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Background: Saliva is the 1st defense fluid with sialic acid is a significant salivary biomarker. It is an acidicsugar with a nine-carbon backbone, able to mediate a wide variety of patho- physiological processes. thestudy aims at estimate salivary sialic acid in Iraqi children sample and also find out their association withoral health status.Method: Unstimulated salivary samples were collected from 100 healthy child, aged 6-13 years for5-minutes, between 9:00 - 11:00 A.M. gingival index(GI) and Plaque index were measured . According toWHO criteria,the dentition status was examined by dmfs, dmft,DMFS and DMFT. Also, flow rate and thelevel of salivary sialic acid were estimated.Results: In the present study,a positive correlation coefficient is recorded between the salivary flow rate andage and statistically reach the level of significance. Sialic acid concentration increased with age, but did notreach the level of significant.A male gender showed increase salivary sialic acid level by 0.2 U/L compared to female, but fail to reachthe significanceGI and DMFs showed a positive association with sialic acid level (R=0.036,R= 0.0053),but it’s not reachthe significant. While sialic acid level observed that a significant weak inverse liner correlation with othervariables like DMFS and PI,(R=- 0.082,R=-0.066)The outcomes were exposed to t-test and Pearson’s correlation coefficient, Plaque index, GI, flow rate andthe dental caries status were significantly positive correlated with the sialic acid levels in saliva.Conclusion: The salivary factors evaluated in this study may prove to be useful measures for gingivalinflammation in children and allow pediatric dentists to target preventive measures appropriately