1. Temporal Trends and Contemporary Outcomes After Transcatheter Aortic Valve Replacement With Evolut PRO/PRO+ Self-Expanding Valves: Insights From the NEOPRO/NEOPRO-2 Registries
- Author
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Scotti, Andrea, Baggio, Sara, Pagnesi, Matteo, Barbanti, Marco, Adamo, Marianna, Eitan, Amnon, Estévez-Loureiro, Rodrigo, Veulemans, Verena, Toggweiler, Stefan, Mylotte, Darren, De Marco, Federico, Giannini, Francesco, Ferlini, Marco, Naber, Christoph K, Buono, Andrea, Schofer, Joachim, Rottbauer, Wolfgang, Van Mieghem, Nicolas M, Khogali, Saib, Taramasso, Maurizio, Pilgrim, Thomas, Sinning, Jan-Malte, Zweiker, David, Montorfano, Matteo, Van der Heyden, Jan A S, Brugaletta, Salvatore, Ielasi, Alfonso, Hamm, Christian W, Vanhaverbeke, Maarten, Costa, Giuliano, Massussi, Mauro, Alarcón, Robert, Zeus, Tobias, Lunardi, Mattia, Testa, Luca, Di Ienno, Luca, Lanzillo, Giuseppe, Wolf, Alexander, Maffeo, Diego, Ziviello, Francesca, Saccocci, Matteo, Windecker, Stephan, Sedaghat, Alexander, Schmidt, Albrecht, Brouwer, Jorn, Regueiro, Ander, Reimers, Bernhard, Kim, Won-Keun, Sondergaard, Lars, Colombo, Antonio, Mangieri, Antonio, and Latib, Azeem
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610 Medizin und Gesundheit - Abstract
BACKGROUND In recent years, transcatheter aortic valve replacement (TAVR) techniques and technology have continuously improved. Data regarding the impact of these advancements on outcomes in large real-world settings are still limited. The aim of this study was to investigate temporal trends and assess contemporary outcomes after TAVR with Evolut PRO/PRO+ supra-annular self-expanding valves. METHODS This study included patients enrolled in the multicenter NEOPRO (A Multicenter Comparison of Acurate NEO Versus Evolut PRO Transcatheter Heart Valves) and NEOPRO-2 (A Multicenter Comparison of ACURATE NEO2 Versus Evolut PRO/PRO+ Transcatheter Heart Valves 2) registries who underwent transfemoral TAVR with Evolut PRO/PRO+. Procedural dates (August 2017 through November 2021) were stratified in quartiles (Q) and used to investigate temporal trends in TAVR outcomes. Predischarge, 30-day Valve Academic Research Consortium-3 defined, and 1-year outcomes were evaluated. RESULTS In total, 1616 patients from 28 centers were included. Over time, patients had lower Society of Thoracic Surgeon-Predicted Risk of Mortality score (Q1-4, 4.1% [2.8-6.3%], 3.7% [2.6-5.3%], 3.3% [2.4-4.9%], 2.9% [2.2-4.3%]; P
- Published
- 2023
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