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Additional file 1: Supplementary Figure 1. The sensitivity analyses of CEC difference in coronary artery disease (CAD) and non-CAD group. CEC, cholesterol efflux capacity. The figure depicts pooled results of random-effect meta-analyses considering the remaining studies after excluding named study. Supplementary Figure 2. The funnel of CEC difference in coronary artery disease (CAD) and non-CAD group. CEC, cholesterol efflux capacity. Supplementary Figure 3. A The sensitivity analyses of CEC and the risk of coronary artery disease (CAD). CEC, cholesterol efflux capacity. The figure indicates the pooled results of the remaining studies after excluding named study (Study of Li MX includes two cohort). B. The sensitivity analyses of CEC and CAD risk by per 1-SD increasement. CEC, cholesterol efflux capacity. SD, standard deviation. Supplementary Figure 4. The funnel of CEC and CAD risk. CEC, cholesterol efflux capacity. CAD, coronary artery disease. Supplementary Figure 5. The sensitivity analyses of CEC and the risk of cardiovascular mortality. CEC, cholesterol efflux capacity. Supplementary Table 1. Subgroup Analyses. Supplementary Table 2. Quality Assessment of the 18 observational Studies. Supplementary Table 3. Characteristics of 18 Observational Studies.