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1. HOW DOES THE SILENCING OF THE INFLAMMATION MEDIATOR GENE: FAT10, EXTEND LIFESPAN IN MICE?

Author

Gulez B, Henegariu O, Zhang J, Garcia Milian R, Arjona C, Seay M, and Canaan A

Subjects
Health (social science), business.industry, Inflammation, Biology, Health Professions (miscellaneous), Cell biology, Abstracts, Text mining, Mediator, medicine, Gene silencing, medicine.symptom, Life-span and Life-course Studies, business, Gene
Abstract

FAT10 knockout mice display 50% reduction in total body fat and 20% increase in median and maximal lifespan, in both sexes. It is still unclear how FAT10 silencing affects aging and metabolism. Our current studies provide novel mechanistic insights for the role of this inflammation related gene - FAT10 in aging and metabolism.

Published
2017

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