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3. The progress in our understanding of CIN in breast cancer research

Author

Liao, Yu-Yang and Cao, Wen-Ming

Subjects
Cancer Research, Oncology
Abstract

Chromosomal instability (CIN) is an important marker of cancer, which is closely related to tumorigenesis, disease progression, treatment efficacy, and patient prognosis. However, due to the limitations of the currently available detection methods, its exact clinical significance remains unknown. Previous studies have demonstrated that 89% of invasive breast cancer cases possess CIN, suggesting that it has potential application in breast cancer diagnosis and treatment. In this review, we describe the two main types of CIN and discuss the associated detection methods. Subsequently, we highlight the impact of CIN in breast cancer development and progression and describe how it can influence treatment and prognosis. The goal of this review is to provide a reference on its mechanism for researchers and clinicians.

Published
2023

4. The gene spectrum of thalassemia in Yangjiang of western Guangdong Province

Author

Liang, Hong-Feng, Liang, Wei-Min, Xie, Wen-Guang, Lin, Fen, Liu, Li-Li, Li, Lie-Jun, Ge, Yi-Yuan, Lu, Min, Liao, Yu-Wei, Zeng, Guang-Kuan, Yao, Jin-Xiu, Situ, Jing-Wei, and Yang, Li-Ye

Subjects
Genetics, Molecular Medicine, Genetics (clinical)
Abstract

Background: Thalassemia presents a higher incidence in southern China. The objective of this study is to analyze the genotype distribution of thalassemia in Yangjiang, a western city of Guangdong Province in China.Methods: The genotypes of suspected cases with thalassemia were tested by PCR and reverse dot blot (RDB). Unidentified rare thalassemia genotypes of the samples were further ascertained by PCR and direct DNA sequencing.Results: Among 22467 suspected cases with thalassemia, 7658 cases were found with thalassemia genotypes using our PCR-RDB kit. Among these 7658 cases, 5313 cases were found with α-thalassemia (α-thal) alone, --SEA/αα was the most common genotype, accounting for 61.75% of α-thal genotypes, and the following mutations were found: α3.7/αα, -α4.2/αα, αCSα/αα, αWSα/αα, and αQSα/αα. A total of 2032 cases were found with β-thalassemia (β-thal) alone. βCD41-42/βN, βIVS−II−654/βN, and β−28/βN accounted for 80.9% of all β-thal genotypes, and the following genotypes were found: βCD17/βN, βCD71-72/βN, and βE/βN. Compound heterozygotes of β-thal and β-thalassemia homozygotes were identified in 11 and five cases, respectively, in this study. α-thal combined with β-thal was identified in 313 cases, showing 57 genotype combinations of the coincidence of both Hb disorders; one extreme patient had a genotype of --SEA/αWSα and βCD41-42/β−28. In addition, four rare α-mutations (--THAI, HKαα, Hb Q-Thailand, and CD31 AGG>AAG) and six rare β-mutations (CD39 CAG>TAG, IVS-Ⅱ-2 (−T), −90(C>T), Chinese Gγ+(Aγδβ)0, CD104 (-G), and CD19 A>G) were also found in this study population.Conclusion: This study provided detailed genotypes of thalassemia in Yangjiang of western Guangdong Province in China and reflected the complexity of genotypes in this high-prevalence region, and this would be valuable for diagnosis and counseling for thalassemia in this area.

Published
2023

6. Unveiling the Growth Mechanism of Faceted Primary Al2Cu with Complex Morphologies During Solidification

Author

Naifang Zhang, Qiaodan Hu, Zongye Ding, Jian Qiao, Jingwei Yang, Fan Yang, Wenquan Lu, Tianxing Yang, Liao Yu, and Jianguo Li

Subjects
Coalescence (physics), Materials science, Metals and Alloys, Intermetallic, Industrial and Manufacturing Engineering, Surface energy, Synchrotron, Strain energy, law.invention, Chemical physics, law, Metallic materials, Perpendicular, Electron backscatter diffraction
Abstract

The growth characteristic of primary faceted Al2Cu intermetallic compounds (IMCs) during solidification was observed directly by synchrotron radiography. The formation and transition mechanisms of Al2Cu IMCs with diverse morphologies were elucidated by first-principle calculations combined with electron backscatter diffraction analysis. The Al2Cu crystals preferred to grow along the [001] direction and were bounded by {110} planes with the lowest surface energy. The faceted Al2Cu rod-like clusters consisted of multiple crystals with complete rod, hollowness and partial sides, which was attributed to the increase in strain energy and solute redistribution during solidification. The faceted Al2Cu with branches was characteristic with the perpendicular relationship between the main branches and side steps and partial coalescence at the junction, which was ascribed to the continuous propagation and growth of newly formed crystals along the diagonal direction.

Published
2021

7. Investigating the Mechanism of Action of Frankincense against Drug- Induced Liver Injury Using Network Pharmacology and Molecular Docking

Author

Yang Qian, Zhao Chao, Li Rui-li, Wen Ai-dong, Wanga Wen-jun, Wang Jingwen, Sun Lian, Ding Yi, and Liao Yu-cheng

Subjects
Drug, Liver injury, Chemistry, media_common.quotation_subject, Pharmaceutical Science, Frankincense, Pharmacology, medicine.disease, Mechanism of action, Network pharmacology, Drug Discovery, medicine, Molecular Medicine, medicine.symptom, media_common
Abstract

Background: Frankincense has been used as a traditional medicine in many countries. It is an important herb with multiple targets and therapeutic effects, including liver protection. However, its mechanism of action in drug-induced liver injury (DILI) remains unknown. Objective: The purpose of this work was to elucidate the active components, core genes, and molecular mechanism of frankincense in DILI through network pharmacology and molecular docking approaches. Methods: The active components of frankincense and its target genes were obtained from the BATMAN-TCM database, and the DILI target genes were obtained from the GeneCards and Drug- Bank databases. Cytoscape was used to create the compound-shared gene target network. STRING and DAVID software were used to analyze key targets and pathway enrichment. Autodock Vina software was used for molecular docking. Results: Network analysis identified 16 compounds in frankincense and 103 target genes highly related to DILI. The core genes in the protein-protein interaction network are INS, IL6, TP53, TNF, SRC, PTGS2, IL1B, CAT, IL10, and IGF1. Furthermore, GO and KEGG pathway enrichment analyses indicated that the effect of frankincense on DILI is related to positive regulation of transcription from RNA polymerase II promoter and inflammatory response. Core pathways such as the HIF-1, TNF, FoxO, PI3K-Akt, and the sphingolipid signaling pathway are closely related to DILI. Conclusion: This study revealed the chemical constituents and pharmacological effects of frankincense and unveiled potential DILI healing targets. This study could provide insights for further development of drugs that specifically target DILI.

Published
2021

8. Long-term maxillary anteroposterior changes following maxillary protraction with or without expansion: a systematic review and meta-analysis

Author

Lee, Wei-Cheng, Shieh, Yi-Shing, Liao, Yu-Fang, Lee, Cho-Hao, and Huang, Chiung

Subjects
Medicine and Health Sciences
Abstract

Although maxillary protraction with or without expansion is a widely known orthopedic treatment in young skeletal Class III patients, the skeletal effect on the reinforcement of maxillary growth over time from the traditional methods has been debated and remains controversial. In addition, in the long-term observation, the study results were inconsistent and there is limited data regarding the outcomes of long term changes on the maxilla. The aim of this meta-analysis was to assess the effectiveness of the long-term changes on the maxilla through a face mask (FM) with or without rapid maxillary expansion (RME) in the skeletal CIII child or young adolescent.

Published
2022
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9. Effect of cooling rate on the 3D morphology of the proeutectic Al3Ni intermetallic compound formed at the Al/Ni interface after solidification

Author

Naifang Zhang, Jianguo Li, Fan Yang, Liao Yu, Qiaodan Hu, Zongye Ding, Sheng Cao, and Wenquan Lu

Subjects
Materials science, Morphology (linguistics), Polymers and Plastics, Gradual transition, Mechanical Engineering, Metals and Alloys, Intermetallic, Synchrotron, law.invention, Cooling rate, Mechanics of Materials, law, Phase (matter), Materials Chemistry, Ceramics and Composites, Composite material, Groove (music), Electron backscatter diffraction
Abstract

Effect of cooling rate on the 3D morphology and the growth mechanism of the proeutectic Al3Ni intermetallic compound (IMC) that forms at the Al/Ni interface after solidification was investigated by synchrotron X-ray microtomography in combination with EBSD analysis. The proeutectic Al3Ni phase that forms under an average cooling rate of 0.1 K s−1 shows a characteristic faceted growth behavior and presents a typical 3D morphology as partially hollow quadrangular prisms. On the contrary, that forms under an average cooling rate of 10 K s−1 shows complicated dendritic morphology with asymmetrically distributed arms and faceted V-shape groove at the distal end, indicating a gradual transition of the growth behavior from non-faceted to faceted during the solidification process. These results reveal that the morphology of the proeutectic Al3Ni is highly sensitive to the solidification condition so that fine control of the desired morphology may be achieved by carefully manipulating the cooling profile.

Published
2021

10. The complete mitochondrial genome of the common strain black carp (Cyprinus carpio var. baisenensis)

Author

Shengyan Su, Chengfeng Zhang, Opeoluwa Christiana, Liao Yu, Yongkai Tang, and Peipei Wang

Subjects
0106 biological sciences, 0301 basic medicine, Genetics, Mitochondrial DNA, biology, Phylogenetic tree, Origin of replication, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, Genome, Cyprinus, 03 medical and health sciences, 030104 developmental biology, Black carp, Heavy strand, Molecular Biology, Gene
Abstract

The common strain black carp (Cyprinus carpio var. baisenensis), known for its black skin is cultured in the integrated rice-agriculture system and non-escape property under torrential floods. The total mitogenome length of Cyprinus carpio var. baisenensis obtained in this study was 16,478bp, consisting of 13 protein-coding genes, 22 tRNA genes, 2rRNA genes (large and small), a light strand origin of replication, and one major non-coding region. By providing the complete mitochondrial genomes of Cyprinus carpio var. baisenensis, we will further understand the phylogenetic relationships within genus.

Published
2021

11. Recent Progress in Metallurgical Bonding Mechanisms at the Liquid/Solid Interface of Dissimilar Metals Investigated via in situ X-ray Imaging Technologies

Author

Naifang Zhang, Qiaodan Hu, Wenquan Lu, Liao Yu, Jianguo Li, and Zongye Ding

Subjects
010302 applied physics, Interconnection, Materials science, business.industry, Interface (computing), Metallurgy, Metals and Alloys, Intermetallic, 02 engineering and technology, 021001 nanoscience & nanotechnology, Microstructure, 01 natural sciences, Industrial and Manufacturing Engineering, S interface, Soldering, 0103 physical sciences, Microelectronics, Electronics, 0210 nano-technology, business
Abstract

The liquid/solid (L/S) interface of dissimilar metals is critical to the microstructure, mechanical strength, and structural integrity of interconnects in many important applications such as electronics, automotive, aeronautics, and astronautics, and therefore has drawn increasing research interests. To design preferential microstructure and optimize mechanical properties of the interconnects, it is crucial to understand the formation and growth mechanisms of diversified structures at the L/S interface during interconnecting. In situ synchrotron radiation or tube-generated X-ray radiography and tomography technologies make it possible to observe the evolution of the L/S interface directly and therefore have greatly propelled the research in this field. Here, we review the recent progress in understanding the L/S interface behaviors using advanced in situ X-ray imaging techniques with a particular focus on the following two issues: (1) interface behaviors in the solder joints for microelectronic packaging including the intermetallic compounds (IMCs) during reflow, Sn dendrites, and IMCs during solidification and reflow porosities and (2) growth characteristics and morphological transition of IMCs in the interconnect of dissimilar metals at high temperature. Furthermore, the main achievements and future research perspectives in terms of metallurgical bonding mechanisms under complex conditions with improved X-ray sources and detectors are remarked and discussed.

Published
2021

12. Development of Personalized Learning Resources Recommendation System Based on Knowledge Graph

Author

Liao Yu, Yuan Ziheng, Huang Hui, WU Mengmeng, Wnag Yingfeng, and XU Xiaoli

Subjects
Mode (computer interface), Information retrieval, Computer science, Graph (abstract data type), Context (language use), Personalized learning, Recommender system, Curriculum, Session (web analytics), Market fragmentation
Abstract

This study focuses on how to efficiently and accurately recommend personalized learning resources for users when they are in the face of massive learning resources. A recommendation system is developed with software engineering methods. Knowledge graph technology is integrated in the system; curriculum knowledge graphs are constructed to solve the problems of semi-structured data storage and knowledge fragmentation. Two kinds of recommendation methods are adopted to achieve the goal of learners' personalized learning, one is Euclidean distance recommendation algorithm based on user behavior graph library, the other is learning mode recommendation algorithm and sequential mode recommendation algorithm based on user session library. The recommendation system maintains the interpret-ability and the accuracy of recommendation based on user historical behavior data; and realizes recommendation based on user session library in the context of lacking users’ historical data.

Published
2021

13. Flexible Electronics Directly Written with an Ultrastable Ballpoint Pen Based on a Graphene Nanosheets/MWCNTs/Carbon Black Nanocomposite

Author

Xin Wang, Jun Qian, Yufei Tian, Liao Yu, Ma Xiaohua, and Zhao Meijun

Subjects
Materials science, Nanocomposite, Graphene, chemistry.chemical_element, Carbon black, Flexible electronics, Electronic, Optical and Magnetic Materials, law.invention, Chemical engineering, chemistry, law, Conductive ink, Materials Chemistry, Electrochemistry, Electrical conductor, Carbon, Mass fraction
Abstract

A writable ultrafine water-based conductive ink with excellent stability and no harmful gas emission was prepared. The mass fraction of carbon conductive particles was 4.95%, and the mean median pa...

Published
2020

14. Intergrowth mechanism and morphology prediction of faceted Al3Ni formed during solidification by a spatial geometric model

Author

Naifang Zhang, Liao Yu, Fan Yang, Yihan Zhou, Sheng Cao, Qiaodan Hu, Wenquan Lu, Jianguo Li, and Zongye Ding

Subjects
Interconnection, Materials science, Polymers and Plastics, Mechanical Engineering, Metals and Alloys, Intermetallic, Crystal growth, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Boundary layer thickness, 01 natural sciences, Synchrotron, 0104 chemical sciences, law.invention, Crystal, Mechanics of Materials, law, Chemical physics, Materials Chemistry, Ceramics and Composites, 0210 nano-technology, Geometric modeling, Critical condition
Abstract

The interplay and intergrowth characteristic of faceted intermetallic compounds (IMCs) during solidification was originally investigated through the rod-like Al3Ni crystals in the liquid Al/solid Ni interconnection by using synchrotron radiography, and the diversified 3-D morphologies were reconstructed by synchrotron tomography. A spatial geometric model was established to effectively predict the diversified growth patterns of two spatial crystals. For the two overlapping Al3Ni crystals, the impeded crystal growth was divided into three different stages, decided by the hindrance form the other crystal. Further, the groove formed on the crystal surface is directly related to the solute redistribution under the critical condition of boundary layer thickness larger than two crystals distance. The closer distance and smaller crystal size indicate the deeper and larger groove, and the morphology changes from hemispheroid to hemi-ellipsoid with the increased opposite and interacted faces.

Published
2020

17. Mask2Hand: Learning to Predict the 3D Hand Pose and Shape from Shadow

Author

Chang, Li-Jen, Liao, Yu-Cheng, Lin, Chia-Hui, and Chen, Hwann-Tzong

Subjects
FOS: Computer and information sciences, Computer Vision and Pattern Recognition (cs.CV), Computer Science - Computer Vision and Pattern Recognition, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, ComputingMethodologies_COMPUTERGRAPHICS
Abstract

We present a self-trainable method, Mask2Hand, which learns to solve the challenging task of predicting 3D hand pose and shape from a 2D binary mask of hand silhouette/shadow without additional manually-annotated data. Given the intrinsic camera parameters and the parametric hand model in the camera space, we adopt the differentiable rendering technique to project 3D estimations onto the 2D binary silhouette space. By applying a tailored combination of losses between the rendered silhouette and the input binary mask, we are able to integrate the self-guidance mechanism into our end-to-end optimization process for constraining global mesh registration and hand pose estimation. The experiments show that our method, which takes a single binary mask as the input, can achieve comparable prediction accuracy on both unaligned and aligned settings as state-of-the-art methods that require RGB or depth inputs. Our code is available at https://github.com/lijenchang/Mask2Hand.

Published
2022
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18. Screen-Printed High-Performance Flexible Electrothermal Films Based on Three-Dimensional Intercalation Graphene Nanosheets/MWCNT/Carbon Black Composite

Author

Liao Yu, Ma Xiaohua, Zhao Meijun, Jun Qian, Yufei Tian, and Xin Wang

Subjects
Materials science, Graphene, Intercalation (chemistry), Composite number, Carbon black, Flexible electronics, law.invention, law, visual_art, visual_art.visual_art_medium, General Materials Science, Graphite, Composite material, Acrylic resin, Sheet resistance
Abstract

A liquid-phase stripping method was used to strip the graphite under the action of mechanical shear force to prepare graphene nanosheets (GNSs) on a large scale. Given the multicomponent composite conductive particles formed by GNSs with acid-treated MWCNTs (f-MWCNTs) and carbon black (CB), the three-dimensional (3D) intercalation electrothermal composite of GNSs/MWCNTs/CB with excellent conductivity and mechanical properties was prepared with water-based acrylic resin as a connector. Carbon particles (16.97 wt %) are found in the composite and the sheet resistance (Rs) is only 4 Ω sq-1 as f-MWCNTs and CB intercalations form a more stable 3D conducting medium between the GNSs. The flexible electrothermal film (2.5 cm × 2.5 cm) printed with the 3D intercalation GNSs/MWCNTs/CB composite had a saturation temperature (Ts) of 175 °C with an input of 3 V and lower power consumption (249.87 cm2 W-1). It only takes 10 s to reach Ts and the electrical performance is still intact under the pressure of 1 × 105 kPa. After being bent 2500 times (bending radius is 5 mm), the electrothermal performance of the flexible electrothermal film remained stable.

Published
2020

19. In Situ Analysis of Multiphase Compounds at the Liquid Al-Solid Cu Interface: Formation Sequence, Growth Kinetics and Critical Thickness

Author

Sheng Cao, Qiaodan Hu, Naifang Zhang, Wenquan Lu, Liao Yu, Tianxing Yang, Fan Yang, Jianguo Li, and Zongye Ding

Subjects
Range (particle radiation), Materials science, Diffusion, Metallurgy, Metals and Alloys, Substrate (electronics), Condensed Matter Physics, Chemical reaction, Synchrotron, law.invention, Chemical engineering, Mechanics of Materials, law, Phase (matter), Layer (electronics), Dissolution
Abstract

The dissolution of substrate and growth behavior of diversified IMCs at the liquid Al/solid Cu interface were in-situ observed through synchrotron radiography. The formation and growth characteristics of diversified layers at the interface were investigated, and the difference between the critical thicknesses of growing layers before new IMCs formation was determined. The primary IMCs formation during holding or solidification was achieved by controlling the Al amount and holding time. Three IMCs, e2, γ1 and β, formed sequentially at the interface during reactive diffusion, following by η2 and θ IMCs during solidification. The primary phase and IMCs formation sequence during diffusion reaction were effectively predicted from the driving force and consistent with the in-situ observation. The growth of e2 layer at the early stage and γ1 layer were dominated by chemical reaction, while the limited atoms diffusion based on a multiphase growth model resulted in the e2 and β growth deviating from a linear relationship. In addition, a larger concentration range of the lately formed phase and a smaller concentration range of the growing phase preferred an increasing critical thickness.

Published
2020

20. Effect of Si on the Growth Behavior of the Fe2Al5 Phase at Al-xSi(liquid)/Fe(solid) Interface During Holding by In-Situ Synchrotron Radiography

Author

Liao Yu, Qiaodan Hu, Xuan Ge, Sheng Cao, Wenquan Lu, Jianguo Li, Fan Yang, Zongye Ding, and Naifang Zhang

Subjects
010302 applied physics, In situ, Morphology (linguistics), Structural material, Materials science, Kinetics, Metallurgy, 0211 other engineering and technologies, Metals and Alloys, Analytical chemistry, Synchrotron radiation, 02 engineering and technology, Condensed Matter Physics, 01 natural sciences, Synchrotron, law.invention, Mechanics of Materials, law, Phase (matter), 0103 physical sciences, Dissolution, 021102 mining & metallurgy
Abstract

Effect of Si on the growth behavior of the Fe2Al5 phase formed at the Al-xSi(liquid)/Fe(solid) interface during holding was investigated by a synchrotron radiation real-time imaging technique. Results show that growth of the Fe2Al5 phase is accompanied by its simultaneous dissolution into the melt. Addition of Si inhibits the growth of Fe2Al5 to reduce its thickness and change its morphology. The growth and dissolution kinetics of the Fe2Al5 phase are discussed.

Published
2020

22. MoABank: An Integrated Database for Drug Mode of Action Knowledge

Author

Jiang Zhen-ran and Liao Yu-di

Subjects
Drug, 0303 health sciences, Computer science, media_common.quotation_subject, 030302 biochemistry & molecular biology, Biochemistry, 03 medical and health sciences, Computational Mathematics, Human–computer interaction, Genetics, Integrated database, Mode of action, Molecular Biology, 030304 developmental biology, media_common
Abstract

Background: With the declining trend of new drugs yield each year, more comprehensive knowledge of drug MoAs can help identify new applications of available drugs and discovery novel mechanism of drug action. Objective: Therefore, construction of a specialized drug mode of action (MoA) database is of paramount importance for new drug research & development. Methods: This paper introduces an integrated database for drug mode of action knowledge (MoABank). Results: This database can provide the knowledge about drug MoAs, targets, pathways, side effects and other drug-related information for researchers. Conclusion: We believe MoABank can make it more convenient for users to obtain the drug MoA information in the future.

Published
2019

23. High field antiferroelectric-like dielectric of poly(vinylidene fluoride-co-trifluoroethylene-co-chlorotrifluoroethylene)-graft-poly(styrene-methyl methacrylate) for high pulse capacitors with high energy density and low loss

Author

Zhicheng Zhang, Liao Yu, Jingjing Liu, and Jiani Liao

Subjects
Ferroelectric polymers, Materials science, Polymers and Plastics, Organic Chemistry, Bioengineering, 02 engineering and technology, Dielectric, 010402 general chemistry, 021001 nanoscience & nanotechnology, Methacrylate, 01 natural sciences, Biochemistry, 0104 chemical sciences, law.invention, Capacitor, chemistry.chemical_compound, Film capacitor, Chemical engineering, chemistry, law, Copolymer, Dielectric loss, Methyl methacrylate, 0210 nano-technology
Abstract

Dielectric polymer film capacitors with high energy density and low energy loss are highly desirable in compact electronic devices and high power density electric systems. To overcome the high dielectric loss of poly(vinylidene fluoride) based ferroelectric polymers, in this work, a series of antiferroelectric-like poly(vinylidene fluoride-co-trifluoroethylene-co-chlorotrifluoroethylene)-graft-poly(styrene-methyl methacrylate) (PVDF-MS) copolymers were successfully synthesized using an atom transfer radical polymerization procedure. The merits including the excellent miscibility of PMMA with both PSt and PVDF, and the promising insulating performance of PSt segments are combined in the resultant copolymers. The introduction of increased P(St-MMA) (MS) side chains leads to significantly enhanced energy density, low conduction loss and energy loss compared with the pristine P(VDF-TrFE-CTFE). The highest energy density of 17 J cm−3 and the discharge efficiency of 87% at 600 MV m−1 are achieved by the sample containing 28 wt% MS. The excellent dielectric and capacitive properties of the grafted copolymers offer a strategy for the synthesis of high dielectric polymer dielectrics with promising energy storage properties.

Published
2019

24. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1

Author

Liu, Xiangsheng, Jiang, Jinhong, Liao, Yu-Pei, Tang, Ivanna, Zheng, Emily, Qiu, Waveley, Lin, Matthew, Wang, Xiang, Ji, Ying, Mei, Kuo-Ching, Liu, Qi, Chang, Chong Hyun, Wainberg, Zev A, Nel, Andre E, and Meng, Huan

Subjects
autophagy, chemo‐immunotherapy, pancreatic cancer, Vaccine Related, PD‐1/PD‐L1 axis, Pancreatic Cancer, Orphan Drug, Rare Diseases, 5.1 Pharmaceuticals, Immunization, chemo-immunotherapy, irinotecan silicasome, Development of treatments and therapeutic interventions, Digestive Diseases, Cancer, PD-1/PD-L1 axis
Abstract

There is an urgent need to develop new life-prolonging therapy for pancreatic ductal adenocarcinoma (PDAC). It is demonstrated that improved irinotecan delivery by a lipid bilayer coated mesoporous silica nanoparticle, also known as a silicasome, can improve PDAC survival through a chemo-immunotherapy response in an orthotopic Kras-dependent pancreatic cancer model. This discovery is premised on the weak-basic properties of irinotecan, which neutralizes the acidic lysosomal pH in PDAC cells. This effect triggers a linked downstream cascade of events that include autophagy inhibition, endoplasmic reticulum stress, immunogenic cell death (ICD), and programmed death-ligand 1 (PD-L1) expression. ICD is characterized by calreticulin expression and high-mobility group box 1 (HMGB1) release in dying Kras-induced pancreatic cancer (KPC) cells, which is demonstrated in a vaccination experiment to prevent KPC tumor growth on the contralateral site. The improved delivery of irinotecan by the silicasome is accompanied by robust antitumor immunity, which can be synergistically enhanced by anti-PD-1 in the orthotopic model. Immunophenotyping confirms the expression of calreticulin, HMGB1, PD-L1, and an autophagy marker, in addition to perforin and granzyme B deposition. The chemo-immunotherapy response elicited by the silicasome is more robust than free or a liposomal drug, Onivyde. The silicasome plus anti-PD-1 leads to significantly enhanced survival improvement, and is far superior to anti-PD-1 plus either free irinotecan or Onivyde.

Published
2021

25. The complete mitochondrial genome of the common strain black carp (

Author

Peipei, Wang, Opeoluwa, Christiana, Liao, Yu, Chengfeng, Zhang, Shengyan, Su, and Yongkai, Tang

Subjects
Mitochondrial genome, integrated rice-agriculture, phylogenetic, Cyprinus carpio var. baisenensis, Mitogenome Announcement, Research Article
Abstract

ABTRACT The common strain black carp (Cyprinus carpio var. baisenensis), known for its black skin is cultured in the integrated rice-agriculture system and non-escape property under torrential floods. The total mitogenome length of Cyprinus carpio var. baisenensis obtained in this study was 16,478bp, consisting of 13 protein-coding genes, 22 tRNA genes, 2rRNA genes (large and small), a light strand origin of replication, and one major non-coding region. By providing the complete mitochondrial genomes of Cyprinus carpio var. baisenensis, we will further understand the phylogenetic relationships within genus.

Published
2021

26. Additional file 1 of A study on how using an interactive multimedia e-book improves teachers��� ability to teach evidence-based medicine depending on their seniority

Author

Liao, Yu-Hsuan, Tang, Kuo-Shu, Chen, Chih-Jen, Huang, Ying-Hsien, and Tiao, Mao-Meng

Subjects
InformationSystems_INFORMATIONINTERFACESANDPRESENTATION(e.g.,HCI), InformationSystems_INFORMATIONSYSTEMSAPPLICATIONS, Data_FILES, ComputingMilieux_COMPUTERSANDEDUCATION, ComputingMilieux_PERSONALCOMPUTING
Abstract

Additional file 1. The PowerPoint for the control group.

Published
2021
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27. Ferroelectric HfO$_2$ Memory Transistors with High-$��$ Interfacial Layer and Write Endurance Exceeding $10^{10}$ Cycles

Author

Tan, Ava Jiang, Liao, Yu-Hung, Wang, Li-Chen, Bae, Jong-Ho, Hu, Chenming, and Salahuddin, Sayeef

Subjects
FOS: Physical sciences, Applied Physics (physics.app-ph)
Abstract

We demonstrate ferroelectric (FE) memory transistors on a crystalline silicon channel with endurance exceeding $10^{10}$ cycles. The ferroelectric transistors (FeFETs) incorporate a high-$��$ interfacial layer (IL) of thermally grown silicon nitride (SiN$_x$) and a thin 4.5 nm layer of Zr-doped FE-HfO$_2$ on a $\sim$30 nm SOI channel. The device shows a $\sim$ 1V memory window in a DC sweep of just $\pm$ 2.5V, and can be programmed and erased with voltage pulses of $V_G= \pm$ 3V at a pulse width of 250 ns. The device also shows very good retention behavior. These results indicate that appropriate engineering of the IL layer could substantially improve FeFET device performance and reliability.

Published
2021
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28. sj-docx-2-tam-10.1177_17588359211022886 – Supplemental material for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer

Author

Ying, Hou-Qun, Sun, Fan, Liao, Yu-Cui, Cai, Dan, Yang, Ying, and Cheng, Xue-Xin

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-2-tam-10.1177_17588359211022886 for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer by Hou-Qun Ying, Fan Sun, Yu-Cui Liao, Dan Cai, Ying Yang and Xue-Xin Cheng in Therapeutic Advances in Medical Oncology

Published
2021
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29. sj-docx-1-tam-10.1177_17588359211022886 – Supplemental material for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer

Author

Ying, Hou-Qun, Sun, Fan, Liao, Yu-Cui, Cai, Dan, Yang, Ying, and Cheng, Xue-Xin

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tam-10.1177_17588359211022886 for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer by Hou-Qun Ying, Fan Sun, Yu-Cui Liao, Dan Cai, Ying Yang and Xue-Xin Cheng in Therapeutic Advances in Medical Oncology

Published
2021
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30. Additional file 1 of ATP and NADPH engineering of Escherichia coli to improve the production of 4-hydroxyphenylacetic acid using CRISPRi

Author

Shen, Yu-Ping, Liao, Yu-Ling, Lu, Qian, He, Xin, Yan, Zhi-Bo, and Liu, Jian-Zhong

Abstract

Additional file 1: Figure S1 Biosynthetic pathway of 4-hydroxyphenylacetic acid in the engineered Escherichia coli used in this study. Black: E. coli genes; red: Saccharomyces cerevisiae gene. PEP: phosphoenolpyruvate; E4P: D-erythrose 4-phosphate; DAHP: 3-deoxy-arabino-heptulonate 7-phosphate; DHQ: 3-dehydroquinate; DHS: 3-dehydroshikimate; EPSP: enolpyruvoyl-shikimate 3-phosphate. aroF/aroH/aroG: 3-deoxy-7-phosphoheptulonate synthase gene; aroB: 3-dehydroquinate synthase gene; aroD: 3-dehydroquinate dehydratase gene; aroE: shikimate dehydrogenase gene; aroK/aroL: shikimate kinase gene; aroA: 3-phosphoshikimate 1-carboxyvinyltransferase gene; aroC: chorismate synthase gene; tyrA: chorismate mutase/prephenate dehydrogenase gene; pheA: chorismate mutase/prephenate dehydratase gene; ARO10: phenylpyruvate decarboxylase gene from S. cerevisiae; feaB: phenylacetaldehyde dehydrogenase gene. Figure S2. CRISPRi-based gene repression. (A) Block transcription initiation via competition with RNA polymerase (RNAP) or transcription factors (TFs) for binding to promoter DNA. When the dCas9-sgRNA complex binds to the promoter sequence or the cis-acting transcription factor binding site (TFBS), it can block transcription initiation by sterically inhibiting the binding of RNAP or transcription factors (TFs). Silencing of transcription initiation is effective for both nontemplate (NT) and template (T) DNA strand. (B) Block transcription elongation by targeting the CDS and preventing the transcription elongation complex from passing. When the dCas9-sgRNA complex binds to the NT DNA strand of the UTR or the protein coding region, it can repress gene expression by blocking the elongating RNAPs. Silencing of transcription elongation is effective only for the NT DNA strand. Additionally, the interference is negatively correlated with the distance of the target site from the transcription start site. Thus, to achieve better repression, target sites within the 5’ end of the gene should be selected. Figure S3. Effect of repression of NADHP-consuming enzyme-encoding genes on the production of 4HPAA. Figure S4. Effect of repression of ATP-consuming enzyme-encoding genes on the production of 4HPAA. Figure S5. (A) The 4HPAA tolerance of E. coli 4HPAA (■) and E. coli 4HPAA-GS-2-4 (●). Cells were cultured in the presence of 35.0 g/L 4HPAA at 30°C and 200 rpm for 24 h. (B) The 4HPAA production (gray bar) and growth (white bar) of E. coli 4HPAA and E. coli 4HPAA-GS-2-4. Figure S6. Plasmid maps used for CRISPRi in this study. Table S1. Transcriptional levels of the selected genes in E. coli 4HPAA-2 after CRISPRi-based repression compared with those without sgRNAs. Table S2. Primers used in this study.

Published
2021
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31. sj-pdf-3-tam-10.1177_17588359211022886 – Supplemental material for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer

Author

Ying, Hou-Qun, Sun, Fan, Liao, Yu-Cui, Cai, Dan, Yang, Ying, and Cheng, Xue-Xin

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-pdf-3-tam-10.1177_17588359211022886 for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer by Hou-Qun Ying, Fan Sun, Yu-Cui Liao, Dan Cai, Ying Yang and Xue-Xin Cheng in Therapeutic Advances in Medical Oncology

Published
2021
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32. sj-pdf-3-tam-10.1177_17588359211022886 – Supplemental material for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer

Author

Ying, Hou-Qun, Sun, Fan, Liao, Yu-Cui, Cai, Dan, Yang, Ying, and Cheng, Xue-Xin

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-pdf-3-tam-10.1177_17588359211022886 for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer by Hou-Qun Ying, Fan Sun, Yu-Cui Liao, Dan Cai, Ying Yang and Xue-Xin Cheng in Therapeutic Advances in Medical Oncology

Published
2021
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33. sj-docx-1-tam-10.1177_17588359211022886 – Supplemental material for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer

Author

Ying, Hou-Qun, Sun, Fan, Liao, Yu-Cui, Cai, Dan, Yang, Ying, and Cheng, Xue-Xin

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tam-10.1177_17588359211022886 for The value of circulating fibrinogen-to-pre-albumin ratio in predicting survival and benefit from chemotherapy in colorectal cancer by Hou-Qun Ying, Fan Sun, Yu-Cui Liao, Dan Cai, Ying Yang and Xue-Xin Cheng in Therapeutic Advances in Medical Oncology

Published
2021
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34. Relative Symmetric Reductions under Multi-Choice Non-Transferable-Utility Situations

Author

Liao, Yu-Hsien

Subjects
non-transferable-utility situation, the replicated core, relative symmetric reducing behavior, reduction axiom, General Mathematics, Computer Science (miscellaneous), Engineering (miscellaneous)
Abstract

In many game-theoretical results, the reduction axiom and its converse have been regarded as important requirements under axiomatic processes for solutions. However, it is shown that the replicated core counters a specific (inferior) converse reduction axiom under multi-choice non-transferable-utility situations. Thus, two modified reductions and relative properties of the reduction axiom and its converse are proposed to characterize the replicated core in this article.The main methods and relative results are as follows. First, two different types of reductions are proposed by focusing on both participants and participation levels under relative symmetric reducing behavior. Further, relative reduction axioms and their converse are adopted to characterize the replicated core.

Published
2022

35. A comparative experimental study of two multi-robot olfaction methods: Towards locating time-varying indoor pollutant sources

Author

Fei Li, Fei Liu, Hao Cai, Mingrui Jiang, Jiang Wenqing, Yang Zhou, Guo Xun, and Liao Yu

Subjects
Pollutant, Environmental Engineering, Computer science, Geography, Planning and Development, Real-time computing, Swarm behaviour, Particle swarm optimization, Building and Construction, computer.file_format, Source localization, Robot, Overall performance, Executable, Focus (optics), computer, Civil and Structural Engineering
Abstract

Locating the source of indoor pollutants/hazardous substances is essential to ensure the health and safety of indoor personnel. The existing studies on source localization using robots rarely focus on time-varying sources whose release rate changes with time. However, in practical applications, time-varying sources are ubiquitous, and it is usually more difficult to locate a time-varying source than a constant source with a constant release rate. This study aims to locate time-varying sources in a real-world indoor environment by using our two newly proposed two multi-robot olfaction methods, namely, the improved particle swarm optimization (IPSO) method and the improved whale swarm algorithm (IWOA) method. To this end, we developed a source localization system composed of three robots and compiled the IPSO and IWOA methods into executable programs. This study conducted 160 experiments for four scenarios, which included two time-varying source types (periodic source and decaying source) and two source locations. In each scenario, 20 independent experiments were conducted for each method. For all four scenarios, the mean success rates of the IPSO and IWOA methods were 80% and 91%, respectively, indicating that both methods have the potential to locate indoor time-varying sources. In terms of the success rate, locating efficiency and locating accuracy, the overall performance of the IWOA method was better than that of the IPSO method. The advantages of the IWOA method were its success rate and locating accuracy, while the disadvantage was its locating efficiency.

Published
2022

36. RETRACTED ARTICLE: A sensitive N-nitroso-N-methylurea sensor based on graphene-like BC3 and NC3 layers

Author

Li Qiang, Liao Yu, and Liu Zongxin

Subjects
Nanostructure, Materials science, 010304 chemical physics, Sensing applications, Graphene, Biophysics, 010402 general chemistry, Condensed Matter Physics, Photochemistry, 01 natural sciences, 0104 chemical sciences, law.invention, law, 0103 physical sciences, Density functional theory, Physical and Theoretical Chemistry, Molecular Biology
Abstract

In recent years, two-dimensional nanostructures have become some of the most interesting to be studied for sensing applications. Novel two-dimensional layers, denoted by BC3 and NC3 layers, have be...

Published
2020

37. A micromagnetic study of the switching dynamics of the BiFeO$_3$/CoFe heterojunction

Author

Liao, Yu-Ching, Nikonov, Dmitri E., Dutta, Sourav, Chang, Sou-Chi, Hsu, Chia-Sheng, Young, Ian A., and Naeemi, Azad

Subjects
Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences
Abstract

The switching dynamics of a single-domain BiFeO3/CoFe heterojunction is modeled and key parameters such as interface exchange coupling coefficient are extracted from experimental results. The lower limit of the magnetic order response time of CoFe in the BiFeO3/CoFe heterojunction is theoretically quantified to be on to the order of 100 ps. Our results indicate that the switching behavior of CoFe in the BiFeO3/CoFe heterojunction is dominated by the rotation of the Neel vector in BiFeO3 rather than the unidirectional exchange bias at the interface. We also quantify the magnitude of the interface exchange coupling coefficient J_int to be 0.32 pJ/m by comparing our simulation results with the giant magnetoresistance (GMR) curves and the magnetic hysteresis loop in the experiments. To the best of our knowledge, this is the first time that J_int is extracted quantitatively from experiments. Furthermore, we demonstrate that the switching success rate and the thermal stability of the BiFeO3/CoFe heterojunction can be improved by reducing the thickness of CoFe and increasing the length to width aspect ratio of the BiFeO3/CoFe heterojunction. Our theoretical model provides a comprehensive framework to study the magnetoelectric properties and the manipulation of the magnetic order of CoFe in the BiFeO3/CoFe heterojunction.

Published
2020
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38. Comparison of the Ectopic Bone Formation Ability Between Col I/HA and HA/β-TCP Artificial Bone in Mice

Author

Liao Yu, Lijia Cheng, Tian Yu, Zeng Yile, Xie Xinrong, Jun Wan, and Zheng Shi

Subjects
Artificial bone, Chemistry, 0206 medical engineering, 0202 electrical engineering, electronic engineering, information engineering, Biomedical Engineering, Medicine (miscellaneous), 020201 artificial intelligence & image processing, Bioengineering, 02 engineering and technology, 020601 biomedical engineering, Ectopic bone formation, Biotechnology, Cell biology
Published
2017

41. Effect of Sodium Trimetaphosphate on Chitosan-Methylcellulose Composite Films: Physicochemical Properties and Food Packaging Application

Author

Hongxia Wang, Wu Ailiang, Fuyuan Ding, Liao Yu, Bing Li, and Jun Qian

Subjects
Preservative, Materials science, Polymers and Plastics, Composite number, Sodium trimetaphosphate, macromolecular substances, chitosan/methylcellulose composite film, Article, Chitosan, lcsh:QD241-441, chemistry.chemical_compound, antibacterial activity, lcsh:Organic chemistry, Ultimate tensile strength, Solubility, sodium trimetaphosphate, Wax, physicochemical property, technology, industry, and agriculture, General Chemistry, Food packaging, chemistry, Chemical engineering, visual_art, visual_art.visual_art_medium, food packaging
Abstract

Environmentally friendly food packaging currently attracts much interest. Sodium trimetaphosphate (STMP) finds specialized applications in food, but it is rarely used as a crosslinking agent. In this study, STMP was used as a crosslinking agent to prepare chitosan/methylcellulose composite films. Both antibacterial and physicochemical properties of the composite film were improved by crosslinking with STMP. The crosslinked films, with good antibacterial activity (~99%), had increased tensile strength, a higher elongation at break, a lower swelling ratio and solubility, and a lower enzymatic degradation than the non-crosslinked films. Furthermore, the crosslinked films showed an excellent preservative effect on fresh-cut wax gourd after three days at room temperature. The obtained films crosslinked by STMP can be potentially applied to the food industry, such as food functional packaging, providing a novel alternative to traditional plastic packages.

Published
2019

43. Bipolar electric field switching of perpendicular magnetic tunnel junctions through voltage controlled exchange coupling

Author

Zhang, Delin, Bapna, Mukund, Jiang, Wei, de Sousa, Duarte Pereira, Liao, Yu-Ching, Zhao, Zhengyang, Lv, Yang, Sahu, Protyush, Lyu, Deyuan, Naeemi, Azad, Low, Tony, Majetich, Sara A, and Wang, Jian-Ping

Subjects
Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences, Physics - Applied Physics, Applied Physics (physics.app-ph)
Abstract

Perpendicular magnetic tunnel junctions (p-MTJs) switched utilizing bipolar electric fields have extensive applications in energy-efficient memory and logic devices. Voltage-controlled magnetic anisotropy linearly lowers the energy barrier of ferromagnetic layer via electric field effect and efficiently switches p-MTJs only with a unipolar behavior. Here we demonstrate a bipolar electric field effect switching of 100-nm p-MTJs with a synthetic antiferromagnetic free layer through voltage-controlled exchange coupling (VCEC). The switching current density, ~1.1x10^5 A/cm^2, is one order of magnitude lower than that of the best-reported spin-transfer torque devices. Theoretical results suggest that electric field induces a ferromagnetic-antiferromagnetic exchange coupling transition of the synthetic antiferromagnetic free layer and generates a field-like interlayer exchange coupling torque, which cause the bidirectional magnetization switching of p-MTJs. A preliminary benchmarking simulation estimates that VCEC dissipates an order of magnitude lower writing energy compared to spin-transfer torque at the 15-nm technology node. These results could eliminate the major obstacle in the development of spin memory devices beyond their embedded applications., Comment: 22 pages, 4 figures

Published
2019
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44. Preparation of HTLcs from Magnesium Desulfurization Residues and their Catalytic Performance in Degradation of Waste Polyester

Author

Ting Xu, Liao Yu Wei, Ming Yu Gu, Dan Zhao, Guang Ai Zhu, and Yan Mao Dong

Subjects
Thermogravimetric analysis, Materials science, Mechanical Engineering, Infrared spectroscopy, Condensed Matter Physics, Catalysis, law.invention, Flue-gas desulfurization, Polyester, Differential scanning calorimetry, Mechanics of Materials, law, Organic chemistry, General Materials Science, Calcination, Fourier transform infrared spectroscopy, Nuclear chemistry
Abstract

To recycle the solid wastes, the hydrotalcite-like compounds (HTLcs) were prepared from the magnesia flue gas desulfurization residues (MFGDR). The HTLcs as prepared and the products from degradation of Poly (ethylene terephthalate) (PET) were characterized by thermogravimetric analysis (TG) , x-ray powder diffraction (XRD) , fourier transform infrared spectrometer (FTIR) and differential scanning calorimetry (DSC) methods. Effects of calcining temperature and alkaline of solution on the structure and performance of HTLcs were studied. The main product of alcoholysis of PET was bis-hydroxyethyl terephthalate (BHET). The catalyst shows a potential application in solid waste treatment and recycle.

Published
2016

45. Monthly Power Market Bidding Optimal Strategy Considering Carbon Trading Risks

Author

Liao Yu, Yu Jie, Liu Junqi, Liu Li-li, Zhou Wenhuan, and Li Peng

Subjects
business.industry, 020209 energy, Total revenue, 02 engineering and technology, Bidding, AC power, Microeconomics, Independent Power Producer, Generalized entropy index, Expected shortfall, ComputingMethodologies_SYMBOLICANDALGEBRAICMANIPULATION, 0202 electrical engineering, electronic engineering, information engineering, Economics, Entropy (information theory), business, Risk management
Abstract

With the development of the national carbon trading market, the bidding strategy of Independent Power Producer (IPP) considering carbon trading is paid more and more attention. In the carbon trading market., IPP would face the risk of uncertainty of carbon trading prices. Using the principle of risk management theory in financial field., this paper presents conditional value at risk in carbon trading market (CRM-CVaR). Based on this risk measurement index., IPP monthly bidding optimal mathematics model is established. Simulation cases compare IPP bidding optimal strategy considering CRM-CVaR with non considering this index. Meanwhile., IPP comprehensive income entropy index is defined to measure the uniformity of the distribution of the IPP total revenue. It is shown by the numerical results that the algorithm is effective and can give IPP valuable bidding strategy.

Published
2018

46. A hybrid positioning method for multi-robot simultaneous location and mapping

Author

Yanbo Wang, Junqin Lin, Binyan Liang, Liao Yu, and Zhihong Chen

Subjects
0209 industrial biotechnology, Robot kinematics, Computer science, business.industry, Mobile robot, 02 engineering and technology, Simultaneous localization and mapping, Identification (information), 020901 industrial engineering & automation, 0202 electrical engineering, electronic engineering, information engineering, Six degrees of freedom, Robot, 020201 artificial intelligence & image processing, Computer vision, Artificial intelligence, business
Abstract

Navigating in a GPS-disabled environment is one of the basic tasks of autonomous mobile robots. Our research focuses on the topic that using a multi-robot simultaneous location and mapping (SLAM) to detect the surrounding environment. A new multi-robot SLAM framework is proposed. Firstly, each mobile robot is positioned with six degrees of freedom using cooperative identification, and then the data correlation between sub-maps is used to optimize the result of mutual positioning. Finally, sub-maps are merged for a consistent global map. Experimental results show that this method can achieve global map reconstruction, and can get more accurate results than single-robot SLAM.

Published
2018

47. Robot Arm Dynamics Control Based on Deep Learning and Physical Simulation

Author

Zhihong Chen, Tongtong Li, Yanbo Wang, Binyan Liang, and Liao Yu

Subjects
Computer science, business.industry, Deep learning, 02 engineering and technology, 010501 environmental sciences, 01 natural sciences, Computer Science::Robotics, Vehicle dynamics, 0202 electrical engineering, electronic engineering, information engineering, Robot, Torque, 020201 artificial intelligence & image processing, Artificial intelligence, business, Robotic arm, Dynamic method, Simulation, 0105 earth and related environmental sciences
Abstract

General robot arm dynamics is calculated by building robot arm physical model and calculating Newton-Euler formula. In the process of dynamic modeling, the accuracy of robot dynamic control will be affected by many factors, such as estimation of dynamic parameters, simplification of robot model, inaccurate parameters of friction model. In this paper, we proposal a method of calculating robot dynamics using deep learning networks and physical simulation. The deep learning network implement an end-to-end method to calculate robot dynamics. It means that the robot arm modeling process is not required. The robot arm physical simulation based on physical engine is carried out, and the deep learning network online training system is constructed by simultaneously communicating with the physical simulation through Socket communication. The experimental data shows that the maximum error of the joint torque calculation is 15.8% and 94.7% of the joint torque error is less than 10%. The calculation results of this method are approximately the same as those traditional dynamic method. However, the work presented in this paper is a first step towards combining robot dynamics and deep learning. It focuses on using a new method to solve the traditional problem.

Published
2018

48. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Author

Kyu, Hmwe Hmwe, Abate, Degu, Abate, Kalkidan Hassen, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Molla, Abebe, Zegeye, Abil, Olifan Zewdie, Aboyans, Victor, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen M E, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Ackerman, Ilana N, Adamu, Abdu A, Adebayo, Oladimeji M, Adekanmbi, Victor, Ademi, Zanfina, Adetokunboh, Olatunji O, Adib, Mina G, Adsuar, Jose C, Afanvi, Kossivi Agbelenko, Afarideh, Mohsen, Afshin, Ashkan, Agarwal, Gina, Agesa, Kareha M, Aggarwal, Rakesh, Aghayan, Sargis Aghasi, Agrawal, Anurag, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Ahmed, Sayem, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akinyemiju, Tomi, Akseer, Nadia, Al-Aly, Ziyad, Al-Eyadhy, Ayman, Al-Mekhlafi, Hesham M, Al-Raddadi, Rajaa M, Alahdab, Fares, Alam, Khurshid, Alam, Tahiya, Alashi, Alaa, Alavian, Seyed Moayed, Alene, Kefyalew Addis, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Alonso, Jordi, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Aminde, Leopold N, Amini, Erfan, Amiresmaili, Mohammadreza, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla Hamed, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Arabloo, Jalal, Aremu, Olatunde, Ärnlöv, Johan, Arora, Amit, Arora, Megha, Artaman, Al, Aryal, Krishna K, Asayesh, Hamid, Ataro, Zerihun, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide F G A, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Ayer, Rakesh, Azzopardi, Peter S, Babazadeh, Arefeh, Badali, Hamid, Balakrishnan, Kalpana, Bali, Ayele Geleto, Banach, Maciej, Banoub, Joseph Adel Mattar, Barac, Aleksandra, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barquera, Simon, Barrero, Lope H, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Bayu Begashaw, Bekru, Eyasu Tamru, Belachew, Abate Bekele, Belay, Yihalem Abebe, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bensenor, Isabela M, Berhane, Adugnaw, Bernabe, Eduardo, Bernstein, Robert S, Beuran, Mircea, Beyranvand, Tina, Bhala, Neeraj, Bhatt, Samir, Bhaumik, Soumyadeep, Bhutta, Zulfiqar A, Biadgo, Belete, Biehl, Molly H, Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bililign, Nigus, Bin Sayeed, Muhammad Shahdaat, Bisanzio, Donal, Bjørge, Tone, Bleyer, Archie, Bobasa, Eshetu Mulisa, Bou-Orm, Ibrahim R, Boufous, Soufiane, Bourne, Rupert, Brady, Oliver J, Brant, Luisa C, Brayne, Carol, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Briant, Paul Svitil, Briko, Andrey Nikolaevich, Britton, Gabrielle, Brugha, Traolach, Buchbinder, Rachelle, Busse, Reinhard, Butt, Zahid A, Cahuana-Hurtado, Lucero, Campuzano Rincon, Julio Cesar, Cano, Jorge, Cárdenas, Rosario, Carrero, Juan J, Carter, Austin, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Castro, Franz, Catalá-López, Ferrán, Cercy, Kelly M, Cerin, Ester, Chaiah, Yazan, Chang, Jung-Chen, Charlson, Fiona J, Chattu, Vijay Kumar, Chiang, Peggy Pei-Chia, Chitheer, Abdulaal, Choi, Jee-Young J, Christensen, Hanne, Christopher, Devasahayam J, Chung, Sheng-Chia, Cicuttini, Flavia M, Cirillo, Massimo, Collado-Mateo, Daniel, Cooper, Cyrus, Cortesi, Paolo Angelo, Cortinovis, Monica, Cousin, Ewerton, Criqui, Michael H, Cromwell, Elizabeth A, Cross, Marita, Crump, John A, Daba, Alemneh Kabeta, Dachew, Berihun Assefa, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, Daryani, Ahmad, Das Gupta, Rajat, Das Neves, José, Dasa, Tamirat Tesfaye, Davitoiu, Dragos Virgil, De La Hoz, Fernando Pio, De Leo, Diego, De Neve, Jan-Walter, De Steur, Hans, Degefa, Meaza Girma, Degenhardt, Louisa, Deiparine, Selina, Demoz, Gebre Teklemariam, Denova-Gutiérrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Des Jarlais, Don C, Dey, Subhojit, Dharmaratne, Samath D, Dhimal, Meghnath, Dinberu, Mesfin Tadese, Dirac, M Ashworth, Djalalinia, Shirin, Doan, Linh, Dokova, Klara, Doku, David Teye, Dorsey, E Ray, Doyle, Kerrie E, Driscoll, Tim Robert, Dubey, Manisha, Dubljanin, Eleonora, Duken, Eyasu Ejeta, Duncan, Bruce B, Duraes, Andre R, Ebrahimi, Hedyeh, Ebrahimpour, Soheil, Echko, Michelle M, Edessa, Dumessa, Edvardsson, David, Effiong, Andem, Eggen, Anne Elise, Ehrlich, Joshua R, El Bcheraoui, Charbel, El-Khatib, Ziad, Elyazar, Iqbal R F, Enayati, Ahmadali, Endalifer, Melese Linger, Endries, Aman Yesuf, Er, Benjamin, Erskine, Holly E, Eskandarieh, Sharareh, Esteghamati, Alireza, Esteghamati, Sadaf, Fakhim, Hamed, Faramarzi, Mahbobeh, Fareed, Mohammad, Farhadi, Farzaneh, Farid, Talha A, Farinha, Carla Sofia E sá, Farioli, Andrea, Faro, Andre, Farzadfar, Farshad, Fazaeli, Ali Akbar, Feigin, Valery L, Fentahun, Netsanet, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fernandes, Joao C, Ferrari, Alize J, Ferreira, Manuela L, Filip, Irina, Fischer, Florian, Fitzmaurice, Christina, Foigt, Nataliya A, Foreman, Kyle J, Frank, Tahvi D, Fukumoto, Takeshi, Fullman, Nancy, Fürst, Thomas, Furtado, João M, Gakidou, Emmanuela, Gall, Seana, Gallus, Silvano, Ganji, Morsaleh, Garcia-Basteiro, Alberto L, Gardner, William M, Gebre, Abadi Kahsu, Gebremedhin, Amanuel Tesfay, Gebremichael, Teklu Gebrehiwo, Gelano, Tilayie Feto, Geleijnse, Johanna M, Genova-Maleras, Ricard, Geramo, Yilma Chisha Dea, Gething, Peter W, Gezae, Kebede Embaye, Ghadami, Mohammad Rasoul, Ghadiri, Keyghobad, Ghasemi-Kasman, Maryam, Ghimire, Mamata, Ghoshal, Aloke Gopal, Gill, Paramjit Singh, Gill, Tiffany K, Ginawi, Ibrahim Abdelmageed, Giussani, Giorgia, Gnedovskaya, Elena V, Goldberg, Ellen M, Goli, Srinivas, Gómez-Dantés, Hector, Gona, Philimon N, Gopalani, Sameer Vali, Gorman, Taren M, Goulart, Alessandra C, Goulart, Bárbara Niegia Garcia, Grada, Ayman, Grosso, Giuseppe, Gugnani, Harish Chander, Guillemin, Francis, Guo, Yuming, Gupta, Prakash C, Gupta, Rahul, Gupta, Rajeev, Gupta, Tanush, Gutiérrez, Reyna Alma, Gyawali, Bishal, Haagsma, Juanita A, Hachinski, Vladimir, Hafezi-Nejad, Nima, Haghparast Bidgoli, Hassan, Hagos, Tekleberhan B, Hailegiyorgis, Tewodros Tesfa, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hamadeh, Randah R, Hamidi, Samer, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haririan, Hamidreza, Haro, Josep Maria, Hassankhani, Hadi, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hay, Roderick J, Hay, Simon I, Hedayatizadeh-Omran, Akbar, Heibati, Behzad, Hendrie, Delia, Henok, Andualem, Heredia-Pi, Ileana, Herteliu, Claudiu, Heydarpour, Fatemeh, Heydarpour, Pouria, Hibstu, Desalegn Tsegaw, Hoek, Hans W, Hoffman, Howard J, Hole, Michael K, Homaie Rad, Enayatollah, Hoogar, Praveen, Hosgood, H Dean, Hosseini, Seyed Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Htet, Aung Soe, Huang, John J, Iburg, Kim Moesgaard, Ikeda, Chad Thomas, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Irvine, Caleb Mackay Salpeter, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Jacobsen, Kathryn H, Jahangiry, Leila, Jahanmehr, Nader, Jain, Sudhir Kumar, Jakovljevic, Mihajlo, James, Spencer L, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S, Johnson, Catherine O, Jonas, Jost B, Jonnagaddala, Jitendra, Jorjoran Shushtari, Zahra, Joshi, Ankur, Jozwiak, Jacek Jerzy, Jungari, Suresh Banayya, Jürisson, Mikk, Kabir, Zubair, Kadel, Rajendra, Kahsay, Amaha, Kalani, Rizwan, Kanchan, Tanuj, Kar, Chittaranjan, Karami, Manoochehr, Karami Matin, Behzad, Karch, André, Karema, Corine, Karimi, Narges, Karimi, Seyed M, Kasaeian, Amir, Kassa, Dessalegn H, Kassa, Getachew Mullu, Kassa, Tesfaye Dessale, Kassebaum, Nicholas J, Katikireddi, Srinivasa Vittal, Kaul, Anil, Kawakami, Norito, Kazemi, Zhila, Karyani, Ali Kazemi, Keighobadi, Masoud Masoud, Keiyoro, Peter Njenga, Kemmer, Laura, Kemp, Grant Rodgers, Kengne, Andre Pascal, Keren, Andre, Khader, Yousef Saleh, Khafaei, Behzad, Khafaie, Morteza Abdullatif, Khajavi, Alireza, Khalid, Nauman, Khalil, Ibrahim A, Khan, Ejaz Ahmad, Khan, Muhammad Shahzeb, Khan, Muhammad Ali, Khang, Young-Ho, Khater, Mona M, Khazaei, Mohammad, Khoja, Abdullah T, Khosravi, Ardeshir, Khosravi, Mohammad Hossein, Kiadaliri, Aliasghar A, Kidanemariam, Zelalem Teklemariam, Kiirithio, Daniel N, Kim, Cho-Il, Kim, Daniel, Kim, Young-Eun, Kim, Yun Jin, Kimokoti, Ruth W, Kinfu, Yohannes, Kisa, Adnan, Kissimova-Skarbek, Katarzyna, Knudsen, Ann Kristin Skrindo, Kocarnik, Jonathan M, Kochhar, Sonali, Kokubo, Yoshihiro, Kolola, Tufa, Kopec, Jacek A, Kosen, Soewarta, Kotsakis, Georgios A, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Krishnaswami, 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Mohammad, Karzan Abdulmuhsin, Mohammadi, Moslem, Mohammadifard, Noushin, Mohammadnia-Afrouzi, Mousa, Mohammed, Mohammed A, Mohammed, Shafiu, Mohebi, Farnam, Mokdad, Ali H, Molokhia, Mariam, Monasta, Lorenzo, Montañez, Julio Cesar, Moosazadeh, Mahmood, Moradi, Ghobad, Moradi, Mahmoudreza, Moradi-Lakeh, Maziar, Moradinazar, Mehdi, Moraga, Paula, Morawska, Lidia, Moreno Velásquez, Ilais, Morgado-Da-Costa, Joana, Morrison, Shane Douglas, Moschos, Marilita M, Mousavi, Seyyed Meysam, Mruts, Kalayu Brhane, Muche, Achenef Asmamaw, Muchie, Kindie Fentahun, Mueller, Ulrich Otto, Muhammed, Oumer Sada, Mukhopadhyay, Satinath, Muller, Kate, Mumford, John Everett, Murthy, G V S, Musa, Kamarul Imran, Mustafa, Ghulam, Nabhan, Ashraf F, Nagata, Chie, Nagel, Gabriele, Naghavi, Mohsen, Naheed, Aliya, Nahvijou, Azin, Naik, Gurudatta, Najafi, Farid, Nam, Hae Sung, Nangia, Vinay, Nansseu, Jobert Richie, Neamati, Nahid, Negoi, Ionut, Negoi, Ruxandra Irina, Neupane, Subas, Newton, Charles Richard James, Ngunjiri, Josephine W, Nguyen, Anh Quynh, Nguyen, Grant, Nguyen, Ha Thu, Nguyen, Huong Lan Thi, Nguyen, Huong Thanh, Nguyen, Long Hoang, Nguyen, Minh, Nguyen, Nam Ba, Nguyen, Son Hoang, Nichols, Emma, Ningrum, Dina Nur Anggraini, Nixon, Molly R, Nomura, Shuhei, Noroozi, Mehdi, Norrving, Bo, Noubiap, Jean Jacques, Nouri, Hamid Reza, Shiadeh, Malihe Nourollahpour, Nowroozi, Mohammad Reza, Nsoesie, Elaine O, Nyasulu, Peter S, Odell, Christopher M, Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Oh, In-Hwan, Oladimeji, Olanrewaju, Olagunju, Andrew T, Olagunju, Tinuke O, Olivares, Pedro R, Olsen, Helen Elizabeth, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Ong, Kanyin L, Ong, Sok King, Oren, Eyal, Ortiz, Alberto, Ota, Erika, Otstavnov, Stanislav S, Øverland, Simon, Owolabi, Mayowa Ojo, P A, Mahesh, Pacella, Rosana, Pakhare, Abhijit P, Pakpour, Amir H, Pana, Adrian, Panda-Jonas, Songhomitra, Park, Eun-Kee, Park, James, Parry, Charles D H, Parsian, Hadi, Pasdar, Yahya, Patel, 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Shiferaw, Waheed, Yasir, Wang, Yafeng, Wang, Yuan-Pang, Weiderpass, Elisabete, Weintraub, Robert G, Weiss, Daniel J, Weldegebreal, Fitsum, Weldegwergs, Kidu Gidey, Werdecker, Andrea, West, T Eoin, Westerman, Ronny, Whiteford, Harvey A, Widecka, Justyna, Wijeratne, Tissa, Williams, Hywel C, Wilner, Lauren B, Wilson, Shadrach, Winkler, Andrea Sylvia, Wiyeh, Alison B, Wiysonge, Charles Shey, Wolfe, Charles D A, Woolf, Anthony D, Wyper, Grant M A, Xavier, Denis, Xu, Gelin, Yadgir, Simon, Yahyazadeh Jabbari, Seyed Hossein, Yamada, Tomohide, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Yasin, Yasin Jemal, Yeshaneh, Alex, Yimer, Ebrahim M, Yip, Paul, Yisma, Engida, Yonemoto, Naohiro, Yoon, Seok-Jun, Yotebieng, Marcel, Younis, Mustafa Z, Yousefifard, Mahmoud, Yu, Chuanhua, Zadnik, Vesna, Zaidi, Zoubida, Zaman, Sojib Bin, Zamani, Mohammad, Zandian, Hamed, Zar, Heather J, Zenebe, Zerihun Menlkalew, Zhou, Maigeng, Zipkin, Ben, Zodpey, Sanjay, Zucker, Inbar, Zuhlke, Liesl Joanna, and Murray, Christopher J L

Subjects
ddc
Published
2018

49. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Author

Stanaway, Jeffrey D, Afshin, Ashkan, Gakidou, Emmanuela, Lim, Stephen S, Abate, Degu, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Molla, Abebe, Zegeye, Abera, Semaw F, Abil, Olifan Zewdie, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen ME, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Adamu, Abdu A, Adane, Akilew Awoke, Adebayo, Oladimeji M, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Ademi, Zanfina, Adetokunboh, Olatunji O, Adib, Mina G, Admasie, Amha, Adsuar, Jose C, Afanvi, Kossivi Agbelenko, Afarideh, Mohsen, Agarwal, Gina, Aggarwal, Anju, Aghayan, Sargis Aghasi, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akbari, Mohammad Esmaeil, Akinyemiju, Tomi, Akseer, Nadia, Al-Aly, Ziyad, Al-Eyadhy, Ayman, Al-Mekhlafi, Hesham M, Alahdab, Fares, Alam, Khurshid, Alam, Samiah, Alam, Tahiya, Alashi, Alaa, Alavian, Seyed Moayed, Alene, Kefyalew Addis, Ali, Komal, Ali, Syed Mustafa, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Ammar, Walid, Anber, Nahla Hamed, Anderson, Jason A, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansha, Mustafa Geleto, Antó, Josep M, Antonio, Carl Abelardo T, Anwari, Palwasha, Appiah, Lambert Tetteh, Appiah, Seth Christopher Yaw, Arabloo, Jalal, Aremu, Olatunde, Ärnlöv, Johan, Artaman, Al, Aryal, Krishna K, Asayesh, Hamid, Ataro, Zerihun, Ausloos, Marcel, Avokpaho, Euripide F G A, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Ayer, Rakesh, Ayuk, Tambe B, Azzopardi, Peter S, Babazadeh, Arefeh, Badali, Hamid, Badawi, Alaa, Balakrishnan, Kalpana, Bali, Ayele Geleto, Ball, Kylie, Ballew, Shoshana H, Banach, Maciej, Banoub, Joseph Adel Mattar, Barac, Aleksandra, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barrero, Lope H, Basu, Sanjay, Baune, Bernhard T, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Béjot, Yannick, Bekele, Bayu Begashaw, Bekru, Eyasu Tamru, Belay, Ezra, Belay, Yihalem Abebe, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bensenor, Isabela M, Bergeron, Gilles, Berhane, Adugnaw, Bernabe, Eduardo, Bernstein, Robert S, Beuran, Mircea, Beyranvand, Tina, Bhala, Neeraj, Bhalla, Ashish, Bhattarai, Suraj, Bhutta, Zulfiqar A, Biadgo, Belete, Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bililign, Nigus, Bin Sayeed, Muhammad Shahdaat, Bisanzio, Donal, Biswas, Tuhin, Bjørge, Tone, Blacker, Brigette F, Bleyer, Archie, Borschmann, Rohan, Bou-Orm, Ibrahim R, Boufous, Soufiane, Bourne, Rupert, Brady, Oliver J, Brauer, Michael, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Briko, Andrey Nikolaevich, Britton, Gabrielle, Brugha, Traolach, Buchbinder, Rachelle, Burnett, Richard T, Busse, Reinhard, Butt, Zahid A, Cahill, Leah E, Cahuana-Hurtado, Lucero, Campos-Nonato, Ismael R, Cárdenas, Rosario, Carreras, Giulia, Carrero, Juan J, Carvalho, Félix, Castañeda-Orjuela, Carlos A, Castillo Rivas, Jacqueline, Castro, Franz, Catalá-López, Ferrán, Causey, Kate, Cercy, Kelly M, Cerin, Ester, Chaiah, Yazan, Chang, Hsing-Yi, Chang, Jung-Chen, Chang, Kai-Lan, Charlson, Fiona J, Chattopadhyay, Aparajita, Chattu, Vijay Kumar, Chee, Miao Li, Cheng, Ching-Yu, Chew, Adrienne, Chiang, Peggy Pei-Chia, Chimed-Ochir, Odgerel, Chin, Ken Lee, Chitheer, Abdulaal, Choi, Jee-Young J, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam J, Chung, Sheng-Chia, Cicuttini, Flavia M, Cirillo, Massimo, Cohen, Aaron J, Collado-Mateo, Daniel, Cooper, Cyrus, Cooper, Owen R, Coresh, Josef, Cornaby, Leslie, Cortesi, Paolo Angelo, Cortinovis, Monica, Costa, Megan, Cousin, Ewerton, Criqui, Michael H, Cromwell, Elizabeth A, Cundiff, David K, Daba, Alemneh Kabeta, Dachew, Berihun Assefa, Dadi, Abel Fekadu, Damasceno, Albertino Antonio Moura, Dandona, Lalit, Dandona, Rakhi, Darby, Sarah C, Dargan, Paul I, Daryani, Ahmad, Das Gupta, Rajat, Das Neves, José, Dasa, Tamirat Tesfaye, Dash, Aditya Prasad, Davitoiu, Dragos Virgil, Davletov, Kairat, De la Cruz-Góngora, Vanessa, De La Hoz, Fernando Pio, De Leo, Diego, De Neve, Jan-Walter, Degenhardt, Louisa, Deiparine, Selina, Dellavalle, Robert P, Demoz, Gebre Teklemariam, Denova-Gutiérrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Deshpande, Aniruddha, Des Jarlais, Don C, Dessie, Getenet Ayalew, Deveber, Gabrielle Aline, Dey, Subhojit, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dinberu, Mesfin Tadese, Ding, Eric L, Diro, Helen Derara, Djalalinia, Shirin, Do, Huyen Phuc, Dokova, Klara, Doku, David Teye, Doyle, Kerrie E, Driscoll, Tim R, Dubey, Manisha, Dubljanin, Eleonora, Duken, Eyasu Ejeta, Duncan, Bruce B, Duraes, Andre R, Ebert, Natalie, Ebrahimi, Hedyeh, Ebrahimpour, Soheil, Edvardsson, David, Effiong, Andem, Eggen, Anne Elise, El Bcheraoui, Charbel, El-Khatib, Ziad, Elyazar, Iqbal Rf, Enayati, Ahmadali, Endries, Aman Yesuf, Er, Benjamin, Erskine, Holly E, Eskandarieh, Sharareh, Esteghamati, Alireza, Estep, Kara, Fakhim, Hamed, Faramarzi, Mahbobeh, Fareed, Mohammad, Farid, Talha A, Farinha, Carla Sofia E sá, Farioli, Andrea, Faro, Andre, Farvid, Maryam S, Farzaei, Mohammad Hosein, Fatima, Batool, Fay, Kairsten A, Fazaeli, Ali Akbar, Feigin, Valery L, Feigl, Andrea B, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fernandes, Joao C, Ferrara, Giannina, Ferrari, Alize J, Ferreira, Manuela L, Filip, Irina, Finger, Jonas David, Fischer, Florian, Foigt, Nataliya A, Foreman, Kyle J, Fukumoto, Takeshi, Fullman, Nancy, Fürst, Thomas, Furtado, João M, Futran, Neal D, Gall, Seana, Gallus, Silvano, Gamkrelidze, Amiran, Ganji, Morsaleh, 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Luis, Zhang, Anthony Lin, Zhang, Hao, Zhang, Kai, Zhou, Maigeng, Zimsen, Stephanie R M, Zodpey, Sanjay, and Murray, Christopher J L

Subjects
ddc
Published
2018

50. Additional file 1: of Intrafollicular fibroblast growth factor 13 in polycystic ovary syndrome: relationship with androgen levels and oocyte developmental competence

Author

Liu, Yu, Shengxian Li, Tao, Tao, Xiaoxue Li, Qinling Zhu, Liao, Yu, Ma, Jing, Sun, Yun, and Liu, Wei

Subjects
endocrine system diseases, nutritional and metabolic diseases, female genital diseases and pregnancy complications
Abstract

Correlations between FF-FGF21 and oocyte development competence in PCOS patients. (DOCX 14Â kb)

Published
2018
Full Text
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