1. Left Ventricular Filling Pressure as a Useful Marker of Myocardial Injury Following Elective Percutaneous Coronary Intervention
- Author
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M.D. Ayman El-Said Ehab El-Guindy and M.Sc. Ayman Gafaar Amr M.N. El-Sheikh
- Subjects
medicine.medical_specialty ,Percutaneous ,business.industry ,medicine.medical_treatment ,Percutaneous coronary intervention ,Preload ,Internal medicine ,Cohort ,Conventional PCI ,Cardiology ,medicine ,Sinus rhythm ,cardiovascular diseases ,Correlation test ,Ventricular filling ,business - Abstract
Background: Advances in Percutaneous Coronary Inter-vention (PCI) techniques have improved patient outcome. However, occurrence of myonecrosis after elective PCI has been extensively debated.Aim of Study: We investigated the value of the ratio of early transmittal velocity to tissue Doppler mitral annular early diastolic velocity (E/E') in detecting the occurrence of peri-procedural myocardial injury in patients undergoing elective PCI.Patients and Methods: Sixty two patients undergoing elective PCI were recruited prospectively. All participants had EF% >50% and sinus rhythm. E/E' ratio was measured immediately before, and within 24 hours after PCI. CK-MB and cardiac troponin (cTn) were measured in the same day after successful PCI to diagnose myocardial injury.Results: The cohort age was 56.7±9.7 year, and consisted of forty four (71%) males, 49 (27.4%) had ³ two risk factors for CAD, 60% were symptomatic before PCI. Thirty (48.4%) patients had regional wall motion abnormalities (regional Wall Motion Score Index (WMSI): 0.74±0.29). Myocardial injury was diagnosed by elevated cTn in 39 (62.9%) patients. Patients with predilation showed reduction of LVEDP as estimated by D E/E' (8.9±2.9 Vs. 7.9±3.2, p
- Published
- 2019