1. Cloning of Z39Ig, a novel gene with immunoglobulin-like domains located on human chromosome X
- Author
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Kristina Langnaese, Laurence Colleaux, Peter Wieacker, Michel Fontes, Dorothee U Kloos, Département de génétique médicale [Hôpital de la Timone - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Institut National de la Santé et de la Recherche Médicale (INSERM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)
- Subjects
MESH: Immunoglobulins ,DNA, Complementary ,X Chromosome ,Molecular Sequence Data ,Biophysics ,Immunoglobulins ,MESH: Amino Acid Sequence ,MESH: Base Sequence ,Biology ,Biochemistry ,Structural Biology ,Complementary DNA ,Genetics ,Humans ,MESH: Cloning, Molecular ,Tissue Distribution ,Amino Acid Sequence ,MESH: Tissue Distribution ,Cloning, Molecular ,Gene ,Peptide sequence ,X chromosome ,Cloning ,Messenger RNA ,MESH: X Chromosome ,MESH: Humans ,MESH: Molecular Sequence Data ,Base Sequence ,Chromosome Mapping ,MESH: DNA, Complementary ,TCF4 ,Molecular biology ,Receptors, Complement ,MESH: Receptors, Complement ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Immunoglobulin superfamily ,MESH: Chromosome Mapping - Abstract
International audience; The cDNA sequence and expression profile of a novel human gene, encoding a new member of the immunoglobulin superfamily, is reported. The gene is localized in the pericentromeric region of human X chromosome between the markers DXS1213 and DXS1194. Abundant expression of transcripts was detected in several human fetal tissues, whereas among adult tissues lung and placenta express highest levels of Z39Ig mRNA.
- Published
- 2000