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19 results on '"Haddad, Francois"'

1. Additional file 16 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 16

Published
2022
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2. Additional file 1 of Multi-dimensional characterization of prediabetes in the Project Baseline Health Study

Author

Chatterjee, Ranee, Kwee, Lydia Coulter, Pagidipati, Neha, Koweek, Lynne H., Mettu, Priyatham S., Haddad, Francois, Maron, David J., Rodriguez, Fatima, Mega, Jessica L., Hernandez, Adrian, Mahaffey, Kenneth, Palaniappan, Latha, and Shah, Svati H.

Abstract

Additional file 1: Table S1. All clinical variables included in the calculation of PCA factors. Table S2. PCA factors significantly associated overall with diabetes groups, with no differences between DM and noDM. Table S3a. Individual variables with high loadings in PCA factors associated with diabetes categories in the multivariable models. Table S3b. A priori individual variables associated with diabetes categories in the multivariable models. Table S4. Individual variables with high loadings in PCA factors associated with progression to diabetes and reversion to no diabetes.

Published
2022
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3. Additional file 17 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 17

Published
2022
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4. Additional file 13 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 13

Published
2022
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5. Additional file 8 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 8

Published
2022
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6. Additional file 5 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 5

Published
2022
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7. Additional file 2 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 2

Published
2022
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8. Additional file 11 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 11

Published
2022
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9. Additional file 15 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 15

Published
2022
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10. Additional file 12 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 12

Published
2022
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11. Additional file 9 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 9

Published
2022
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12. Additional file 14 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 14

Published
2022
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13. Additional file 4 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 4

Published
2022
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14. Additional file 7 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 7

Published
2022
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15. Additional file 3 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 3

Published
2022
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16. Additional file 10 of 4D flow cardiovascular magnetic resonance recovery profiles following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Author

Dong, Melody L., Azarine, Arshid, Haddad, Francois, Amsallem, Myriam, Kim, Young-Wouk, Yang, Weiguang, Fadel, Elie, Aubrege, Laure, Loecher, Michael, Ennis, Daniel, Pavec, Jérôme Le, Vignon-Clementel, Irene, Feinstein, Jeffrey A., Mercier, Olaf, and Marsden, Alison L.

Abstract

Supplementary Material 10

Published
2022
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17. Pulmonary Hypertension in the Context of Heart Failure With Preserved Ejection Fraction

Author

Inampudi, Chakradhari, Silverman, Daniel, Simon, Marc A, Leary, Peter J, Sharma, Kavita, Houston, Brian A, Vachiéry, Jean-Luc, Haddad, Francois, and Tedford, Ryan J

Subjects
Heart Failure, heart failure with preserved ejection fraction, diastolic heart failure, Clinical Sciences, Respiratory System, Stroke Volume, Pulmonary, right ventricle, Cardiovascular, left heart disease, Heart Disease, Clinical Research, Hypertension, pulmonary hypertension, Humans, Vascular Resistance, KEY WORDS, Lung
Abstract

Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure and frequently is associated with pulmonary hypertension (PH). HFpEF associated with PH may be difficult to distinguish from precapillary forms of PH, although this distinction is crucial because therapeutic pathways are divergent for the two conditions. A comprehensive and systematic approach using history, clinical examination, and noninvasive and invasive evaluation with and without provocative testing may be necessary for accurate diagnosis and phenotyping. After diagnosis, HFpEF associated with PH can be subdivided into isolated postcapillary pulmonary hypertension (IpcPH) and combined postcapillary and precapillary pulmonary hypertension (CpcPH) based on the presence or absence of elevated pulmonary vascular resistance. CpcPH portends a worse prognosis than IpcPH. Despite its association with reduced functional capacity and quality of life, heart failure hospitalizations, and higher mortality, therapeutic options focused on PH for HFpEF associated with PH remain limited. In this review, we aim to provide an updated overview on clinical definitions and hemodynamically characterized phenotypes of PH, pathophysiologic features, therapeutic strategies, and ongoing challenges in this patient population.

Published
2021

18. Cumulative Lifetime Burden of Cardiovascular Disease From Early Exposure to Air Pollution

Author

Kim, Juyong Brian, Prunicki, Mary, Haddad, Francois, Dant, Christopher, Sampath, Vanitha, Patel, Rushali, Smith, Eric, Akdis, Cezmi, Balmes, John, Snyder, Michael P, Wu, Joseph C, Nadeau, Kari C, and University of Zurich

Subjects
Adult, Male, Aging, Time Factors, Adolescent, cardiovascular abnormalities, 610 Medicine & health, Comorbidity, Cardiorespiratory Medicine and Haematology, Global Health, Cardiovascular, Risk Assessment, 2705 Cardiology and Cardiovascular Medicine, environmental, Young Adult, Child Development, Sustainable Cities and Communities, 10183 Swiss Institute of Allergy and Asthma Research, Risk Factors, 2.3 Psychological, cardiovascular disease, Air Pollution, 80 and over, Humans, 2.2 Factors relating to the physical environment, Climate-Related Exposures and Conditions, air pollutants, Aetiology, Child, Preschool, Aged, Prevention, Age Factors, Infant, Environmental Exposure, Adolescent Development, Middle Aged, Newborn, Heart Disease, Good Health and Well Being, Cardiovascular Diseases, Female, epithelial barrier, social and economic factors, Cardiology and Cardiovascular Medicine
Abstract

The disease burden associated with air pollution continues to grow. The World Health Organization (WHO) estimates ≈7million people worldwide die yearly from exposure to polluted air, half of which-3.3million-are attributable to cardiovascular disease (CVD), greater than from major modifiable CVD risks including smoking, hypertension, hyperlipidemia, and diabetes mellitus. This serious and growing health threat is attributed to increasing urbanization of the world's populations with consequent exposure to polluted air. Especially vulnerable are the elderly, patients with pre-existing CVD, and children. The cumulative lifetime burden in children is particularly of concern because their rapidly developing cardiopulmonary systems are more susceptible to damage and they spend more time outdoors and therefore inhale more pollutants. World Health Organization estimates that 93% of the world's children aged

Published
2020

19. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement

Author

Lahm, Tim, Douglas, Ivor S, Archer, Stephen L, Bogaard, Harm J, Chesler, Naomi C, Haddad, Francois, Hemnes, Anna R, Kawut, Steven M, Kline, Jeffrey A, Kolb, Todd M, Mathai, Stephen C, Mercier, Olaf, Michelakis, Evangelos D, Naeije, Robert, Tuder, Rubin M, Ventetuolo, Corey E, Vieillard-Baron, Antoine, Voelkel, Norbert F, Vonk-Noordegraaf, Anton, Hassoun, Paul M, and American Thoracic Society Assembly on Pulmonary Circulation

Subjects
pulmonary embolism, Research, Respiratory System, acute respiratory distress syndrome, right ventricle, Cardiovascular, Medical and Health Sciences, United States, Right, Heart Disease, Rare Diseases, pulmonary circulation, Medical, American Thoracic Society Assembly on Pulmonary Circulation, pulmonary hypertension, Ventricular Dysfunction, Animals, Humans, Ventricular Function, Societies, Lung
Abstract

BackgroundRight ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- and long-term outcomes. Although remarkable progress has been made in the understanding of RV function and failure since the meeting of the NIH Working Group on Cellular and Molecular Mechanisms of Right Heart Failure in 2005, significant gaps remain at many levels in the understanding of cellular and molecular mechanisms of RV responses to pressure and volume overload, in the validation of diagnostic modalities, and in the development of evidence-based therapies.MethodsA multidisciplinary working group of 20 international experts from the American Thoracic Society Assemblies on Pulmonary Circulation and Critical Care, as well as external content experts, reviewed the literature, identified important knowledge gaps, and provided recommendations.ResultsThis document reviews the knowledge in the field of RV failure, identifies and prioritizes the most pertinent research gaps, and provides a prioritized pathway for addressing these preclinical and clinical questions. The group identified knowledge gaps and research opportunities in three major topic areas: 1) optimizing the methodology to assess RV function in acute and chronic conditions in preclinical models, human studies, and clinical trials; 2) analyzing advanced RV hemodynamic parameters at rest and in response to exercise; and 3) deciphering the underlying molecular and pathogenic mechanisms of RV function and failure in diverse pulmonary hypertension syndromes.ConclusionsThis statement provides a roadmap to further advance the state of knowledge, with the ultimate goal of developing RV-targeted therapies for patients with RV failure of any etiology.

Published
2018

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