10 results on '"Fedeli P"'
Search Results
2. Protesi in Chirurgia Plastica
- Author
-
D'ANDREA, Francesco, FERRARO, Giuseppe, Brongo S, Vacchiano G. Fedeli P, Perna L., D'Andrea, Francesco, Ferraro, G, Brongo, S, Vacchiano G., Fedeli P, Perna, L., Palmieri L, Edizioni Minerva Medica, and Ferraro, Giuseppe
- Published
- 2003
3. Management of neoplastic pericardial effusions
- Author
-
Vincenzina Amodei, Sergio Cozzi, Annalisa Luraschi, Sergio Montanara, Elisabetta Garzoli, Paola Buscaglia, Aldo Gioria, Ornella Fossati, Gianmarco Ferrari, and Fedeli P
- Subjects
Adult ,Male ,Cancer Research ,medicine.medical_specialty ,Lung Neoplasms ,Lymphoma, B-Cell ,medicine.medical_treatment ,Breast Neoplasms ,ThioTEPA ,Pericardial effusion ,Pericardial Effusion ,Breast cancer ,Cardiac tamponade ,medicine ,Humans ,Lung cancer ,Aged ,business.industry ,Standard treatment ,Pericardiocentesis ,General Medicine ,Middle Aged ,medicine.disease ,Survival Analysis ,Surgery ,Cardiac Tamponade ,Treatment Outcome ,Oncology ,Adenocarcinoma ,Female ,business ,medicine.drug - Abstract
Aims and background. Malignant pericardial effusion and cardiac tamponade are known complications of many advanced malignancies such as breast cancer, lung cancer,lymphomasandleukemias.Overallsurvivalislow,duetoothermetastaticlo calizations. The present study evaluated the clinical outcome and prognosis in pa tients with advanced cancer with pericardial effusion. Methods. We studied 7 patients, 4 men and 3 women, with malignant pericardial ef fusion, affected by breast cancer (2 patients), lung cancer (adenocarcinoma in 3 pa tients, microcytoma in 1 patient), and B-cell non-Hodgkin lymphoma (1 patient). All patients underwent pericardiocentesis; 3 patients underwent an instillation of thiotepa. Results. One terminal patient treated with pericardiocentesis died after only a few hours.Alltheremainingpatientsexperiencedimmediatesymptomaticimprovement and no operative complications. At the end of the study period, 2 patients were alive at59and33months,respectively,and4diedofdiseaseprogressionat1to32months (mean, 10.5). Conclusions .Pericardiocentesisisanactivenecessaryapproach,and intrapericardial treatment with thiotepa was able to reduce pericardial effusion and to prevent its reaccumulation.The standard treatment of malignant effusion and cardiac tampon ade has not yet been defined. Physicians should consider the status and the progno sis of each case. Free full text available at www.tumorionline.it
- Published
- 2011
4. Effect of moderate and heavy alcohol consumption on intestinal transit time
- Author
-
Papa, A., Tursi, A., Cammarota, G., Certo, M., Cuoco, L., Montalto, M., Rossella Cianci, Papa, V., Fedeli, P., Fedeli, G., and Gasbarrini, G.
- Subjects
Adult ,Male ,Alcoholism ,Adolescent ,Alcohol Drinking ,Breath Tests ,Ethanol ,Settore MED/12 - GASTROENTEROLOGIA ,Humans ,Female ,Middle Aged ,Gastrointestinal Transit ,Aged - Abstract
Alcohol abusers frequently have gastrointestinal symptoms, such as diarrhea, nausea and vomiting. In the genesis of these symptoms multiple mechanisms are involved, including alteration of gastrointestinal motility. The aim of our study was to investigate oro-cecal transit time (OCTT) using the H2-breath test (H2-BT) in moderate and heavy drinkers.We studied 40 chronic drinkers: 20 with heavy alcohol consumption (or = 60 g/day for men andor = 40 g/day for women) and 20 with moderate alcohol intake (60 g/day for men and40 g/day for women). The control group consisted of 20 teetotal subjects. All subjects underwent a lactulose H2-BT to assess OCTT.OCTT in heavy alcohol drinkers ranged from 100 to 240 min, with a mean of 149.5 min, while OCTT in moderate drinkers ranged from 70 to 140 min, with a mean of 109 min. In the control group the mean OCTT was 100 mins, ranging from 70 to 130 min. The difference between alcohol abusers and controls was statistically significant; on the contrary, there was no statistically significant difference between moderate alcohol drinkers and teetotallers.Our study shows that only in chronic heavy alcohol drinkers is OCTT clearly increased. Multiple mechanisms are hypothesized to explain motility disorder, such as visceral autonomic neuropathy, inflammation and loss of contractile proteins of smooth muscle layer of the small intestine.
- Published
- 1998
5. Regression of a primary gastric MALT lymphoma with extensive antrum lesions by Helicobacter pylori eradication
- Author
-
Cammarota, G., Tursi, A., Cannizzaro, O., Alfredo PAPA, Cuoco, L., Cianci, R., Fedeli, P., Fedeli, G., and Gasbarrini, G.
6. Regression of EI2-stage low-grade gastric MALT-lymphoma after H. Pylori eradication
- Author
-
Cammarota, G., Fedeli, P., Bianchi, A., Rossella Cianci, Martino, A., Fedeli, G., and Gasbarrini, G.
7. Helicobacter pylori infection and ischaemic heart disease
- Author
-
Cammarota, G., Pasceri, V., Papa, A., Rossella Cianci, Gasbarrini, A., Fedeli, P., Cremonini, F., Fedeli, G., Maseri, A., and Gasbarrini, G.
8. Safety and effectiveness of a somatropin biosimilar in children requiring growth hormone treatment: second analysis of the PATRO Children study Italian cohort
- Author
-
G. Bona, Nella Augusta Greggio, Lorenzo Iughetti, H. Zouater, L. Ragusa, Laura Guazzarotti, P. Fedeli, Gabriella Pozzobon, Claudia Giavoli, P. Gallinari, Franco Antoniazzi, C. Zecchino, Gianluca Tornese, Luca Persani, Stefano Zucchini, Stefano Stagi, Roberta Minelli, Tommaso Aversa, Laura Perrone, Iughetti, L., Antoniazzi, F., Giavoli, C., Bona, G., Aversa, T., Greggio, N. A., Guazzarotti, L., Minelli, R., Perrone, L., Persani, L., Pozzobon, G., Ragusa, L., Stagi, S., Tornese, G., Zecchino, C., Gallinari, P., Zouater, H., Fedeli, P., and Zucchini, S.
- Subjects
Male ,Omnitrope ,Pediatrics ,medicine.medical_specialty ,Abdominal pain ,Adolescent ,Endocrinology, Diabetes and Metabolism ,Recombinant human growth hormone ,030209 endocrinology & metabolism ,® ,Adolescents ,Impaired glucose tolerance ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Product Surveillance, Postmarketing ,medicine ,Clinical endpoint ,Humans ,Children ,Infants ,Pediatric ,Longitudinal Studies ,Child ,Adverse effect ,Biosimilar Pharmaceuticals ,Growth Disorders ,Human Growth Hormone ,business.industry ,Infant ,Prognosis ,medicine.disease ,Growth hormone treatment ,Clinical trial ,030220 oncology & carcinogenesis ,Cohort ,Female ,Observational study ,medicine.symptom ,business ,Follow-Up Studies - Abstract
Purpose: To investigate the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the somatropin biosimilar Omnitrope®. Methods: PATRO Children is an ongoing, multicenter, observational, post-marketing surveillance study. Children who received Omnitrope® for any indication were included. Adverse events (AEs) were evaluated in all study participants. Auxological data, including height standard deviation scores (HSDS) and height velocity standard deviation scores (HVSDS), were used to assess effectiveness. In this snapshot analysis, data from the Italian subpopulation up to August 2017 were reported. Results: A total of 291 patients (mean age 10.0 years, 56.0% male) were enrolled at 19 sites in Italy. The mean duration of Omnitrope® treatment was 33.1 ± 21.7 months. There were 48 AEs with a suspected relationship to the study drug (as reported by the investigator) that occurred in 35 (12.0%) patients, most commonly headache, pyrexia, arthralgia, insulin-like growth factor above normal range, abdominal pain, pain in extremity and acute gastroenteritis. There were no confirmed cases of type 1 or type 2 diabetes; however, two patients (0.7%) had impaired glucose tolerance that was considered Omnitrope® related. The mean HSDS increased from − 2.41 ± 0.73 at baseline (n = 238) to − 0.91 ± 0.68 at 6.5 years (n = 10). The mean HVSDS increased from − 1.77 ± 1.38 at baseline (n = 136) to 0.96 ± 1.13 at 6.5 years (n = 10). Conclusions: In this sub-analysis of PATRO Children, Omnitrope® appeared to have acceptable safety and effectiveness in the treatment of in Italian children, which was consistent with the earlier findings from controlled clinical trials.
- Published
- 2020
9. Genetic testing and professional responsibility: the italian experience
- Author
-
Paola Bin, Fabio Policino, Claudia Casella, Adelaide Conti, Paola Delbon, Emanuele Capasso, Pierdomenico Ceccarelli, Piergiorgio Fedeli, Bin, P., Conti, A., Capasso, E., Fedeli, P., Ceccarelli, P., Policino, F., Casella, C., and Delbon, P.
- Subjects
0301 basic medicine ,medicine.diagnostic_test ,business.industry ,Medicine (all) ,Perspective (graphical) ,General Medicine ,Professional responsibility ,genetic testing ,Test (assessment) ,03 medical and health sciences ,Laboratory test ,030104 developmental biology ,0302 clinical medicine ,030220 oncology & carcinogenesis ,professional responsibility ,medicine ,Medicine ,Engineering ethics ,Set (psychology) ,business ,Regular Articles ,Genetic testing - Abstract
Responsibility means responding to the damaging consequences of technical work and in this binding perspective the general principles of guilt in genetic diagnostics and related activities are not different from any other medical performance. Performing a genetic test however, especially when it has predictive characteristics, offers absolutely peculiar technical deontological issues. It is not and should not be considered as a mere habitual laboratory test but as a complex set of interactions that presupposes adequate information as a valid consensus to formalize absolutely in written form.
- Published
- 2018
10. The influence of endoscopic biliary stents on the accuracy of endoscopic ultrasound for pancreatic head cancer staging
- Author
-
Eugenio Giovannini, A Grillo, R Manta, Lauro Bucchi, Giancarlo Caletti, P Fedeli, Stefania Maltoni, Pietro Fusaroli, Fusaroli P, Manta R, Fedeli P, Maltoni S, Grillo A, Giovannini E, Bucchi L, and Caletti G
- Subjects
Endoscopic ultrasound ,Adult ,Male ,medicine.medical_specialty ,Pancreatic disease ,medicine.medical_treatment ,Biliary Stenting ,Endosonography ,Pancreatic cancer ,medicine ,Periampullary cancer ,ENDOSCOPIC ULTRASOUND ,Humans ,Stage (cooking) ,Aged ,Neoplasm Staging ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Stent ,Reproducibility of Results ,Middle Aged ,equipment and supplies ,medicine.disease ,people.cause_of_death ,PANCREATIC CANCER ,digestive system diseases ,Pancreatic Neoplasms ,Biliary tract ,Female ,Stents ,Radiology ,Bile Ducts ,business ,people - Abstract
BACKGROUND AND STUDY AIMS: Biliary stents have been found to interfere with endoscopic ultrasound (EUS) tumor (T) and nodal (N) staging in patients with periampullary cancer. Our aim was to determine whether this also occurs in patients with pancreatic head cancer. PATIENTS AND METHODS: We studied a consecutive series of patients who were undergoing preoperative EUS for diagnosis and staging of suspected pancreatic cancer, some of whom had biliary stents in situ and some of whom did not. The main end point was the uni- and multivariate association of biliary stenting with T and N mis-staging by EUS. The surgical T and N stages were used as gold standards. RESULTS: A total of 65 patients were identified (19 with biliary stents in situ and 46 without). Surgical stage T4 was found more frequently in patients with stents (53 % vs. 22 %, P = 0.014). The T stage by EUS was correct in 85 % of the patients without biliary stents and in 47 % of the patients with stents. The frequency of mis-staging by EUS was significant only among patients with a biliary stent. The distribution by EUS N stage did not differ significantly from the surgical N-stage distribution in the two groups of patients. According to the multivariate analysis, patients with stents were 6.55 times more likely to be incorrectly T staged (95 % confidence interval [CI] 1.69 - 25.49) and 3.71 times more likely to be incorrectly N staged (95 % CI 1.11 - 12.45) than patients without stents. CONCLUSIONS: The results add support to the recommendation that EUS staging of pancreatic head neoplasms should be performed prior to stent placement.
- Published
- 2007
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.