54 results on '"Fraser McConnell"'
Search Results
2. Clinical features and MRI characteristics of presumptive constrictive myelopathy in 27 pugs
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Rita Gonçalves, Raquel Trevail, Andrew Holdsworth, Rodrigo Gutierrez-Quintana, Inés Carrera, Mark Lowrie, Filipa Lourinho, Carles Morales, and J. Fraser McConnell
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Male ,medicine.medical_specialty ,040301 veterinary sciences ,Dura mater ,Constriction, Pathologic ,Spinal Cord Diseases ,030218 nuclear medicine & medical imaging ,0403 veterinary science ,03 medical and health sciences ,Myelopathy ,0302 clinical medicine ,Dogs ,Spinal cord compression ,medicine ,Animals ,Dog Diseases ,Paresis ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,04 agricultural and veterinary sciences ,medicine.disease ,Spinal cord ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Dysplasia ,Female ,Radiology ,medicine.symptom ,Subarachnoid space ,business - Abstract
Constrictive myelopathy has been described in pugs with paraparesis and is characterized by fibrous connective and granulation tissue within the dura mater causing spinal cord compression and focal gliosis. An association between constrictive myelopathy and caudal articular process (CAP) dysplasia is suspected; however, some studies have reported CAP dysplasia as an incidental finding. The imaging appearance of constrictive myelopathy is currently limited to a small number of cases. The aim of this multicenter, retrospective, descriptive study was to detail the magnetic resonance imaging (MRI) characteristics and to correlate these with clinical signs of presumptive constrictive myelopathy in pugs. Medical databases from five veterinary referral hospitals were reviewed to identify pugs with pelvic limb ataxia and paresis, that had a complete record of signalment, neurological examination, and MRI of the thoracolumbar spinal cord. The exclusion criteria were pugs with other conditions, such as unequivocal subarachnoid diverticula, hemivertebrae causing vertebral canal stenosis, intervertebral disc extrusions/protrusions, and multifocal/diffuse lesions. Twenty-seven pugs met the inclusion criteria. All cases were ambulatory with paraparesis and ataxia. Nearly 60% were incontinent. Magnetic resonance imaging revealed a focal myelopathy in all cases showing one or more of the following lesions: CAP dysplasia (25/27), focal subarachnoid space irregular margination (26/27) with circumferential or dorsal contrast enhancement (10/12), and a symmetric V-shaped ventral extradural lesion (23/27). This study describes specific MRI features of pugs with presumptive constrictive myelopathy, which authors hypothesize to be a consequence of chronic micro-motion. Our results may help in diagnosing and subsequently treating this condition, which may warrant vertebral stabilization.
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- 2019
3. Advanced Imaging
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Simon Platt and J. Fraser McConnell
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medicine.medical_specialty ,business.industry ,Intracranial surgery ,medicine ,Radiology ,business - Published
- 2017
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4. Successful surgical management of an Escherichia coli epidural-subdural abscess secondary to sino-rhinotomy
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Richard Coe, Fraser McConnell, Alistair Freeman, Daniel Sanchez-Masian, and Angharad B. Simlett-Moss
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Male ,medicine.medical_specialty ,Epidural abscess ,040301 veterinary sciences ,medicine.medical_treatment ,Brain herniation ,0403 veterinary science ,03 medical and health sciences ,0302 clinical medicine ,Dogs ,Postoperative Complications ,Midline shift ,medicine ,Escherichia coli ,Animals ,Dog Diseases ,Abscess ,Escherichia coli Infections ,Intracranial pressure ,Empyema, Subdural ,General Veterinary ,business.industry ,Glasgow Coma Scale ,030208 emergency & critical care medicine ,04 agricultural and veterinary sciences ,medicine.disease ,Empyema ,Surgery ,Anti-Bacterial Agents ,Epidural Abscess ,Decompressive craniectomy ,business - Abstract
Objective To describe a case of successful management of epidural-subdural abscess and severe meningitis with secondary brain herniation in a dog. Case summary A rhino-sinusotomy was performed in a 3-year-old mixed-breed dog for management of refractory sinonasal aspergillosis. Initial recovery was good, but the dog became acutely stuporous 36 hours after surgery. Evidence of increased intracranial pressure with brain herniation and midline shift secondary to an epidural abscess was observed on magnetic resonance imaging. Decompressive craniectomy and drainage of the abscess was performed. Intensive nursing care and physiologic support was performed with consciousness returning 7 days after initial stupor. The dog was discharged 14 days after craniectomy and was ambulatory with support. New/unique information provided Intracranial abscesses are rarely described in dogs and few had a successful outcome reported. All previous reports have been of brain abscesses or empyema, rather than a combination of epidural and subdural abscessation. Additionally, the process of sino-rhinotomy for management of aspergillosis has not been previously linked to intracranial abscess formation. To the authors' knowledge, this is the first report of successful management of an epidural-subdural abscess and suggests that even with cases with low modified Glasgow Coma Scale scores outcome may be positive.
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- 2017
5. MRI, CT and histopathological findings in a cat with hypovitaminosis A
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Emanuele Ricci, Fraser McConnell, Irene Espadas, and Daniel Sanchez-Masian
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Hyperostosis ,Pathology ,medicine.medical_specialty ,General Veterinary ,medicine.diagnostic_test ,040301 veterinary sciences ,business.industry ,Tentorium cerebelli ,Meninges ,Optic chiasm ,Magnetic resonance imaging ,04 agricultural and veterinary sciences ,Anatomy ,medicine.disease ,0403 veterinary science ,White matter ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,medicine ,Hyperostosis frontalis interna ,business ,Spongiosis - Abstract
An adult, male, domestic longhair cat was evaluated for chronic progressive visual impairment and lethargy. Neurological abnormalities localised to the cerebellum/central vestibular system, and optic chiasm/retinas and/or optic nerves were present on clinical examination. MRI and CT studies showed diffuse hyperostosis with thickening of the calvarium and tentorium cerebelli causing compression and distortion of the brain. Biochemical testing showed low plasma retinol levels at 0.1 μmol/l (0.86–2.2). Postmortem examination showed reduction in volume of the frontal lobes secondary to diffuse skull hyperostosis. Microscopically, there were mild white matter spongiosis affecting the corona radiata and optic nerves and multiple small plaque-like thickening of the meninges. This is the first case report to provide a comprehensive clinical, diagnostic imaging and pathological details of hypovitaminosis A in a cat.
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- 2017
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6. COMPUTED TOMOGRAPHIC FINDINGS IN 15 DOGS WITH EOSINOPHILIC BRONCHOPNEUMOPATHY
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Christopher R. Lamb, J. Fraser McConnell, Richard Lam, and Luis Mesquita
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Pathology ,medicine.medical_specialty ,Multiple Pulmonary Nodules ,Bronchiectasis ,Lung ,General Veterinary ,business.industry ,respiratory system ,medicine.disease ,Lymphatic disease ,medicine.anatomical_structure ,Eosinophilic ,Parenchyma ,medicine ,Eosinophilia ,Radiology ,medicine.symptom ,business ,Pulmonary Eosinophilia - Abstract
Eosinophilic bronchopneumopathy is a disease characterized by the infiltration of the lung and bronchial mucosa by eosinophils. The aim of the present study was to describe the CT findings in a large series of dogs with confirmed diagnosis of eosinophilic bronchopneumopathy. Computed tomographic scans of 15 dogs with confirmed diagnosis of eosinophilic bronchopneumopathy were evaluated retrospectively by two boarded radiologists who reached a consensus. Abnormalities were identified in 14/15 (93%) dogs, including pulmonary parenchymal abnormalities in 14/15 (93%) dogs, bronchial wall thickening in 13 (87%) dogs, which was considered marked in eight (53%), plugging of the bronchial lumen by mucus/debris in 11 (73%) dogs, and bronchiectasis in nine (60%) dogs. Pulmonary nodules were identified in 5/15 (33%) dogs including one dog with a mass. All dogs with a nodular lung pattern had additional abnormalities. Lymphadenopathy was present in 10 dogs (67%). Lesions associated with eosinophilic bronchopneumopathy are variable and heterogeneous and encompass a wider variety of computed tomographic features than reported previously. Computed tomographic images were abnormal in the majority of affected dogs, hence CT is a useful modality to characterize the nature and distribution of thoracic lesions in dogs with eosinophilic bronchopneumopathy.
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- 2014
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7. Fundamentals in diagnostic imaging
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Andrew Holloway and Fraser McConnell
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medicine.medical_specialty ,business.industry ,General Chemical Engineering ,Radiography ,Medical imaging ,medicine ,Radiology ,business - Abstract
The new edition of the BSAVA Manual of Canine and Feline Radiography and Radiology focuses on the basic principles of radiology to present a systematic approach to interpretation.
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- 2013
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8. COMPARISON BETWEEN SHOULDER COMPUTED TOMOGRAPHY AND CLINICAL FINDINGS IN 89 DOGS PRESENTED FOR THORACIC LIMB LAMENESS
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B. J. Keeley, Thomas W. Maddox, J. Fraser McConnell, and C. May
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medicine.medical_specialty ,Supraspinatus muscle ,General Veterinary ,business.industry ,Retrospective cohort study ,Osteoarthritis ,Odds ratio ,medicine.disease ,Tendon ,medicine.anatomical_structure ,Lameness ,Osteochondrosis ,Medicine ,Clinical significance ,Radiology ,business - Abstract
Computed tomography (CT) is an established technique for detecting shoulder lesions in dogs, however the clinical significance of shoulder CT lesions often remains uncertain. The purposes of this retrospective study were to describe the prevalence of CT lesions in both shoulder joints for 89 dogs presenting with thoracic limb lameness and to compare CT lesions with clinical characteristics. For all included dogs, results of a full orthopedic examination, other diagnostic tests, and signalment data were available in medical records. Multilevel, multivariable logistic regression was used to test clinical significance of the most prevalent CT lesions and determine factors associated with their presence. Computed tomographic lesions were detected in one or both shoulder joints for 51/89 dogs (57.3%). Mineralization of one or more surrounding peri-articular soft-tissue structures was identified in 31.5% of dogs, with supraspinatus muscle/tendon mineralization being the most frequently identified (24.7%). The prevalence of humeral head osteochondrosis was 9 and 21.3% of dogs had shoulder osteoarthritis. Border collies (odds ratio [OR] 9.3; 95% CI 1.39-62.1, P = 0.02) and dogs with shoulder pain (OR 4.3; 95% CI 1.08-17.1, P = 0.04) had increased risk of osteochondrosis lesions. Border collies (OR 8.4; 95% CI 1.27-55.6; P = 0.03) and older animals (OR 1.04; 95% CI 1.02-1.1, P < 0.001) had increased risk of osteoarthritis lesions. Female entire dogs had an increased risk of supraspinatus mineralization lesions (OR 6.8; 95% CI 1.55-29.5, P = 0.01). Findings indicated that shoulder CT lesions are common in dogs with thoracic limb lameness, and that some CT lesions are not associated with shoulder pain.
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- 2013
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9. Clinical and clinicopathologic abnormalities in young dogs with acquired and congenital portosystemic shunts: 93 cases (2003–2008)
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Alison Collings, Rachel Burrow, Mary R Trehy, Fiona Adam, Nat Whitley, Alexander J. German, J. Fraser McConnell, and Penny Watson
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Male ,Aging ,Pediatrics ,medicine.medical_specialty ,Neurologic Signs ,Physical examination ,symbols.namesake ,Dogs ,Ascites ,Animals ,Medicine ,Dog Diseases ,Fisher's exact test ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Significant difference ,Retrospective cohort study ,Confidence interval ,Portal System ,Diarrhea ,symbols ,Female ,medicine.symptom ,business - Abstract
Objective—To determine whether clinical and clinicopathologic data could assist differentiation of congenital portosystemic shunts (CPSSs) from acquired portosystemic shunts (APSSs) in young dogs. Design—Retrospective case series. Animals—Dogs < 30 months of age with CPSSs (n = 62) or APSSs (31). Procedures—Medical records from 3 referral centers identified 31 dogs with APSSs and 62 dogs with CPSSs diagnosed from July 2003 to July 2008. Signalment, clinical signs, physical examination, and clinicopathological data were recorded, and statistical analyses were performed to determine differences between groups. Results—Univariable analysis showed APSS patients were older, heavier, and in poorer body condition, compared with CPSS patients. In CPSS patients, diarrhea was less prevalent, and neurologic signs were more prevalent. Ascites was more prevalent in APSS (Fisher exact test; OR, 50.2; 95% confidence interval [CI], 6.2 to 409.7), with no significant difference in albumin concentration between groups. The logistic regression model used to assess clinicopathological parameters showed lower Hct (OR, 1.42 × 10−12; 95% CI, 1.42 × 10−17 to 4.0 × 10−6), higher mean corpuscular volume (OR, 1.27; 95% CI, 1.08 to 1.50), and higher alanine aminotransferase concentrations (OR, 1.005; 95% CI, 1.001 to 1.009) were more likely in APSS patients. Conclusions and Clinical Relevance—Several clinicopathologic differences between dogs with congenital and acquired shunts were identified; however, assessed alone, these would be unlikely to enable differentiation between the 2 conditions. Awareness of the rarity of ascites in CPSS cases should prompt recognition of a likely diagnosis of APSS, allowing the veterinarian to target further diagnostics and counsel the owner appropriately.
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- 2012
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10. UNIQUE TOPOGRAPHIC DISTRIBUTION OF GREYHOUND NONSUPPURATIVE MENINGOENCEPHALITIS
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Robert E. Shiel, Simon L. Priestnall, E. Terzo, Ken C. Smith, Sebastien Behr, J. Fraser McConnell, John J. Callanan, Catherine M. Nolan, and Hester McAllister
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0303 health sciences ,Pathology ,medicine.medical_specialty ,General Veterinary ,medicine.diagnostic_test ,040301 veterinary sciences ,Cerebrum ,business.industry ,Meningoencephalitis ,Magnetic resonance imaging ,04 agricultural and veterinary sciences ,Inversion recovery ,Anatomy ,Fluid-attenuated inversion recovery ,medicine.disease ,Mr imaging ,0403 veterinary science ,03 medical and health sciences ,medicine.anatomical_structure ,medicine ,Olfactory Lobe ,T2 weighted ,business ,030304 developmental biology - Abstract
Greyhound nonsuppurative meningoencephalitis is an idiopathic breed-associated fatal meningoencephalitis with lesions usually occurring within the rostral cerebrum. This disorder can only be confirmed by postmortem examination, with a diagnosis based upon the unique topography of inflammatory lesions. Our purpose was to describe the magnetic resonance (MR) imaging features of this disease. Four Greyhounds with confirmed Greyhound nonsuppurative meningoencephalitis were evaluated by MR imaging. Lesions predominantly affected the olfactory lobes and bulbs, frontal, and frontotemporal cortical gray matter, and caudate nuclei bilaterally. Fluid attenuation inversion recovery (FLAIR) and T2 weighted spin-echo (T2W) sequences were most useful to assess the nature, severity, extension, and topographic pattern of lesions. Lesions were predominantly T2-hyperintense and T1-isointense with minimal or absent contrast enhancement.
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- 2012
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11. IMAGING DIAGNOSIS-VENTRICULO-PERITONEAL SHUNT ASSOCIATED INFECTION IN A DOG
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Simon R. Platt, Lara Matiasek, and J. Fraser McConnell
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Pathology ,medicine.medical_specialty ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Ventricular system ,Fluid-attenuated inversion recovery ,medicine.disease ,Hyperintensity ,Hydrocephalus ,Shunt (medical) ,Shunting ,medicine ,Complication ,business - Abstract
Ventriculo-peritoneal shunting is a surgical treatment for hydrocephalus. Complications of this procedure are not well described in dogs. The most common complication in humans is infection, which can be fatal if not diagnosed and treated quickly. We describe the magnetic resonance (MR) imaging characteristics of a shunt-associated cerebral infection in a dog. The MR features of the infection included hyperintensity of the lining of the ventricular system visible on a T2-weighted FLAIR sequence and marked linear contrast enhancement of the ependymal layer on T1-weighted sequences, similar to that described in people.
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- 2011
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12. Balloon dilation of an imperforate cor triatriatum dexter in a Golden Retriever with concurrent double-chambered right ventricle and subsequent evaluation by cardiac magnetic resonance imaging
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Joanna Dukes-McEwan, J. Fraser McConnell, Sonja Fonfara, David Killick, Mike W.S. Martin, and J. López-Alvarez
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Heart Defects, Congenital ,Male ,medicine.medical_specialty ,Physiology ,Cor triatriatum dexter ,Golden Retriever ,Catheterization ,Dogs ,Cardiac magnetic resonance imaging ,Internal medicine ,medicine ,Animals ,Dog Diseases ,Diuretics ,Coronary sinus ,Heart Failure ,General Veterinary ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Ventricle ,Heart failure ,Balloon dilation ,Cardiology ,Radiology ,CTD ,business - Abstract
A 12-week-old male Golden Retriever was presented with signs of right-sided congestive heart failure and a grade V/VI left craniosternal systolic murmur. Echocardiography identified a double-chambered right ventricle and dilated coronary sinus (CS) running into an inter-atrial chamber. This was confirmed to be an imperforate cor triatriatum dexter (CTD) by selective angiographic studies. To the authors’ knowledge this is the first case reported of imperforate CTD successfully treated by membranostomy and balloon dilation. Cardiac MRI confirmed the echocardiographic and angiographic findings and provided a more precise understanding of the venous abnormalities.
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- 2011
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13. Arrhythmias and transient changes in cardiac function after topical administration of one drop of phenylephrine 10% in an adult cat undergoing conjunctival graft
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Elizabeth A Leece, J. Fraser McConnell, and Paolo Franci
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Lidocaine ,Administration, Topical ,Cat Diseases ,Conjunctival Diseases ,Electrocardiography ,Phenylephrine ,Heart Rate ,Heart rate ,medicine ,Animals ,Vasoconstrictor Agents ,Pulse ,General Veterinary ,business.industry ,Arrhythmias, Cardiac ,Phenylephrine Hydrochloride ,medicine.disease ,Blood pressure ,Isoflurane ,Bigeminy ,Anesthesia ,Cats ,Female ,business ,Propofol ,Conjunctiva ,medicine.drug - Abstract
History A 2-year-old, entire female, Somali cat weighing 3.8 kg was admitted for a conjunctival graft on the right eye, for treatment of an acute descemetocele. Medetomidine 4.2 μg kg −1 and methadone 0.2 mg kg −1 were administered by intramuscular injection as preanaesthetic medication. Anaesthesia was induced using diazepam 0.26 mg kg −1 and propofol 4 mg kg −1 administered by intravenous (IV) injection. Following endotracheal intubation, anaesthesia was maintained with isoflurane delivered in oxygen (1 L minute −1 ) and nitrous oxide (2 L minute −1 ) via a non-rebreathing system. Twenty minutes after induction of anaesthesia, one drop of a 10% phenylephrine hydrochloride solution was administered topically to the right eye. Physical examination After phenylephrine administration, a decrease in heart rate (from 95 to 80 beats minute −1 ) and an increase in arterial blood pressure occurred. The pulse then became difficult to palpate manually and multifocal ventricular premature contractions were observed on the electrocardiogram. Management Nitrous oxide was discontinued and the isoflurane vaporizer setting was decreased from 1.5% to 0.5%. Lidocaine 1 mg kg −1 IV was administered, this resulted in ventricular bigeminy. The quality of the femoral pulse improved and was regular in rhythm and character. Surgery was completed as fast as possible. The bigeminy progressively disappeared and before disconnecting the cat from the breathing system, there was a normal sinus rhythm with a heart rate of 85 beats minute −1 . Follow-up Echocardiography was performed during recovery and showed mitral and aortic valve insufficiency and dilation of the left ventricle, suggesting a reduction in systolic function. Echocardiography was repeated the following day and was normal. Conclusions In order to diminish the potential for cardiovascular sequelae associated with systemic absorption of ocular phenylephrine, less concentrated solutions, smaller drop size or different instillation techniques should be considered for topical use in small patients.
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- 2011
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14. Clinical and topographic magnetic resonance imaging characteristics of suspected thalamic infarcts in 16 dogs
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J. Fraser McConnell, Laurent Garosi, Inés Carrera, Rita Gonçalves, Peter M. Smith, Jacques Penderis, University of Zurich, and Gonçalves, R
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Male ,Cerebellum ,Pathology ,medicine.medical_specialty ,10253 Department of Small Animals ,Internal capsule ,3400 General Veterinary ,Thalamus ,Brain Ischemia ,Lesion ,Midbrain ,Dogs ,medicine ,Animals ,Dog Diseases ,Stroke ,General Veterinary ,Proprioception ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Anatomy ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,570 Life sciences ,biology ,Female ,Animal Science and Zoology ,1103 Animal Science and Zoology ,medicine.symptom ,business - Abstract
Sixteen dogs with acute-onset, non-progressive signs of brain dysfunction and magnetic resonance imaging (MRI) characteristics compatible with thalamic infarction are described. Topographically the MRI lesions could be grouped in three thalamic regions, namely, paramedian (8/16), extensive dorsal (5/16) and ventrolateral (3/16). Paramedian lesions resulted in signs typical of vestibular dysfunction. Extensive dorsal lesions were associated with vestibular ataxia, circling and contralateral menace response deficits. Ventrolateral lesions resulted in circling and contralateral proprioceptive deficits. In several dogs, regions other than the thalamus were also affected: four extended into the midbrain; six extended to the internal capsule, and two dogs had a second lesion in the cerebellum. Three clinical syndromes were identified in association with thalamic infarction. These signs varied somewhat, most likely because lesions were not confined to specific nuclear boundaries and involved different combinations of thalamic nuclei.
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- 2011
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15. MAGNETIC RESONANCE IMAGING FEATURES OF DISCOSPONDYLITIS IN DOGS
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Inés Carrera, Rita Gonçalves, Fraser McConnell, and Martin Sullivan
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Subluxation ,medicine.medical_specialty ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Radiography ,Soft tissue ,Magnetic resonance imaging ,medicine.disease ,Hyperintensity ,Epidural space ,Intervertebral disk ,medicine.anatomical_structure ,Spinal cord compression ,Medicine ,Radiology ,business - Abstract
The diagnosis of discospondylitis is based mainly on diagnostic imaging and laboratory results. Herein, we describe the magnetic resonance imaging (MRI) findings in 13 dogs with confirmed discospondylitis. In total there were 17 sites of discospondylitis. Eleven (81.1%) of the dogs had spinal pain for >3 weeks and a variable degree of neurologic signs. Two dogs had spinal pain and ataxia for 4 days. Radiographs were available in nine of the dogs. In MR images there was always involvement of two adjacent vertebral endplates and the associated disk. The involved endplates and adjacent marrow were T1-hypointense with hyperintensity in short tau inversion recovery (STIR) images in all dogs, and all dogs also had contrast enhancement of endplates and paravertebral tissues. The intervertebral disks were hyperintense in T2W and STIR images and characterized by contrast enhancement in 15 sites (88.2%). Endplate erosion was present in 15 sites (88.2%) and was associated with T2-hypointense bone marrow adjacent to it. In two sites (11.8%) endplate erosion was not MR images or radiographically. The vertebral bone marrow in these sites was T2-hyperintense. Epidural extension was conspicuous in postcontrast images at 15 sites (88.2%). Spinal cord compression was present at 15 sites (88.2%), and all affected dogs had neurologic signs. Subluxation was present in two sites (11.8%). MRI shows characteristic features of discospondylitis, and it allows the recognition of the exact location and extension (to the epidural space and paravertebral soft tissues) of the infection. Furthermore, MRI increases lesion conspicuity in early discospondylitis that may not be visualized by radiography.
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- 2010
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16. Association of clinical and magnetic resonance imaging findings with outcome in dogs with presumptive acute noncompressive nucleus pulposus extrusion: 42 cases (2000–2007)
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Ruth Dennis, Luisa De Risio, Vicki J. Adams, and Fraser McConnell
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Male ,medicine.medical_specialty ,Strenuous exercise ,Neurologic Signs ,Diagnosis, Differential ,Myelopathy ,Dogs ,Acute onset ,Predictive Value of Tests ,medicine ,Animals ,Dog Diseases ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Pancreatic Ducts ,Magnetic resonance imaging ,Prognosis ,medicine.disease ,Spinal cord ,Magnetic Resonance Imaging ,Treatment Outcome ,medicine.anatomical_structure ,Acute Disease ,Female ,Radiology ,business ,Nucleus ,Intervertebral Disc Displacement ,Mri findings - Abstract
Objective—To assess associations of severity of neurologic signs (neurologic score), involvement of an intumescence, and findings of magnetic resonance imaging (MRI) with interval to recovery and outcome in dogs with presumptive acute noncompressive nucleus pulposus extrusions. Design—Retrospective case series. Animals—42 dogs with presumptive acute noncompressive nucleus pulposus extrusions. Procedures—Medical records and magnetic resonance (MR) images of dogs evaluated from 2000 through 2007 were reviewed. Inclusion criteria were acute onset of nonprogressive myelopathy following trauma or strenuous exercise, MRI of the spine performed within 7 days after onset, MRI findings consistent with acute noncompressive nucleus pulposus extrusions, and complete medical records and follow-up. Results—Clinical neuroanatomic localization of lesions was to the C1-C5 (n = 6), C6-T2 (6), T3-L3 (28), and L4-S3 (2) spinal cord segments. Median neurologic score was 3.5. Median duration of follow-up was 804 days (range, 3 to 2,134 days) after onset of neurologic signs. Outcome was successful in 28 (67%) dogs and unsuccessful in 14 (33%) dogs. Severity of neurologic signs, extent of the intramedullary hyperintensity on sagittal and transverse T2-weighted MR images, and detection of intramedullary hypointensity on GRE images were all associated with outcome on univariate analysis. Results of multivariate analysis suggested that maximal cross-sectional area of the intramedullary hyperintensity on transverse T2-weighted MR images was the best predictor of outcome. Conclusions and Clinical Importance—Clinical and MRI findings can help predict outcome in dogs with acute noncompressive nucleus pulposus extrusions.
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- 2009
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17. Emerging canine angiostrongylosis in northern England: five fatal cases
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E. G. Valentine, A. Mas, Fraser McConnell, Y. Yamakawa, D. Denk, B. Tatton, Joanna Dukes-McEwan, John McGarry, N. Macdonald, Jonathan M. Williams, J. Wayne, and Udo Hetzel
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Male ,Pediatrics ,Pathology ,medicine.medical_specialty ,Angiostrongylus vasorum ,Foxes ,Chronic coughing ,Disease ,Disease Vectors ,Communicable Diseases, Emerging ,Dogs ,Fatal Outcome ,South east ,medicine ,Animals ,Helminths ,Dog Diseases ,Angiostrongylus ,Lung ,Strongylida Infections ,General Veterinary ,biology ,business.industry ,Incidence (epidemiology) ,Syncope (genus) ,Brain ,Prolonged bleeding ,General Medicine ,biology.organism_classification ,Nematode parasite ,England ,Female ,business - Abstract
Angiostrongylus vasorum is a metastrongylid nematode parasite that resides in the pulmonary arteries and right ventricle of dogs and other canids. Since its discovery in France in 1866 by Baillet (Rosen and others 1970), A vasorum has been reported in dogs in Europe (Denmark, France, Germany, Ireland, Italy, Spain, Sweden, Switzerland, Turkey and the UK), Africa (Uganda), South America (Brazil and Columbia) and Canada (Newfoundland) (Brennan and others 2004, Bourque and others 2008, Traversa and Guglielmini 2008). It is widely assumed that foxes act as a reservoir of infection for dogs and a recent study has shown that infection is endemic in foxes in areas of the UK where there is a high incidence of A vasorum infection in canines (Morgan and others 2008). In the UK, canine A vasorum infection was first reported in Cornwall in 1982 (Simpson and Neal 1982) with further cases appearing in South Wales in 1987 (Patteson and others 1987, Trees 1987). In the past decade, the disease has been increasingly diagnosed in dogs in the south east of England (Chapman and others 2004) and recently an autochthonous case was reported in Glasgow (J. Dukes-McEwan, personal communication). There have so far been no published cases of canine A vasorum infection in northern England, and infection has been absent in foxes (Morgan and others 2008). Although clinical signs in association with A vasorum infection in dogs can be variable, they typically represent three main syndromes: cardiorespiratory signs, coagulopathies and neurological dysfunction (Koch and Willesen 2008). Dogs with cardiorespiratory signs present with a history that may include chronic coughing, exercise intolerance, syncope, dyspnoea and tachypnoea (Bolt and others 1994), whereas the coagulopathies can result in anaemia, subcutaneous haematomas, internal haemorrhages and prolonged bleeding from wounds or after surgery (Ramsey and others 1996, …
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- 2009
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18. The Use of Ultrasonography in Small Animal Veterinary Practice
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Fraser McConnell
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Veterinary medicine ,Radiological and Ultrasound Technology ,business.industry ,Interpretation (philosophy) ,Small animal ,Medicine ,Radiology, Nuclear Medicine and imaging ,Ultrasonography ,Case management ,business - Abstract
Ultrasonography is widely used in veterinary practices and forms an integral part of case management for many diseases. Patient size combined with breed and species variations can cause problems in interpretation and image quality. This article reviews the ultrasongraphic procedures commonly used in small animal veterinary practice.
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- 2008
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19. MAGNETIC RESONANCE IMAGING FEATURES OF SPINAL EPIDURAL EMPYEMA IN FIVE DOGS
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Ruth Dennis, Simon R. Platt, Alberta De Stefani, Fraser McConnell, Laurent Garosi, and Francisco J. Llabres Diaz
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Male ,Pathology ,medicine.medical_specialty ,Diagnosis, Differential ,Lesion ,Myelopathy ,Dogs ,Animals ,Medicine ,Dog Diseases ,Empyema ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,medicine.disease ,Magnetic Resonance Imaging ,Epidural space ,Peripheral ,medicine.anatomical_structure ,Spinal epidural ,Female ,Radiology ,Differential diagnosis ,medicine.symptom ,business - Abstract
Spinal epidural empyema is defined an accumulation of purulent material in the epidural space of the vertebral canal. Spinal epidural empyema should be considered as a differential diagnosis in dogs with pyrexia, spinal pain, and rapidly progressing myelopathy. Magnetic resonance (MR) imaging is the imaging test of choice in humans. Here, we describe the MR imaging features of five dogs with confirmed spinal epidural empyema. The epidural lesions appeared as high or mixed signal masses in T2-weighted (T2W) images. Increased signal within the spinal cord gray matter at the site of the lesion was detected in T2W images in all dogs. Two patterns of enhancement were detected on postcontrast T1-weighted (T1W) images. Mild to moderate peripheral enhancement was seen in three dogs and a diffuse pattern of enhancement was seen in one. Discospondylitis was identified in three dogs on T1W postcontrast images. Decompressive spinal surgery was performed in all dogs. Bacteria isolated from the abnormal epidural tissue were Enterobacter cloacae, coagulase-positive Staphylococci, Pasteurella multocida, and Escherichia coli. In one dog bacteria were not isolated. These MR imaging features, along with appropriate clinical signs, can allow prompt diagnosis and appropriate treatment planning.
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- 2008
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20. Basics of musculoskeletal magnetic resonance imaging
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J. Fraser McConnell
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Soft tissue contrast ,Modality (human–computer interaction) ,Nuclear magnetic resonance ,medicine.diagnostic_test ,Computer science ,medicine ,Magnetic resonance imaging ,Mr studies - Abstract
MRI is a cross-sectional imaging modality, which uses the spins of hydrogen protons to generate anatomical images and, with some techniques, functional information. One of the advantages of MRI over CT is that in MR studies no ionizing radiation is used, but its main advantage is its superior soft tissue contrast when compared with all other modalities. This chapter explains terminology; fundamental principles of magnetic resonance imaging; indications; safety; technique; contrast media; protocols; principles of interpretation; abnormalities, artefacts and pitfalls.
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- 2016
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21. Wooden orbital foreign body in a Weimaraner
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Claudia Hartley, Ross Doust, and J. Fraser McConnell
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genetic structures ,Exophthalmos ,Staphylococcus ,Ophthalmologic Surgical Procedures ,Eye Infections, Bacterial ,Diagnosis, Differential ,Dogs ,Orbital Diseases ,Animals ,Medicine ,Dog Diseases ,Ultrasonography ,Pterygopalatine fossa ,Clostridium ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Foreign-Body Reaction ,Echogenicity ,Magnetic resonance imaging ,Anatomy ,medicine.disease ,Magnetic Resonance Imaging ,Wood ,eye diseases ,Pedigree ,Posterior segment of eyeball ,medicine.anatomical_structure ,Zygomatic arch ,sense organs ,Foreign body ,medicine.symptom ,business ,Orbit (anatomy) - Abstract
A 2-year-old, male Weimaraner presented with acute-onset nonaxial exophthalmos with dorsal deviation of the left globe. Periorbital swelling, pain and a profuse purulent ocular discharge were present on the left side. A draining sinus tract was present in the left ventral conjunctival fornix and another in the left pterygopalatine fossa. The right eye was normal on complete ophthalmic examination. Orbital ultrasonography revealed large, double, linear, parallel echogenic bands with shadowing present in the ventrolateral aspect of the left orbit suggestive of a foreign body. Deformation of the posterior segment was also present. Removal of the orbital foreign body was attempted under ultrasound guidance via the discharging sinuses in the ventral conjunctival fornix and the pterygopalatine fossa. Neither approach was successful; however, a small amount of organic material was retrieved confirming the diagnosis of orbital foreign body. Magnetic resonance imaging (MRI) revealed a linear foreign body of 8 x 1.5 x 0.8 cm extending from the orbit to the level of the oropharynx. A modified lateral orbitotomy with zygomatic arch resection on the left side allowed removal of the wooden foreign body.
- Published
- 2007
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22. Magnetic Resonance Imaging Findings and Clinical Associations in 52 Dogs with Suspected Ischemic Myelopathy
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Fraser McConnell, Vicki J. Adams, Simon R. Platt, Luisa De Risio, and Ruth Dennis
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medicine.medical_specialty ,medicine.diagnostic_test ,General Veterinary ,business.industry ,Spinal Cord Ischemia ,Medical record ,Retrospective cohort study ,Magnetic resonance imaging ,Spinal cord ,medicine.disease ,Magnetic Resonance Imaging ,Sagittal plane ,Lesion ,Myelopathy ,medicine.anatomical_structure ,Cerebrospinal fluid ,Dogs ,medicine ,Animals ,Radiology ,Dog Diseases ,medicine.symptom ,business ,Retrospective Studies - Abstract
Background: The magnetic resonance imaging (MRI) features of ischemic myelopathy have been described in the human literature and in a small number of cases in the veterinary literature. Hypothesis: The aims of this study were to identify associations among MRI findings, timing of imaging, and presenting neurologic deficits in a large series of dogs with a presumptive diagnosis of ischemic myelopathy. Animals and Methods: The medical records and MR images of dogs with a presumptive diagnosis of ischemic myelopathy (2000–2006) were reviewed retrospectively. Inclusion criteria were acute onset of nonprogressive and nonpainful myelopathy, 1.5-tesla MRI of the spine performed within 7 days of onset, and complete medical records and follow-up information. Presumptive diagnosis was based on history, as well as clinical, MRI, and cerebrospinal fluid (CSF) findings. The extent of the lesion on MRI was assessed as the following: (1) the ratio between the length of the hyperintense area on sagittal T2-weighted images and the length of C6 or L2 vertebral body, and (2) the maximal cross-sectional area of the hyperintense area on transverse T2-weighted images as a percentage of cross-sectional area of the spinal cord. Results: Fifty-two dogs met the inclusion criteria. MRI findings were abnormal in 41 dogs and normal in 11 dogs. The presence of MRI abnormalities was not significantly associated with the timing of imaging (P= .3) but was associated with ambulatory status on presentation (P= .04). Severity of signs on presentation was associated with extent of the lesion on MRI (P= .02). Conclusion and Clinical Importance: The severity of signs on presentation is associated with the presence and the extent of the lesion on MRI.
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- 2007
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23. Perspectives on Digital Technology in a Remote School Community
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Julia Davidson, Irene McQueen, Fraser McConnell, and J Eric Wilkinson
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ComputingMilieux_COMPUTERSANDEDUCATION - Abstract
The present article is based on a qualitative evaluation of the use of digital technology in a remote secondary school in the Scottish Highlands. The attitudes of teachers and pupils to the use of digital technology and the underlying tensions between formal and informal educational practices are central concerns addressed in this paper. The project was for one-year and designed to facilitate the embedding of digital technology across the curriculum. Some of the benefits of participating in the project, according to the pupils, included an improvement in their ability to work successfully with others, independently from the teacher, and the development of their skills in creating moving images in both curricular and extra-curricular activities. Most participating teachers commented that they had improved their own ICT skills. In conclusion, some complex issues are raised in connection with schools in isolated communities.
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- 2007
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24. How can MRI not give me an answer?
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Fraser McConnell
- Published
- 2015
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25. Canine internal medicine: internal medic, diagnostic imager and clinical pathologist
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Rob Foale, Fraser McConnell, and Andy Torrance
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medicine.medical_specialty ,business.industry ,medicine ,Medical physics ,business - Published
- 2015
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26. MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF CANINE INFLAMMATORY MYOPATHIES IN THREE DOGS
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Simon R. Platt, G. Diane Shelton, Jane Ladlow, J. Fraser McConnell, Alberta De Stefani, and Laurent Garosi
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Male ,medicine.medical_specialty ,Pathology ,Contrast Media ,Electromyography ,Diagnosis, Differential ,Inflammatory myopathy ,Dogs ,Predictive Value of Tests ,Biopsy ,medicine ,Animals ,Dog Diseases ,Muscle biopsy ,Myositis ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Muscle inflammation ,Image Enhancement ,medicine.disease ,Magnetic Resonance Imaging ,Signal on ,Contrast medium ,Female ,Radiology ,business - Abstract
In humans affected with inflammatory myopathies, regions of altered signal intensity are found on magnetic resonance (MR) images of affected muscles. Although electromyography (EMG) is more practical for muscle disease evaluation, and a muscle biopsy is the only manner in which a definitive diagnosis can be made, MR imaging has proven useful if a specific anatomic localization is difficult to achieve. Three dogs with focal inflammatory myopathy diagnosed with the assistance of MR imaging are discussed and the findings are compared with those found in humans. MR images of the affected muscles in each dog were characterized by diffuse and poorly marginated abnormal signal on T1- and T2-weighted images. Marked enhancement was noted in these muscles after contrast medium administration. An inflammatory myopathy was confirmed histologically in all three dogs. A good association existed between the MR images and muscle inflammation identified histopathologically. MR imaging may be a useful adjunctive procedure for canine inflammatory myopathies.
- Published
- 2006
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27. Intramedullary Intervertebral Disk Extrusion in a Cat
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J. Fraser McConnell and Laurent Garosi
- Subjects
Male ,Lumbar Vertebrae ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Radiography ,Magnetic resonance imaging ,Anatomy ,Cat Diseases ,Spinal cord ,Magnetic Resonance Imaging ,law.invention ,Diagnosis, Differential ,Intramedullary rod ,Intervertebral disk ,medicine.anatomical_structure ,law ,Cats ,Animals ,Medicine ,Extrusion ,business ,Disk space ,Intervertebral Disc Displacement ,Domestic shorthaired cat - Abstract
Intervertebral disk extrusion is rarely reported in the cat. In this case, the clinical, radiologic, and magnetic resonance imaging findings of an acute intramedullary intervertebral disk extrusion in a 5-year-old domestic shorthaired cat are described. Radiographically, there was mineralized disk material within the vertebral canal. On magnetic resonance images, the disk material was found to be within the spinal cord. A linear disk trail extending from the disk space into the spinal cord may be specific for intramedullary disk extrusion.
- Published
- 2004
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28. Magnetic resonance imaging findings of an intracranial medulloblastoma in a Polish Lowland Sheepdog
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Ken C. Smith, J. Fraser McConnell, and Simon R. Platt
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Male ,Cerebellum ,Pathology ,medicine.medical_specialty ,Fossa ,Diagnosis, Differential ,Dogs ,Cerebellar hemisphere ,medicine ,Animals ,Dog Diseases ,Cerebellar Neoplasms ,Medulloblastoma ,General Veterinary ,medicine.diagnostic_test ,biology ,business.industry ,Magnetic resonance imaging ,Anatomy ,biology.organism_classification ,medicine.disease ,Magnetic Resonance Imaging ,Pedigree ,medicine.anatomical_structure ,Polish Lowland Sheepdog ,business - Abstract
Medullobastoma is an uncommon caudal fossa tumor. The imaging features of medullobastoma in the dog are poorly described. In this report, the magnetic resonance (MR) appearance of a cerebellar medullobastoma in a dog is described. The MR features were similar to medulloblastomas in adult humans, with the tumor arising laterally and extending to the surface of the cerebellar hemisphere. Correct localization of medulloblastoma may be difficult and it should be considered as a differential for both extra- and intra-axial caudal fossa masses.
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- 2004
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29. IMAGING OF A SPINAL NEPHROBLASTOMA IN A DOG
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Laurent Garosi, Ken C. Smith, J. Fraser McConnell, and Ruth Dennis
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Gait Ataxia ,medicine.medical_specialty ,Wilms Tumor ,Thoracic Vertebrae ,law.invention ,Diagnosis, Differential ,Intramedullary rod ,Lesion ,Dogs ,law ,German Shepherd Dog ,medicine ,Animals ,Dog Diseases ,Spinal Cord Neoplasms ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Gait abnormality ,Thoracic vertebrae ,Spinal cord lesion ,Female ,Radiology ,medicine.symptom ,business ,Myelography - Abstract
An 8-month-old German Shepherd dog was presented for investigation of pelvic limb gait abnormality. Neurolocalization indicated a T3-L3 spinal cord lesion. The myelographic appearance was of an intramedullary lesion at T9/10, but upon subsequent magnetic resonance imaging it was determined that the mass was extramedullary. A diagnosis of nephroblastoma was made on histological examination. The imaging features of this rare tumor and the differentiation of intradural-extramedullary and intramedullary masses are discussed.
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- 2003
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30. Cervical intervertebral foraminal disc extrusion in dogs: clinical presentation, MRI characteristics and outcome after medical management
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Sebastien Behr, Peter M. Smith, Rita Gonçalves, Erika Bersan, Holger A. Volk, Fraser McConnell, Raquel Trevail, and S. De Decker
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Male ,medicine.medical_specialty ,Neurology ,Articular processes ,Physical examination ,Neurological examination ,Dogs ,medicine ,Animals ,Dog Diseases ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,General Medicine ,Spinal cord ,Magnetic Resonance Imaging ,Sagittal plane ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Lameness ,Cervical Vertebrae ,Female ,business ,Intervertebral Disc Displacement - Abstract
The aim of the present study was to retrospectively evaluate the clinical signs, MRI characteristics, interobserver agreement and outcome after medical treatment in dogs affected by cervical intervertebral foraminal disc extrusion (CIFDE). The medical records of three referral institutions were searched for dogs diagnosed with CIFDE between 2010 and 2012. Thirteen dogs were identified with CIFDE; affected dogs often had a normal neurological examination, with cervical hyperaesthesia and lameness as the most common clinical signs. On MRI, sagittal images showed no evidence of compression of the spinal cord; CIFDE could be identified only on transverse sections in all cases. An excellent interobserver agreement was found in the localisation of the affected intervertebral disc space, and a substantial agreement was found on the detection of CIFDE versus foraminal stenosis caused by overgrowing articular processes. All but two dogs recovered completely, and they were considered free of clinical signs without analgesia within a median of 7.5 weeks (range: 2–20) after medical management was started. The remaining two dogs were surgically treated followed by complete recovery. In view of our findings, the importance of a thorough MRI investigation in dogs presenting with cervical hyperaesthesia as the sole clinical sign should be highlighted.
- Published
- 2015
31. Focal cortical dysplasia resulting in seizures in an adult dog
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Fraser McConnell, Rita Gonçalves, Camilla Jayne Cooper, and Gemma Walmsley
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medicine.medical_specialty ,Seizure frequency ,Pathology ,Neurology ,General Veterinary ,business.industry ,Old English Sheepdog ,Cortical dysplasia ,Sulcus ,medicine.disease ,medicine.anatomical_structure ,Gyrus ,medicine ,Levetiracetam ,Differential diagnosis ,business ,medicine.drug - Abstract
A two-year-old, neutered male, old English sheepdog was presented for further investigation of generalised tonic-clonic seizures. MRI of the brain revealed cortical grey matter thickening, grey-white matter blurring and malformation of the prorean and precruciate gyrus and absence of the presylvian sulcus. These findings are consistent with congenital focal cortical dysplasia; although the histopathological findings have been previously described in dogs, the MRI findings have not yet been reported in the veterinary literature. Phenobarbitone was added at the time of diagnosis with levetiracetam being added after 12 months due to worsening seizure frequency. Cortical dysplasia, although uncommon, should be considered as a differential diagnosis in an adult dog with generalised seizures.
- Published
- 2015
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32. ANATOMICAL STUDY OF CRANIAL NERVE EMERGENCE AND SKULL FORAMINA IN THE HORSE USING MAGNETIC RESONANCE IMAGING AND COMPUTED TOMOGRAPHY
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Rita, Gonçalves, Fernando, Malalana, James Fraser, McConnell, and Thomas, Maddox
- Subjects
Hypoglossal Nerve ,Anatomy, Cross-Sectional ,Skull ,Cranial Nerves ,Brain ,Optic Nerve ,Trochlear Nerve ,Vagus Nerve ,Vestibulocochlear Nerve ,Magnetic Resonance Imaging ,Facial Nerve ,Accessory Nerve ,Abducens Nerve ,Oculomotor Nerve ,Cadaver ,Image Processing, Computer-Assisted ,Animals ,Horses ,Prospective Studies ,Trigeminal Nerve ,Tomography, X-Ray Computed ,Glossopharyngeal Nerve - Abstract
For accurate interpretation of magnetic resonance (MR) images of the equine brain, knowledge of the normal cross-sectional anatomy of the brain and associated structures (such as the cranial nerves) is essential. The purpose of this prospective cadaver study was to describe and compare MRI and computed tomography (CT) anatomy of cranial nerves' origins and associated skull foramina in a sample of five horses. All horses were presented for euthanasia for reasons unrelated to the head. Heads were collected posteuthanasia and T2-weighted MR images were obtained in the transverse, sagittal, and dorsal planes. Thin-slice MR sequences were also acquired using transverse 3D-CISS sequences that allowed mutliplanar reformatting. Transverse thin-slice CT images were acquired and multiplanar reformatting was used to create comparative images. Magnetic resonance imaging consistently allowed visualization of cranial nerves II, V, VII, VIII, and XII in all horses. The cranial nerves III, IV, and VI were identifiable as a group despite difficulties in identification of individual nerves. The group of cranial nerves IX, X, and XI were identified in 4/5 horses although the region where they exited the skull was identified in all cases. The course of nerves II and V could be followed on several slices and the main divisions of cranial nerve V could be distinguished in all cases. In conclusion, CT allowed clear visualization of the skull foramina and occasionally the nerves themselves, facilitating identification of the nerves for comparison with MRI images.
- Published
- 2014
33. Computed tomographic findings in 15 dogs with eosinophilic bronchopneumopathy
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Luis, Mesquita, Richard, Lam, Christopher R, Lamb, and J Fraser, McConnell
- Subjects
Male ,Bronchial Diseases ,Bronchiectasis ,Dogs ,Cough ,Eosinophilia ,Animals ,Multiple Pulmonary Nodules ,Female ,Dog Diseases ,Pulmonary Eosinophilia ,Tomography, X-Ray Computed ,Bronchoalveolar Lavage Fluid ,Lung ,Lymphatic Diseases ,Retrospective Studies - Abstract
Eosinophilic bronchopneumopathy is a disease characterized by the infiltration of the lung and bronchial mucosa by eosinophils. The aim of the present study was to describe the CT findings in a large series of dogs with confirmed diagnosis of eosinophilic bronchopneumopathy. Computed tomographic scans of 15 dogs with confirmed diagnosis of eosinophilic bronchopneumopathy were evaluated retrospectively by two boarded radiologists who reached a consensus. Abnormalities were identified in 14/15 (93%) dogs, including pulmonary parenchymal abnormalities in 14/15 (93%) dogs, bronchial wall thickening in 13 (87%) dogs, which was considered marked in eight (53%), plugging of the bronchial lumen by mucus/debris in 11 (73%) dogs, and bronchiectasis in nine (60%) dogs. Pulmonary nodules were identified in 5/15 (33%) dogs including one dog with a mass. All dogs with a nodular lung pattern had additional abnormalities. Lymphadenopathy was present in 10 dogs (67%). Lesions associated with eosinophilic bronchopneumopathy are variable and heterogeneous and encompass a wider variety of computed tomographic features than reported previously. Computed tomographic images were abnormal in the majority of affected dogs, hence CT is a useful modality to characterize the nature and distribution of thoracic lesions in dogs with eosinophilic bronchopneumopathy.
- Published
- 2014
34. Septic pericarditis and myocardial abscess in an English Springer spaniel
- Author
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Eduardo Fraga Manteiga, Gemma Fraga Veloso, Mary R Trehy, Joanna Dukes McEwan, Alistair Freeman, and J. Fraser McConnell
- Subjects
English Springer spaniel ,medicine.medical_specialty ,Myocarditis ,Physiology ,medicine.drug_class ,biology.animal_breed ,Antibiotics ,Pericardial effusion ,Pericarditis ,Lethargy ,Dogs ,medicine ,Endocarditis ,Animals ,Dog Diseases ,General Veterinary ,biology ,business.industry ,Arrhythmias, Cardiac ,bacterial infections and mycoses ,medicine.disease ,Abscess ,Surgery ,Anti-Bacterial Agents ,Female ,Foreign body ,business ,Anti-Arrhythmia Agents - Abstract
Septic pericarditis and myocardial abscess are rare conditions in dogs. They are usually caused by foreign bodies, penetrating wounds, systemic infections or extension of local infections such as endocarditis, pleuritis or pulmonary infections to the myocardial tissue. Here we report a septic pericardial effusion and myocardial abscess in a young English Springer spaniel presenting with a long history of pyrexia and lethargy. No cause could clearly be identified although a penetrating injury or dissolving foreign body was highly suspected. The patient was successfully treated with a surgical approach in combination with broad spectrum antibacterials resulting in resolution of clinical signs without recurrence of the infection.
- Published
- 2013
35. Radiographic and ultrasonographic changes of the patellar ligament following tibial tuberosity advancement in 25 dogs
- Author
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Martin A. Baker, R. Hattersley, N. D. Lorenz, Peter J. Cripps, Fraser McConnell, and Rob Pettitt
- Subjects
musculoskeletal diseases ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Radiography ,Osteotomy ,03 medical and health sciences ,0302 clinical medicine ,Tibial tuberosity advancement ,Dogs ,Patellar Ligament ,medicine ,Animals ,Clinical significance ,Dog Diseases ,Anterior Cruciate Ligament ,Prospective cohort study ,Ultrasonography ,030222 orthopedics ,General Veterinary ,Tibia ,business.industry ,Patellar ligament ,Ultrasound ,030229 sport sciences ,musculoskeletal system ,Surgery ,medicine.anatomical_structure ,Ligament ,Animal Science and Zoology ,Female ,business ,human activities - Abstract
SummaryIntroduction: Patellar ligament thickening is a recognized response following osteotomy of the proximal tibia as a treatment for cranial cruciate disease. In humans this is seen as a response to increased loading, but the reason for this thickening in dogs is unclear. A prospective study was undertaken to assess the degree and frequency of patellar ligament desmopathy in 25 consecutive cases undergoing tibial tuberosity advancement (TTA).Objectives: To determine the incidence of patellar ligament thickening following TTA.Methods: Consecutive cases undergoing TTA had ultrasonographic and radiographic measurements performed of the patellar ligament, at multiple positions on the ligament. This was performed at the time of surgery, and at six weeks and six months (ultrasound only) following surgery. The radiographic measurements were performed by two reviewers who were blinded to the timeframe of each image.Results: There was great variation in both the incidence and degree of thickening of the ligament. Fifty percent of the cases showed no changes in the thickness of the patellar ligament. A clinical pain response was not associated with patellar ligament thickening. No statistically significant variables which predicted the development of patellar ligament thickening were identified .Clinical significance: The presence of signs of patellar ligament thickening is of questionable clinical significance and is probably an incidental finding.
- Published
- 2012
36. Comparison between shoulder computed tomography and clinical findings in 89 dogs presented for thoracic limb lameness
- Author
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Thomas W, Maddox, Chris, May, Benjamin J, Keeley, and J Fraser, McConnell
- Subjects
Male ,Dogs ,Shoulder Joint ,Lameness, Animal ,Osteoarthritis ,Prevalence ,Animals ,Calcinosis ,Osteochondrosis ,Female ,Dog Diseases ,Tomography, X-Ray Computed ,Retrospective Studies - Abstract
Computed tomography (CT) is an established technique for detecting shoulder lesions in dogs, however the clinical significance of shoulder CT lesions often remains uncertain. The purposes of this retrospective study were to describe the prevalence of CT lesions in both shoulder joints for 89 dogs presenting with thoracic limb lameness and to compare CT lesions with clinical characteristics. For all included dogs, results of a full orthopedic examination, other diagnostic tests, and signalment data were available in medical records. Multilevel, multivariable logistic regression was used to test clinical significance of the most prevalent CT lesions and determine factors associated with their presence. Computed tomographic lesions were detected in one or both shoulder joints for 51/89 dogs (57.3%). Mineralization of one or more surrounding peri-articular soft-tissue structures was identified in 31.5% of dogs, with supraspinatus muscle/tendon mineralization being the most frequently identified (24.7%). The prevalence of humeral head osteochondrosis was 9 and 21.3% of dogs had shoulder osteoarthritis. Border collies (odds ratio [OR] 9.3; 95% CI 1.39-62.1, P = 0.02) and dogs with shoulder pain (OR 4.3; 95% CI 1.08-17.1, P = 0.04) had increased risk of osteochondrosis lesions. Border collies (OR 8.4; 95% CI 1.27-55.6; P = 0.03) and older animals (OR 1.04; 95% CI 1.02-1.1, P0.001) had increased risk of osteoarthritis lesions. Female entire dogs had an increased risk of supraspinatus mineralization lesions (OR 6.8; 95% CI 1.55-29.5, P = 0.01). Findings indicated that shoulder CT lesions are common in dogs with thoracic limb lameness, and that some CT lesions are not associated with shoulder pain.
- Published
- 2012
37. Unique topographic distribution of greyhound nonsuppurative meningoencephalitis
- Author
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Eloisa, Terzo, J Fraser, McConnell, Robert E, Shiel, Hester, McAllister, Sebastien, Behr, Simon L, Priestnall, Ken C, Smith, Catherine M, Nolan, and John J, Callanan
- Subjects
Male ,Dogs ,Meningoencephalitis ,Animals ,Brain ,Female ,Dog Diseases ,Magnetic Resonance Imaging - Abstract
Greyhound nonsuppurative meningoencephalitis is an idiopathic breed-associated fatal meningoencephalitis with lesions usually occurring within the rostral cerebrum. This disorder can only be confirmed by postmortem examination, with a diagnosis based upon the unique topography of inflammatory lesions. Our purpose was to describe the magnetic resonance (MR) imaging features of this disease. Four Greyhounds with confirmed Greyhound nonsuppurative meningoencephalitis were evaluated by MR imaging. Lesions predominantly affected the olfactory lobes and bulbs, frontal, and frontotemporal cortical gray matter, and caudate nuclei bilaterally. Fluid attenuation inversion recovery (FLAIR) and T2 weighted spin-echo (T2W) sequences were most useful to assess the nature, severity, extension, and topographic pattern of lesions. Lesions were predominantly T2-hyperintense and T1-isointense with minimal or absent contrast enhancement.
- Published
- 2012
38. Clinical, morphologic, and morphometric features of cranial thoracic spinal stenosis in large and giant breed dogs
- Author
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Philippa, Johnson, Luisa, De Risio, Andrew, Sparkes, Fraser, McConnell, and Andrew, Holloway
- Subjects
Male ,Radiography ,Dogs ,Spinal Stenosis ,Animals ,Body Size ,Female ,Dog Diseases ,Magnetic Resonance Imaging ,Spinal Cord Compression ,Thoracic Vertebrae - Abstract
The clinical, morphologic, and morphometric features of cranial thoracic spinal stenosis were investigated in large and giant breed dogs. Seventy-nine magnetic resonance imaging studies of the cranial thoracic spine were assessed. Twenty-six were retrieved retrospectively and 53 were acquired prospectively using the same inclusion criteria. Images were evaluated using a modified compression scale as: no osseous stenosis (grade 0), osseous stenosis without spinal cord compression (grade 1), and osseous stenosis with spinal cord compression (grade 2). Morphometric analysis was performed and compared to the subjective grading system. Grades 1 and 2 cranial thoracic spinal stenosis were identified on 24 imaging studies in 23 dogs. Sixteen of 23 dogs had a conformation typified by Molosser breeds and 21/23 were male. The most common sites of stenosis were T2-3 and T3-4. The articular process joints were enlarged with abnormal oblique orientation. Stenosis was dorsolateral, lateralized, or dorsoventral. Concurrent osseous cervical spondylomyelopathy was recognized in six dogs and other neurologic disease in five dogs. Cranial thoracic spinal stenosis was the only finding in 12 dogs. In 9 of these 12 dogs (all grade 2) neurolocalization was to the T3-L3 spinal segment. The median age of these dogs was 9.5 months. In the remaining three dogs neurologic signs were not present. Stenosis ratios were of limited benefit in detecting stenotic sites. Grade 2 cranial thoracic spinal stenosis causing direct spinal cord compression may lead to neurologic signs, however milder stenosis (grade 1) is likely to be subclinical or incidental.
- Published
- 2012
39. Imaging diagnosis--Ventriculo-peritoneal shunt associated infection in a dog
- Author
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Simon R, Platt, J Fraser, McConnell, and Lara, Matiasek
- Subjects
Dogs ,Animals ,Encephalitis ,Dog Diseases ,Staphylococcal Infections ,Magnetic Resonance Imaging ,Ventriculoperitoneal Shunt ,Hydrocephalus - Abstract
Ventriculo-peritoneal shunting is a surgical treatment for hydrocephalus. Complications of this procedure are not well described in dogs. The most common complication in humans is infection, which can be fatal if not diagnosed and treated quickly. We describe the magnetic resonance (MR) imaging characteristics of a shunt-associated cerebral infection in a dog. The MR features of the infection included hyperintensity of the lining of the ventricular system visible on a T2-weighted FLAIR sequence and marked linear contrast enhancement of the ependymal layer on T1-weighted sequences, similar to that described in people.
- Published
- 2011
40. Frontal sinus depth at four landmarks in breeds of dog typically affected by sinonasal aspergillosis
- Author
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Martin A. Baker, Rachel Burrow, Peter J. Cripps, D. McCarroll, P. Darby, and Fraser McConnell
- Subjects
Male ,endocrine system ,Breeding ,Aspergillosis ,Teaching hospital ,Dogs ,Small animal ,Nose Diseases ,medicine ,Animals ,Dog Diseases ,Sinus (anatomy) ,Frontal sinus ,General Veterinary ,business.industry ,Significant difference ,General Medicine ,Anatomy ,medicine.disease ,humanities ,medicine.anatomical_structure ,Case-Control Studies ,Frontal Sinus ,Female ,business ,Tomography, X-Ray Computed - Abstract
The objective of this study was to assess whether the frontal sinuses in dogs with aspergillosis and of breeds typically affected by this condition were deeper at a more caudal location. CT scans of the head performed at the Small Animal Teaching Hospital, University of Liverpool, between April 2007 and March 2009 for dogs diagnosed with aspergillosis (group 1) and unaffected dogs of similar breeds (group 2) were selected for study. Sinus depth was measured at four standardised locations from reconstructed images of these CT scans. Data were compared for differences in sinus depth between groups and between landmarks. No significant difference was found between measurements within individual dogs or for each of the various landmarks between groups. Difference in depth of the sinuses between landmarks was significant (P
- Published
- 2011
41. Trephination of the frontal sinuses and instillation of clotrimazole cream: a computed tomographic study in canine cadavers
- Author
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Rachel, Burrow, Martin, Baker, Lindsay, White, and James Fraser, McConnell
- Subjects
Male ,Antifungal Agents ,Dogs ,Frontal Sinusitis ,Animals ,Aspergillosis ,Frontal Sinus ,Female ,Dog Diseases ,Clotrimazole ,Tomography, X-Ray Computed ,Administration, Intranasal - Abstract
To use computed tomography (CT) to assess the distribution of surgically administered clotrimazole cream and associated filling of the frontal sinuses and caudal aspect of the nasal cavities in canine cadavers.Observational study.Small (n = 1) and medium-large (n = 11) breed canine cadavers.CT scans of 12 cadaveric canine heads were used to confirm absence of sinonasal disease. Then after creating an opening into the left and right frontal sinuses with a 3.2 mm Steinmann pin at standardized landmarks, clotrimazole cream (20 g) was instilled into each side. Postoperative CT scans of the heads was used to assess the distribution and degree of filling of the sinonasal cavities with clotrimazole cream, and to identify any damage to local structures.Filling was excellent in 22 sinuses, very poor in 2, and excellent in all caudal nasal cavities. Two cadavers had damage: unilateral penetration of the cranium (2) and unilateral penetration of the lateral sinus wall (1).Excellent filling of most of the frontal sinuses and caudal nasal cavity of cadavers with clotrimazole cream is achieved when administered by this technique. Damage to local structures may occur intraoperatively using this technique.
- Published
- 2011
42. Magnetic resonance imaging features of discospondylitis in dogs
- Author
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Inés, Carrera, Martin, Sullivan, Fraser, McConnell, and Rita, Gonçalves
- Subjects
Discitis ,Dogs ,Lumbar Vertebrae ,Lumbosacral Region ,Animals ,Dog Diseases ,Magnetic Resonance Imaging ,Thoracic Vertebrae - Abstract
The diagnosis of discospondylitis is based mainly on diagnostic imaging and laboratory results. Herein, we describe the magnetic resonance imaging (MRI) findings in 13 dogs with confirmed discospondylitis. In total there were 17 sites of discospondylitis. Eleven (81.1%) of the dogs had spinal pain for3 weeks and a variable degree of neurologic signs. Two dogs had spinal pain and ataxia for 4 days. Radiographs were available in nine of the dogs. In MR images there was always involvement of two adjacent vertebral endplates and the associated disk. The involved endplates and adjacent marrow were T1-hypointense with hyperintensity in short tau inversion recovery (STIR) images in all dogs, and all dogs also had contrast enhancement of endplates and paravertebral tissues. The intervertebral disks were hyperintense in T2W and STIR images and characterized by contrast enhancement in 15 sites (88.2%). Endplate erosion was present in 15 sites (88.2%) and was associated with T2-hypointense bone marrow adjacent to it. In two sites (11.8%) endplate erosion was not MR images or radiographically. The vertebral bone marrow in these sites was T2-hyperintense. Epidural extension was conspicuous in postcontrast images at 15 sites (88.2%). Spinal cord compression was present at 15 sites (88.2%), and all affected dogs had neurologic signs. Subluxation was present in two sites (11.8%). MRI shows characteristic features of discospondylitis, and it allows the recognition of the exact location and extension (to the epidural space and paravertebral soft tissues) of the infection. Furthermore, MRI increases lesion conspicuity in early discospondylitis that may not be visualized by radiography.
- Published
- 2011
43. Magnetic resonance imaging features of paraspinal infection in the dog and cat
- Author
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Ruth Dennis, Andrew Holloway, Fraser McConnell, and M. E. Herrtage
- Subjects
medicine.medical_specialty ,Iliopsoas Muscle ,Thoracolumbar fascia ,Lumbar vertebrae ,Cat Diseases ,Thoracic Vertebrae ,Dogs ,Muscular Diseases ,Medicine ,Animals ,Spinal canal ,Dog Diseases ,Abscess ,Muscle, Skeletal ,Lumbar Vertebrae ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Anatomy ,Bacterial Infections ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Thoracic vertebrae ,Cats ,Radiology ,Iliopsoas ,business ,Spinal Canal - Abstract
The magnetic resonance (MR) imaging findings in 22 dogs and two cats with confirmed paraspinal infection of the thoracolumbar spine were characterized. These findings included extensive T2-hyperintense areas (24/24), abscessation (20/24), mild inherent T1-hyperintensity of muscle and abscesses (18/24), and postcontrast enhancement (24/24). Changes involved the vertebral canal in four patients. The longus coli muscles were affected in one cat. Thoracolumbar changes in the remaining 23 patients involved the iliopsoas and epaxial muscles in 23/23 and 19/23 patients, respectively. Iliopsoas muscle abscessation was unilateral in 12/23, and bilateral in 6/24 patients. Abscessation involved both epaxial and iliopsoas muscles in 2/23 patients and the epaxial muscles alone in one patient. A contrast-enhancing sinus tract within the deep thoracolumbar fascia was present in 10/23 patients. Lumbar vertebrae periosteal reactions were identified in 19/23 patients on MR images compared with 15/17 patients with radiography. A focal area of signal void suspected to represent foreign material was seen in 5/23 patients but foreign material was actually found in only two of these five. There was no recurrence of clinical signs following MR imaging and revision surgery. MR imaging permits the severity and extent of changes associated with paraspinal infection to be characterized and allows the location, number and any communication of sinus tracts to be documented.
- Published
- 2009
44. Abdominal radiography
- Author
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J. Fraser McConnell
- Published
- 2009
- Full Text
- View/download PDF
45. Association of clinical and magnetic resonance imaging findings with outcome in dogs suspected to have ischemic myelopathy: 50 cases (2000-2006)
- Author
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Simon R. Platt, Ruth Dennis, Luisa De Risio, Vicki J. Adams, and Fraser McConnell
- Subjects
Male ,medicine.medical_specialty ,Neurologic Signs ,Severity of Illness Index ,Lesion ,Dogs ,Predictive Value of Tests ,Ischemic myelopathy ,Severity of illness ,Medicine ,Animals ,Dog Diseases ,Retrospective Studies ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Spinal Cord Ischemia ,Medical record ,Retrospective cohort study ,Magnetic resonance imaging ,Prognosis ,Magnetic Resonance Imaging ,Predictive value of tests ,Female ,Radiology ,medicine.symptom ,business - Abstract
Objective—To determine whether clinical signs or magnetic resonance imaging findings were associated with outcome in dogs with presumptive ischemic myelopathy. Design—Retrospective case series. Animals—50 dogs. Procedures—Medical records and magnetic resonance images were reviewed. A neurologic score from 1 (normal) to 5 (most severe degree of dysfunction) was assigned on the basis of neurologic signs at the time of initial examination. Follow-up information was obtained from the medical records and by means of a telephone questionnaire completed by owners and referring veterinarians. Results—Median neurologic score at the time of initial examination was 3 (range, 2 to 5). Median follow-up time was 584 days (range, 4 to 2,090 days). Neurologic score at the time of initial examination and extent of the lesion seen on magnetic resonance images (quantified as the lesion length-to-vertebral length ratio and as the percentage cross-sectional area of the lesion) were significantly associated with outcome. Sensitivity of using a lesion length-to-vertebral length ratio > 2.0 or a percentage cross-sectional area of the lesion ≥ 67% to predict an unsuccessful outcome was 100%. Conclusions and Clinical Relevance—Results suggested that severity of neurologic signs at the time of initial examination and extent of the lesions seen on magnetic resonance images were associated with outcome in dogs with ischemic myelopathy.
- Published
- 2008
46. The lung parenchyma
- Author
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Gabriela S. Seiler, Robert T. O'Brien, Fraser McConnell, Wilfried Maï, Allison L. Zwingenberger, Peter Scrivani, Yael Porat-Mosenco, Emma Tobin, and Tobias Schwarz
- Subjects
CATS ,business.industry ,Parenchyma ,Medicine ,Anatomy ,respiratory system ,business ,Radiographic anatomy ,respiratory tract diseases - Abstract
Dogs and cats have two lungs, which are not symmetrical in terms of size and lobation. The lobar anatomy is based on the bronchial division. The chapter is divided into the following sections: Radiographic anatomy; Interpretive principles and Diseases.
- Published
- 2008
- Full Text
- View/download PDF
47. Basics of thoracic magnetic resonance imaging
- Author
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Fraser McConnell
- Subjects
Soft tissue contrast ,medicine.diagnostic_test ,Thoracic disease ,Presurgical planning ,business.industry ,medicine ,Magnetic resonance imaging ,business ,Nuclear medicine - Abstract
The principal indication for magnetic resonance imaging (MRI) of thoracic disease in small animals is the evaluation of thoracic masses. MRI is of particular value for presurgical planning due to the excellent soft tissue contrast it provides and its ability to obtain images in any plane. This section looks at Indications; Restraint and patient preparation; Technique.
- Published
- 2008
- Full Text
- View/download PDF
48. The potential role of MRI in veterinary clinical cardiology
- Author
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Fraser McConnell, Stephen Gilbert, Joanna Dukes-McEwan, Arun V. Holden, and Mohan U. Sivananthan
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Clinical cardiology ,Veterinary Medicine ,Veterinary medicine ,Diagnostic methods ,General Veterinary ,medicine.diagnostic_test ,Ventricular function ,Heart Diseases ,business.industry ,Heart Valve Diseases ,Hemodynamics ,Magnetic resonance imaging ,Cat Diseases ,Magnetic Resonance Imaging ,Myocardial Contraction ,Dogs ,Small animal ,Computer software ,medicine ,Cats ,Animals ,Humans ,Animal Science and Zoology ,Dog Diseases ,business - Abstract
Over the last decade, magnetic resonance imaging (MRI) has become established as a useful referral diagnostic method in veterinary medicine that is widely used in small animal brain and spinal diseases, aural, nasal and orbital disorders, planning soft tissue surgery, oncology and small animal and equine orthopaedics. The use of MRI in these disciplines has grown due to its unparalleled capability to image soft tissue structures. This has been exploited in human cardiology where, despite the inherent difficulties in imaging a moving, contractile structure, cardiac MRI (CMRI) has become the optimal technique for the morphological assessment and quantification of ventricular function. Both CMRI hardware and software systems have developed rapidly in the last 10 years but although several preliminary veterinary CMRI studies have been reported, the technique's growth has been limited and is currently used primarily in clinical research. A review of published studies is presented with a description of CMRI technology and the potential of CMRI is discussed along with some of the reasons for its limited usage.
- Published
- 2007
49. Retrobulbar teratoma causing exophthalmos in a cat
- Author
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Jonathan D. Wray, A. S. Blunden, Ruth Dennis, Ross T. Doust, and Fraser McConnell
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medicine.medical_specialty ,Extragonadal ,Exophthalmos ,Biology ,Cat Diseases ,Complete resection ,Lesion ,Diagnosis, Differential ,medicine ,Soft tissue mass ,Animals ,Small Animals ,medicine.diagnostic_test ,Eye Neoplasms ,Teratoma ,Magnetic resonance imaging ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Treatment Outcome ,Cats ,Surgical excision ,Female ,medicine.symptom - Abstract
A 3-year female-neutered domestic shorthair cat presenting with exophthalmos and an ipsilateral subzygomatic soft tissue mass lesion is described. Magnetic resonance imaging of the mass was performed followed by complete surgical excision. The mass was determined to be a retrobulbar teratoma and complete resection was curative. Teratomas are rare germ-cell tumours that uncommonly form in extragonadal sites. A retrobulbar location has not been previously reported in the cat and should be considered a rare cause of exophthalmos in this species.
- Published
- 2007
50. Magnetic resonance imaging characteristics of ascending hemorrhagic myelomalacia in a dog
- Author
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Simon R. Platt, Mark Bestbier, and J. Fraser McConnell
- Subjects
Paraplegia ,medicine.medical_specialty ,General Veterinary ,medicine.diagnostic_test ,business.industry ,Myelitis ,Magnetic resonance imaging ,medicine.disease ,Magnetic Resonance Imaging ,Hyperintensity ,Lesion ,Dogs ,medicine ,Paralysis ,Animals ,Neutered female ,Female ,Radiology ,Dog Diseases ,medicine.symptom ,business ,Myelomalacia - Abstract
A 4-year-old neutered female terrier-cross was evaluated for an acute onset of paraplegia. Utilizing magnetic resonance (MR) imaging, the cause of the neurologic deficits was determined to be a lumbar intervertebral disc extrusion. The MR study additionally demonstrated parenchymal hyperintensity on T2-weighted images and similarly located diffuse hypointensity on gradient echo images, cranial and caudal to the compressive extradural lesion. Hemorrhagic myelomalacia was suspected based on these MR characteristics, which was subsequently confirmed surgically and histopathologically.
- Published
- 2006
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