1. Acute vertebral collapse due to osteoporosis or malignancy: appearance on unenhanced and gadolinium-enhanced MR images
- Author
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S Chevret, X Chapaux, Naouri Jf, Charles A. Cuenod, Hamze B, Tubiana Jm, Laredo Jd, and Bondeville Jm
- Subjects
Male ,medicine.medical_specialty ,Bone disease ,Osteoporosis ,Contrast Media ,Lumbar vertebrae ,Malignancy ,Sensitivity and Specificity ,Thoracic Vertebrae ,Diagnosis, Differential ,Heterocyclic Compounds ,Predictive Value of Tests ,medicine ,Organometallic Compounds ,Humans ,Radiology, Nuclear Medicine and imaging ,Retrospective Studies ,Lumbar Vertebrae ,Spinal Neoplasms ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Vertebra ,medicine.anatomical_structure ,Fractures, Spontaneous ,Logistic Models ,Thoracic vertebrae ,Acute Disease ,Spinal Fractures ,Female ,Radiology ,Differential diagnosis ,business - Abstract
To distinguish malignant from osteoporotic acute vertebral collapses.Sixty-three osteoporotic and 30 malignant vertebral collapses were studied in 51 patients (aged 33-88 years) with T1-weighted magnetic resonance (MR) images (n=93), gadolinium-enhanced T1-weighted images (n=72), and T2-weighted images (n=53).Four findings were suggestive of osteoporosis: retropulsion of a bone fragment (10 osteoporotic cases vs 0 malignant cases), preservation of normal signal intensity on T1-weighted images (43 vs four), return to normal signal intensity after gadolinium injection (42 vs four) with horizontal bandlike patterns, and isointense vertebrae on T2-weighted images (28 vs two). Six findings were suggestive of malignancy: convex posterior cortex (21 malignant cases vs four osteoporotic cases), epidural mass (24 vs 0), diffuse low signal intensity within the vertebral body on T1-weighted images (23 vs 12) and in the pedicles (24 vs four), high or inhomogeneous signal intensity after gadolinium injection (17 vs 0) and on T2-weighted images (17 vs 0).Gadolinium-enhanced and unenhanced MR images are useful in the differentiation of vertebral collapses.
- Published
- 1996