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Supplemental Material for Phytic acid regulates proliferation of colorectal cancer cells by downregulating NF-kB and β-catenin signalling by Jianyu Feng, Yandong Liu, Chunnan Zhang, Menglin Ji and Cuiyun Li in European Journal of Inflammation.

BACKGROUND: This study aimed to explore the effects of Kangdaxin oral liquid on myocardial fibrosis in heart failure with preserved ejection fraction (HFpEF) rats. METHODS: A total of 30 Sprague Dawley (SD) rats were randomly divided into 3 groups Sham operation group (Sham), HFpEF group (HFpEF), and HFpEF with drug intervention group (HFpEF + I). Rats in HFpEF + I group were given Kangdaxin oral liquid at a dose of 2.7 mL/(kg·d). After modeling or treatment, the value of E/A and E/e' in each group of rats were measured by echocardiography. The N-terminal pro b-type natriuretic peptide (NT-proBNP) level was determined by enzyme-linked immunosorbent assay (ELISA). Heart weight/body mass index (Hw/W) and left ventricular weight/body mass index (LVw/W) were calculated after the rats were sacrificed; the transforming growth factor-β1 (TGF-β1) protein expression level in cardiac tissue was detected by western blot. RESULTS: Compared with sham group, the values of diastolic function item (E/A) and mitral annular early diastolic velocity (E/e') in HFpEF group were significantly decreased, and the level of NT-proBNP was significantly increased (P

Electrical properties of Si-doped (Al0.5Ga0.5)0.5In0.5P grown by atmospheric-pressure metalorganic chemical vapor deposition (MOCVD) under a wide range of growth conditions were investigated. The carrier concentrations of Si-doped AlGaInP increase with increasing mole fraction of dopant and growth temperature with activation energy of 2.2 eV, respectively. The VIII ratio has a strong effect on the electrical and optical properties in Si-doped AlGaInP. When the VIII ratio was varied from 50 to 200, the electron concentration, n, of Si-doped AlGaInP decreased with increasing VIII ratio and a sharp X-ray diffraction peak (full width at half maximum of 60 arc sec at a VIII ratio of 200) was obtained. Also found was a decrease in the Al content of the alloy with increased silane concentration for a constant group VIII ratio.

In this paper, an online hand-drawn graphic symbol recognition algorithm based on hidden Markov models is presented. A rearrangement strategy is applied to the hand-drawn symbol points in order to alleviate the influence of the difference in drawing sequence. Based on rearranged drawing points, global distance measure and local angle feature are extracted as the feature vector. After the quantization, a discrete HMM is used as the core recognizer. The experiment shows the recognition rate of our system can be above 85%.