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Objectives: The aim of this study was to investigate the 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and calcitonin levels and lipid profiles in patients with calcaneal spurs. Patients and methods: Between March 2018 and June 2019, a total of 50 patients (30 males, 20 females; mean age: 39.8±8.1 years; range, 24 to 54 years) admitted to our clinic with heel pain and diagnosed with heel spurs based on radiographic images were included. The control group consisted of 50 age- and sex-matched healthy volunteers (32 males, 18 females; mean age: 35.7±9.6 years; range, 20 to 56 years). Blood samples were collected from all participants. Total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride, phosphate, and calcium levels were measured using the colorimetric method. The PTH and 25(OH)D levels were measured using the chemiluminescent microparticle immunoassay. Calcitonin levels were detected using the chemiluminescent immunometric assay. Results: In the patients with calcaneal spurs, 25(OH)D and HDL-C levels were significantly lower (p Conclusion: Our study results suggest that calcaneal spur formation is associated not only with weight-related pressure, but also with lipid levels and hormonal alterations involved in calcium metabolism. Based on these findings, hormonal alterations and lipids should be considered in patients with calcaneal spurs.

© 2021, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.Reduced mobility due to COVID-19 prevention measures caused major changes in the number and types of orthopedic trauma cases. This study aimed to compare the profile of trauma-related general orthopedic surgery and hand surgery cases between the first six months of the COVID-19 pandemic and the corresponding periods of previous years in order to determine strategies for managing orthopedic traumas in unusual circumstances such as pandemics. Patients over 18 years old who underwent orthopedic surgery due to trauma were grouped according to sur gery date as pre-pandemic group 1 (G1, March 16–September 18, 2018), pre-pandemic group 2 (G2, March 18–September 20, 2019), and the pandemic group (G3, March 19–September 21, 2020). Between-group differences with p

Aim: Mosaicplasty is a common surgical technique performed in patients with osteochondritis dissecans (OCD) of the knee. In the present study, we aimed to investigate the effectivity of mosaicplasty followed by intraarticular hyaluronic acid (HA) injection on the functional outcomes of the knee joint in patients with osteochondral lesions of the knee. Methods: The retrospective study included 41 patients (32 men and 9 women) that underwent mosaicplasty due to the detection of an OCD lesion larger than 1 cm2 on magnetic resonance imaging (MRI). The patients were randomly divided into HA (n=22) and control (n=19) groups. The HA group received 2 ml of HA injection at two weeks after surgery and the control group received no additional treatment. At postoperative months 6 and 12, functional outcomes of the patients were graded using the Lysholm knee score and pain intensity was assessed using Visual Analog Scale (VAS) in both groups. Results: The HA group included 22 (53.7%) and the control group included 19(46.3%) patients. The mean age was 31.5 in the HA group and 31.47 years in the control group. The Lysholm scores at postoperative months 6 and 12 were significantly higher in the HA group compared to the control group (p

The patient presented in this study had a form of chronic sclerosing osteomyelitis (CSO) that is rarely reported in calvarial bones and has never been reported in the frontal bone in the literature. We aimed to contribute to the literature with this case study. In this study, we report a 14-year-old girl who presented with swelling and pain in the frontal bone and underwent treatment due to CSO. The patient had no history of trauma and chronic infection. We conclude that CSO should be considered in the differential diagnosis of the patients presenting with cranial swelling whose diagnosis cannot be established based on the radiological findings.

Background Osteomyelitis (OM) is a local or generalised infection of the bone and bone marrow which may be multifactorial in its causation. In this study, we aimed to determine oxidative DNA damage and antioxidant status of patients with chronic osteomyelitis. Material method In this study, patients with chronic osteomyelitis and healthy controls were compared for descriptive characteristics (age and gender) and serum levels of malondialdehyde (MDA), 8-hydroxy-2-deoxy guanosine and antioxidant enzymes catalase, glutathione and superoxide dismutase. Results This was a case-control study. About 5 mL of venous blood was collected for the estimation of biochemical parameters. This study comprised of 36 OM patients diagnosed, and 41 healthy ages (25-55 years) and sex-matched individuals. Antioxidant enzyme levels were significantly lower in patients with OM, whereas MDA and oxidative DNA damage levels were significantly higher. Conclusion The results obtained from this study have shown that the oxidant-antioxidant balance is impaired in patients with chronic osteomyelitis. It also supports that chronic osteomyelitis has associated with oxidative DNA damage.

BACKGROUND: Osteomyelitis, followed by trauma or inflammation relates to a surgical procedure and is the concept caused by pyogenic bacteria in the bone marrow and bone. Treatment is difficult because management usually relies on a multidisciplinary approach. Up to date, there is no study in the literature investigating the effect of trauma and the causative microorganism on the duration of treatment in chronic osteomyelitis.

To investigate the medium-term outcomes of the patients who underwent revision total knee arthroplasty, and to come to a conclusion regarding the efficacy of the method by comparing these with literature data. 34 knees of 33 patients who underwent revision knee arthroplasty operation between January 2008 and January 2012 and were sufficiently followed-up were included into this study. Single-stage revision knee arthroplasty was performed for 25 knees for aseptic reasons, and two-stage revision knee arthroplasty was performed for 9 knees for septic reasons. For all patients, alpha, beta, gamma, sigma and total valgus angles were measured in pre-and post-operative anteroposterior (AP) X-rays and lateral X-rays based on American Knee Society radiological assessment form. For all patients, pre-and post-operative American Knee Society knee score and functional score was assessed. As laboratory work-up, all patients’ pre-and post-operative erythrocyte sedimentation rate, C-reactive protein, white blood cells values were compared. The patients’ mean knee score and functional score was detected to be 34.7 (4-57) and 33.5 (5-55), respectively, and to be 78.2 (62-90) and 73.8 (50-90) after revision. In pre-operative assessments performed based on Knee Society radiographic assessment form, mean alpha angle was found to be 95.3 (77-103), mean beta angle to be 84.8 (71-100), mean gamma angle to be 5.8 (0-30), mean sigma angle to be 83.3 (49-97), and mean total valgus angle to be 0.1 (-13-12). In post-operative assessments, mean alpha angle was found to be 94.7 (90-99), mean beta angle to be 88.4 (84-92), mean gamma angle to be 3.7 (0-10), mean sigma angle to be 88.1 (85-92), and mean total valgus angle to be 3.1 (-1-8). We think that when revision knee arthroplasty operation is performed for proper indication and according to the surgical technique, it is a highly effective and preferable method in decreasing the pain severity and improving the life quality of the patients. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.

Aim: Lower limb amputations (LLA) are considered as a serious psychosocial condition. The causes of amputation in young persons are generally trauma, work accidents, or tumors, while in geriatric patients, it is mostly vascular problems. The aim of this study is to determine the causes and levels of LLA of geriatric patients in a tertiary care center.Materials and Methods: In order to conduct this study, information was obtained from the automation records of geriatric patients who underwent LLA in our clinic between the years 2014 and 2017. We divided our patients into three groups according to their ages. Group 1 consisted of those patients in the age group of 65-74 years, Group 2: 75-84 years, and Group 3: 84-95 years. We also classified our patients according to amputation causes and levels.We classified the patients as above-knee, transtibial, metatarsal, and toe amputation according to the level of lower extremity amputation.Results: Of the 96 patients included in the study, 70 were male (72.9%), and 26 (27.1%) were female. Group 1 consisted of 45 patients, group 2had 38 patients, and group 3 had 13 patients. It was observed that the most common cause of LLA was diabetic foot ulcers (65 patients), followed by ischemic foot as a cause of LLA in 25 patients. Moreover,4 patients were amputated due to a tumor, while amputation was performed in 2 patients as a result of a crush injury. It was observed that metatarsal and toe amputation was the most common amputation type according to amputation levels. (26 patients)Conclusion: As a result of our study, the most common cause of LLA in Geriatric patients was diabetic foot ulcers. Considering that lower extremity amputations cause severe morbidity and mortality in geriatric patients, it is crucial to identify these patients with preventive medicine practices.

PEV is one of the most common deformities in the foot. The incidence of PEV varies between communities and many theories about its etiology have been proposed. In this study, we aimed to share our experience with the incidence and etiology of PEV in the neonatal intensive care unit of a tertiary hospital. 3658 patients who were followed up in a tertiary neonatal intensive care unit from 2014 to 2017 were included in the study. Data on the number and etiology of newborns with PEV deformity were obtained from the automation records of our hospital. PEV deformity was diagnosed in 32 (0.87%) of 3658 babies treated in the neonatal intensive care unit over a period of 3 years. Of these 32 patients, 18 (56.25%) were bilateral, and 14 (43.75%) unilateral PEV. Two (6.25%) of our patients had a positive family history. While 23(71.87%)) of our patients were delivered by cesarean, 9 (28,1%) of our patients were born normally. Considering birth weights, the number of babies born under 2500 grams was 7 (21.8%), and the number of babies born above 2500 grams was 25 (78.1%). Considering the data we obtained at the end of the study, the incidence of PEV was lower than in the literature. In fact, our hypothesis before starting the study was that the incidence of PEV was higher in the neonatal intensive care unit. Although the frequency of PEV is known to vary between populations, the etiology of PEV is not fully known. We believe that future studies (such as genetic studies) will be more beneficial to science than classical knowledge about PEV etiology. [Med-Science 2020; 9(3.000): 556-9]

Kalca eklem cikiklari tum eklem cikiklarinin yaklasik %5’ini olusturmaktadir. En sik posterior kalca eklem cikigi gorulmektedir. Anterior kalca eklemi cikiklari nadir gorulur. Bu yazida, is kazasi sonrasi gelisen ve ameliyathanede sedasyon altinda kapali redukte edilen anterior obturator kalca eklem cikigi olgusu sunulmaktadir. Hastanin 1 yillik takibi sonunda radyografik olarak femur basi avaskuler nekrozu tespit edilmedi. Fizik muayenesinde kalca eklem hareketleri olagan bulundu. Anahtar Kelimeler: Kalca cikigi, kapali reduksiyon, avaskuler nekroz

Amac: Klinigimizde gestasyonel trofoblastik hastalik nedeniyle tedavi edilen hastalarin risk faktorleri, tanisi, yonetimini arastirmayi amacladik. Gerec ve Yontem: Kliniginize Ocak 2010- Agustos 2013 yillari arasinda molar gebelik tanisi almis hastalar taranarak hastalarin yasi, gravide, parite ve abortus bilgileri kaydedildi. Hastalarin sikayeti, muayene, ultrason bulgulari, β HCG ve tam kan sayimi degerleri, hastaligin tedavisi, patoloji sonuclari, hastalarda gelisen komplikasyonlar, takipte β HCG degerleri kayit edildi. Bulgular: Klinigimizde molar gebelik hizi 1000 dogumda 8 olarak bulundu. Hastalarin ortalama yasi 28±4,5 olup ortalama gestasyonel yas 8±3,2 haftaydi. Hastalarin en sik gelis sikâyeti vajinal kanama (n=23, %57,5), amenore (n=10,%25) , karin agrisi (n=6, %15) idi. β HCG degerleri 191 ile 125200 arasinda degismekteydi. Hastalarin 26 (65%) sinda ultrason bulgusu molar gebelik lehine yorumlanmisti. Patoloji sonuclari 26 (%65) hastada parsiyel mol, 13 (%32.5) hastada komplet mol ve 1 (%2.5) hastada koryokarsinom gelmistir. Hastalik ve komplikasyonlarina ait olum olgusuna rastlanmamistir. Sonuc: Klinigimizde molar gebelik hizi 1000 dogumda 8 olup en sik gelis sikâyeti vajinal kanamadir