1. Lattice Dystrophy of the Cornea
- Author
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de Felice Gp and Carta S
- Subjects
Pathology ,medicine.medical_specialty ,genetic structures ,Eye disease ,Dystrophy ,General Medicine ,Biology ,medicine.disease ,eye diseases ,Sensory Systems ,law.invention ,Ophthalmology ,medicine.anatomical_structure ,Stroma ,law ,Cornea ,medicine ,Immunohistochemistry ,Lattice corneal dystrophy ,sense organs ,Electron microscope ,Corneal epithelium - Abstract
Four members of a family were affected with lattice dystrophy of the cornea. One of them showed recurrence of the disease in the corneal graft in one eye 9 years after a keratoplasty, and a very advanced stage of the disease in the fellow eye. Therefore a keratoplasty was done in this eye. The corneal button was thoroughly investigated by means of histochemistry, electron microscopy and X-ray electron microanalysis. Two young members of the family showing early signs of the disease were followed up for 2 years. It has been possible to observe the evolution of their lesions. Histopathological examinations revealed the presence of two different types of abnormal deposits under the epithelium and in the stroma. X-ray electron microanalysis of the stromal deposits revealed a substantial increase in sulphur content.
- Published
- 1986
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