1. SMJERNICE ZA PREVENCIJU, PREPOZNAVANJE I LIJEČENJE NEDOSTATKA VITAMINA D U ODRASLIH
- Author
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Vranešić Bender, D., Giljević, Z., Kušec, V., Nadica Laktašić Žerjavić, Bošnjak Pašic, M., Vrdoljak, E., Lkinas Kelećić Dina, Reiner, Ž, Anić, B., and Krznarić, Ž
- Subjects
Adult ,Croatia ,Risk Factors ,Evidence-Based Practice ,Preventive Health Services ,Humans ,Vitamin D defi ciency – etiology, diagnosis, complications, drug therapy, prevention and control ,Vitamin D – blood, standards, therapeutic use, administration and dosage ,Practice guidelines as topic ,Nedostatak vitamina D – etiologija, dijagnoza, komplikacije, farmakoterapija, prevencija ,Vitamin D – u krvi, standardi, terapijska primjena ,Smjernice ,Hrvatska ,Vitamin D ,Vitamin D Deficiency ,Risk Assessment - Abstract
Procjenjuje se da više od milijarde ljudi diljem svijeta ima niske koncentracije vitamina D zbog čega se s pravom govori o „pandemiji“ hipovitaminoze D te se razmatraju teške posljedice za javno zdravstvo. Geografski položaj Republike Hrvatske, posebice kontinentalnog dijela zemlje, čimbenik je rizika od pojave nedostatka vitamina D u populaciji. Cilj je ovih smjernica pružiti kliničarima jasan i jednostavan alat za prevenciju, prepoznavanje i liječenje nedostatka vitamina D u zdravoj populaciji i u različitih skupina bolesnika. Ove su smjernice nastale suradnjom kliničara različitih disciplina koji se bave brojnim aspektima skrbi o bolesnicima u riziku od razvoja nedostatka vitamina D. Utemeljene su na dokazima, prema sustavu GRADE (engl. Grading of Recommendations, Assessment, Development and Evaluation) koji uz snagu dokaza opisuje i razinu preporuke. Temeljni zaključci ovih smjernica odnose se na preporučenu populacijsku koncentraciju vitamina D u krvi koja iznosi 75 – 125 nmol/L te na definiranje preventivnih i terapijskih doza vitamina D za postizanje njegovih preporučenih koncentracija, It is estimated that over one billion of people around the globe have low serum values of vitamin D, therefore, we can consider vitamin D deficiency as a pandemic and public health problem. Geographic position of Croatia, especially the continental part of the country, is a risk factor for the development of deficiency of vitamin D in the population. The aim of these guidelines is to provide the clinicians with easy and comprehensive tool for prevention, detection and therapy of vitamin D deficienncy in healthy population and various groups of patients. They were made as a result of collaboration of clinicians of different backgrounds who are dealing with patients at risk of vitamin D deficiency. These guidelines are evidence-based, according to GRADE-system (Grading of Recommendations, Assessment, Development and Evaluation), which describes the level of evidence and strength of recommendation. The main conclusions address the recommended serum vitamin D values in the population which should be between 75 and 125 nmol/L and defining recommended preventive and therapeutic dosages of vitamin D in order to reach the adequate levels of serum vitamin D.