1. The effect of charge location in ion mobility mass spectrometry for small molecule analytes
- Author
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Lapthorn, Cris, McCullagh, Mike, Perkins, George, Dines, Trevor, Pullen, Frank, Babur Chowdhry, and Allen, Mark
- Abstract
Presented at the British Mass Spectrometry Society meeting in 2014 and awarded the Bordoli Prize In travelling wave IM-MS an electric field is applied across the IMS cell and analyte collisions with the inert gas give rise to a relationship between the drift time and the molecular shape and overall charge. Recent findings show near baseline IMS separation (R>1) where shape and overall charge appear not to explain the IMS separation. Multiple ion mobility peaks are observed for a single m/z including the fluoroquinolone antibiotics norfloxacin and lomefloxacin, the pesticide indoxacarb and a number of steroids. The Bordoli Award was judged by Prof. Graham Cooks (Henry Bohn Hass Distinguished Professor of Chemistry at Purdue University, ISI Highly Cited Chemist with over 950 publications and an H-index of 81) and Prof. Mike Morris (Senior Director MS Research at Waters).
- Published
- 2014
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