1. Variations in cervico-vaginal microbiota among HPV-positive and HPV-negative asymptomatic women in Peru
- Author
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Isaac Peña-Tuesta, Miguel Angel Aguilar-Luis, Luis Pinillos-Vilca, Ronald Aquino-Ortega, Juana del Valle-Mendoza, Carmen Tinco-Valdez, Johanna Martins-Luna, Yordi Tarazona-Castro, Wilmer Silva-Caso, Hugo Carrillo-Ng, Lorena Becerra-Goicochea, Luis J. del Valle, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables., and Universitat Politècnica de Catalunya. PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables
- Subjects
Human papillomavirus ,HPV ,cervical cancer ,lcsh:Medicine ,Uterine Cervical Neoplasms ,Cervix Uteri ,Asymptomatic ,General Biochemistry, Genetics and Molecular Biology ,Actinobacteria ,Microbiology ,fluids and secretions ,Peru ,medicine ,microbiota ,Humans ,Eubacterium ,lcsh:Science (General) ,human papillomavirus ,Càncer ,lcsh:QH301-705.5 ,Papillomaviridae ,Bifidobacterium ,Cervical cancer ,biology ,Microbiota ,lcsh:R ,Papillomavirus Infections ,Enginyeria biomèdica [Àrees temàtiques de la UPC] ,General Medicine ,biology.organism_classification ,medicine.disease ,female genital diseases and pregnancy complications ,Research Note ,PCR ,Fusobacterium ,Enterococcus ,lcsh:Biology (General) ,Female ,Bacteroides ,medicine.symptom ,lcsh:Q1-390 ,Ciències de la salut [Àrees temàtiques de la UPC] - Abstract
Objective To characterize the cervicovaginal microbiota of HPV-positive and HPV-negative asymptomatic Peruvian women, by identifying the presence of 13 representative bacteria genus. Results A total of 100 HPV-positive and 100 HPV-negative women were matched by age for comparison of microbiota. The following bacteria were more frequently identified in HPV-positive patients compared to HPV-negative: Eubacterium (68 vs 32%), Actinobacteria (46 vs 33%), Fusobacterium (11 vs 6%) and Bacteroides (20 vs 13%). A comparison between high-risk and low-risk genotypes was performed and differences were found in the detection of Actinobacteria (50 vs 33.33%), Bifidobacterium (50 vs 20.83%) and Enterococcus (50 vs 29.17%).
- Published
- 2021