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Objectives: Most studies of knee osteoarthritis use isokinetic peak strength as a measure of muscle strength. However, estimated one-repetition maximum (1-RM) may have a stronger relationship than isokinetic peak strength with daily activities. The aim of this study was to test the following hypotheses: first, the estimated 1-RM is more strongly associated than isokinetic peak strength with daily activities; and secondly, the estimated 1-RM is most strongly associated with the 6-minute walk test (6MWT), followed by the Get Up and Go test (GUG test) and the stair-climb test.Methods: Data were used for 177 patients with knee osteoarthritis from a randomized controlled trial on improving muscle strength. The patients had a mean age of 67.6 ± 5.8 years. Isokinetic peak strength was measured using a dynamometer, 1-RM was estimated with the 10-RM test, and physical performance was measured with the 6-minute walk test (6MWT), get-up and go test (GUG) test and stair-climb test, at the start and end of 12 weeks of resistance training. Linear regression analyses provided standardized betas (β) that were comparable between the different associations between measures of muscle strength and daily activities. Results: Compared with the estimated 1-RM, isokinetic peak strength was more strongly associated with all performance-based measures. The associations between the estimated 1-RM and performance-based tests were not ranked in the order hypothesized (6MWT, GUG test, stair-climb test).Conclusion: Contrary to the first hypothesis, isokinetic peak strength showed stronger associations with all daily activities than did estimated 1-RM. In addition, the second hypothesis regarding the activity-specific pattern for the 1-RM with regards walking, chair rising and stair climbing measurements was not confirmed. LAY ABSTRACTIn patients with knee osteoarthritis, greater muscle strength in the upper leg is linked with better performance in daily activities. To test muscle strength, peak muscle strength is usually measured. This study hypothesized that another test (the one-repetition maximum test) would be a more relevant measure. However, this was not confirmed, and therefore peak muscle strength remains the best measure of muscle strength at present.

Supplemental material, sj-docx-2-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-3-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-5-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-6-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-pdf-1-cre-10.1177_02692155211046463 for Setting meaningful goals in rehabilitation: A qualitative study on the experiences of clients and clinicians in working with a practical tool by Elsbeth Littooij, Suzan Doodeman, Jasmijn Holla, Maaike Ouwerkerk, Lenneke Post, Ton Satink, Anne Marie ter Steeg, Judith Vloothuis, Joost Dekker and Vincent de Groot in Clinical Rehabilitation

Supplemental material, sj-docx-6-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-5-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-4-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-1-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-3-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-2-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Supplemental material, sj-docx-4-cre-10.1177_02692155211073039 for High-intensity versus low-intensity resistance training in patients with knee osteoarthritis: A randomized controlled trial by Arjan H de Zwart, Joost Dekker, Leo D Roorda, Martin van der Esch, Paul Lips, Natasja M van Schoor, Annemiek C Heijboer, Franktien Turkstra, Martijn Gerritsen, Arja H��kkinen, Kim Bennell, Martjin PM Steultjens, Willem F Lems and Marike van der Leeden in Clinical Rehabilitation

Item does not contain fulltext Cancer is associated with sometimes strong emotions. However, emotions are mostly adaptive - they help people adapt to cancer. Adaptive emotions do not need to be treated; instead, emotional support is key. Professional mental health care is indicated only when emotions are no longer adaptive. Oncologists, nurses, and especially general practitioners play an important role in identifying people who qualify for referral to mental health care. Prior mental health problems, a weak social support system, and a relatively stressful disease course or treatment are risk factors for cancer-related emotional problems. Training and the development of professional networks can contribute to optimizing the availability, accessibility and quality of supportive care for mental well-being during and after cancer treatment. In addition, providing good information to patients is important, to enable them to find supportive care.

Additional file 1.

Supplemental material, Appendix_1_Cost_categories_with_unit_prices_ for Economic evaluation of a combined screening and stepped-care treatment program targeting psychological distress in patients with metastatic colorectal cancer: A cluster randomized controlled trial by Mohamed El Alili, Claudia S.E.W Schuurhuizen, Annemarie M.J. Braamse, Aartjan T.F. Beekman, Mecheline H. van der Linden, Inge R. Konings, Joost Dekker and Judith E. Bosmans in Palliative Medicine

E-Exercise is an effective 12-week blended intervention consisting of around five face-to-face physiotherapy sessions and a web-based application for patients with hip/knee osteoarthritis. In order to facilitate effective implementation of e-Exercise, this study aims to identify physiotherapists' experiences and determinants related to the usage of e-Exercise. Methods: An explanatory sequential mixed methods design embedded in a randomized controlled trial comparing e-Exercise with usual physiotherapy in patients with hip/knee osteoarthritis. Usage of e-Exercise was based on recruitment rates of 123 physiotherapists allocated to e-Exercise and objective web-based application usage data. Experiences and determinants related to e-Exercise usage were investigated with a questionnaire and clarified with semi-structured interviews. Results: Of the 123 physiotherapists allocated to e-Exercise, 54 recruited more than one eligible patient, of whom 10 physiotherapists continued using e-Exercise after the study period. Physiotherapists had mixed experiences with e-Exercise. Determinants related to intervention usage were appropriateness, added value, time, workload, professional autonomy, environmental factors, and financial consequences. Physiotherapists recommended to improve the ability to tailor e-Exercise to the individual needs of the patient patients' individual needs. Discussion: Determinants related to the usage of e-Exercise provided valuable information for the implementation of e-Exercise on broader scale. Most importantly, the flexibility of e-Exercise needs to be improved. Next, there is a need for education on how to integrate an online program within physiotherapy

Search strategy. (PDF 84 kb)

Forest plots of data pooling for the effect of semi-rigid FOs versus soft FOs on pain in the subgroups: (a) custom-made FOs versus ready-made FOs, (b) total-contact FOs versus non-total contact FOs, (c) forefoot region of interest, and (d) treatment effect after ≥ 1 month. (PDF 141 kb)

Qualitative data-syntheses. (PDF 209 kb)

Additional file 1. SPIRIT 2013 Checklist.

Framework for diagnosis with an overview of the role of the involved healthcare professions in the Netherlands. (DOCX 816 kb)

Framework for treatment with an overview of the role of the involved healthcare professions in the Netherlands. (DOCX 774 kb)

Integrating physical therapy sessions and an online application (e-Exercise) might support people with hip osteoarthritis (OA), knee OA, or both (hip/knee OA) in taking an active role in the management of their chronic condition and may reduce the number of physical therapy sessions. The objective of this study was to investigate the short- and long-term effectiveness of e-Exercise compared to usual physical therapy in people with hip/knee OA. The design was a prospective, single-blind, multicenter, superiority, cluster-randomized controlled trial. e-Exercise is a 3-month intervention in which about 5 face-to-face physical therapy sessions were integrated with an online application consisting of graded activity, exercise, and information modules. Usual physical therapy was conducted according to the Dutch physical therapy guidelines on hip and knee OA. Primary outcomes, measured at baseline after 3 and 12 months, were physical functioning and free-living physical activity. Secondary outcome measures were pain, tiredness, quality of life, self-efficacy, and the number of physical therapy sessions.

Summary of findings table (DOCX 71 kb).

Background: Blended physiotherapy, in which physiotherapy sessions and an online application are integrated, might support patients in taking an active role in the management of their chronic condition and may reduce disease related costs. The aim of this study was to evaluate the cost-effectiveness of a blended physiotherapy intervention (e-Exercise) compared to usual physiotherapy in patients with osteoarthritis of hip and/or knee, from the societal as well as the healthcare perspective. Methods: This economic evaluation was conducted alongside a 12-month cluster randomized controlled trial, in which 108 patients received e-Exercise, consisting of physiotherapy sessions and a web-application, and 99 patients received usual physiotherapy. Clinical outcome measures were quality-adjusted life years (QALYs) according to the EuroQol (EQ-5D-3 L), physical functioning (HOOS/KOOS) and physical activity (Actigraph Accelerometer). Costs were measured using self-reported questionnaires. Missing data were multiply imputed and bootstrapping was used to estimate statistical uncertainty.

Overview of the developed research questions and the used answering methods. (DOCX 51 kb)

CONSORT Cluster Randomized Trial checklist. (DOCX 34 kb)

Cost questionnaire (translation of Dutch version). (DOC 70 kb)

CHEERS Checklist. (PDF 571 kb)

Blended behavior change interventions combine therapeutic guidance with online care. This new way of delivering health care is supposed to stimulate patients with chronic somatic disorders in taking an active role in their disease management. However, knowledge about the effectiveness of blended behavior change interventions and how they should be composed is scattered. This comprehensive systematic review aimed to provide an overview of characteristics and effectiveness of blended behavior change interventions for patients with chronic somatic disorders.

Objective. We introduced a stepped-care strategy (SCS) for hip and knee osteoarthritis, focusing on delivery of highquality stepped care. In this study, we aimed to identify factors associated with various steps of the SCS. Methods. We used data from a 2-year observational prospective cohort study, including 313 patients visiting their general practitioner (GP) with a new episode of hip/knee osteoarthritis. We used logistic multilevel analyses to identify factors at the level of the patient, the GP, and the general practice, related to treatment limited to primary care, referral to nonsurgical secondary care, or surgical procedures.

This study explores which patient-, intervention-, and environment-related factors are determinants of adherence to the online component of e-Exercise, a 12-week blended intervention for patients with hip and/or knee osteoarthritis.

Background Blended care, a combination of online and face-to-face care, is seen as a promising treatment option. However, actual use of blended interventions in practice is disappointing. Objective The objective of this study was two folded. The first aim was to develop a blended exercise therapy intervention for patients with knee and hip osteoarthritis that matches the values of the users and that can be implemented in the daily routine of physical therapists. The second aim was to investigate the feasibility through interviews and a pilot study. Methods In this paper, we employed the first 3 steps of the CeHRes road map to develop a blended intervention for patients with knee and hip osteoarthritis. We used interviews, a focus group and discussions with stakeholders to explore the needs, values, and requirements with respect to our to-be-developed blended intervention, which we called e-Exercise. The first version of e-Exercise was tested in a pilot study. Feasibility outcomes, including recruitment rates within each practice, website usage (assignments completed and website visits), and user satisfaction, were measured. In addition, therapists and patients from the pilot study were interviewed to investigate users’ experiences. Results The study captured important information about stakeholders’ needs and perspectives. Based on our findings, we created a first version and attuned the application’s content, functionality, and structure. Patients and, to lesser extent, physical therapists were satisfied with the e-Exercise intervention. Eight patients were recruited by 8 physical therapists. Of the 8 patients, 6 completed more than 7 of 12 modules. Conclusions This study outlines the development and feasibility of a blended exercise therapy intervention for patients with knee and hip osteoarthritis. E-Exercise offers an alternative approach in the physical therapy treatment of knee and hip osteoarthritis. This study provides valuable information to conduct a further trial to evaluate the (cost) effectiveness of e-Exercise compared to usual physical therapy.

Patiënten met hematologische kanker die hiervoor een autologe stamceltransplantatie ondergaan, staan voor de moeilijke taak om te gaan met zowel een potentieel levensbedreigende ziekte als een stressvolle behandeling. Een deel van deze patiënten rapporteert psychologische klachten. Behandeling van deze klachten verdient aandacht en zal naar verwachting leiden tot een verbetering van de kwaliteit van leven van deze patiënten. In dit artikel beschrijven we de implementatie van een zorgprogramma gericht op vermindering van psychologische klachten, met als belangrijkste onderdeel het internetzelfhulpprogramma ‘Stress onder controle’

promotiedatum: 20-6-2014 � prom-id: 11414