable for real-time verification of both white box and black box complex systems. These algorithms can also be combined with stochastic model checking routines. SSTL combines the until temporal modality with two spatial modalities, one expressing that something is true somewhere nearby and the other capturing the notion of being surrounded by a region that satisfies a given spatio-temporal property. The monitoring algorithms are implemented in an open source Java tool. We illustrate the use of SSTL analysing the formation of patterns in a Turing Reaction-Diffusion system and spatio-temporal aspects of a large bike-sharing system., Comment: 36 pages with 13 figures

We address the specification and verification of spatio-temporal behaviours of complex systems, extending Signal Spatio-Temporal Logic (SSTL) with a spatial operator capable of specifying topological properties in a discrete space. The latter is modelled as a weighted graph, and provided with a boolean and a quantitative semantics. Furthermore, we define efficient monitoring algorithms for both the boolean and the quantitative semantics. These are implemented in a Java tool available online. We illustrate the expressiveness of SSTL and the effectiveness of the monitoring procedures on the formation of patterns in a Turing reaction-diffusion system.