1. Safety evaluation of early drain removal following pancreaticoduodenectomy: A single-center retrospective cohort study
- Author
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Xie, Xuehai, Chen, Kai, Liu, Zonghao, Wang, Feng, Ma, Yongsu, Zhang, Shupeng, Shao, Zhijiang, Yang, Yinmo, and Tian, Xiaodong
- Subjects
Cancer Research ,Oncology - Abstract
ObjectivesThe effects of early drain removal (EDR) on postoperative complications after pancreaticoduodenectomy (PD) remains to be investigated. This single-center retrospective cohort study was designed to explore the safety of EDR after PD.MethodsA total of 112 patients undergoing PD with drain fluid amylase (DFA) on postoperative day (POD) 1 and 3 ResultsNo statistical differences were found in primary outcomes, including Grade B/C postoperative pancreatic fistula (POPF) (Original cohort: 5.71% vs. 3.90%; P = 1.000; PSM cohort: 3.33% vs. 6.67%; P = 1.000), and total complications (Original cohort: 17.14% vs. 32.47%; P = 0.093; PSM cohort: 13.33% vs. 33.33%; P = 0.067). The EDR was associated with shorter in-hospital stay (Original cohort: 11 days vs. 15 days; P < 0.0001; PSM cohort: 11 days vs. 15 days; P < 0.0001).ConclusionsEDR on POD 3 is safe for patients undergoing PD with low risk of POPF.
- Published
- 2022