1. Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study)
- Author
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Serge Briançon, Stéphanie Boini, L. Frimat, Michèle Kessler, Nathalie Thilly, Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Nancy, Cancéropôle du Grand Est-Institut National de la Santé et de la Recherche Médicale (INSERM), Maladies chroniques, santé perçue, et processus d'adaptation (APEMAC), Université Paris Descartes - Paris 5 (UPD5)-Université de Lorraine (UL), Service de Néphrologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), The AVENIR study was supported by a grant from the Hospital Program of Clinical Research (PHRC 2004) of the French Ministry of Health., BMC, Ed., Cancéropôle du Grand Est-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Maladies chroniques, santé perçue, et processus d'adaptation ( APEMAC ), Université Paris Descartes - Paris 5 ( UPD5 ) -Université de Lorraine ( UL ), and Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy )
- Subjects
Male ,Nephrology ,MESH: Observation ,Health Status ,medicine.medical_treatment ,MESH : Aged ,MESH : Nephrology ,030232 urology & nephrology ,Observation ,MESH : Observation ,Cohort Studies ,0302 clinical medicine ,Cost of Illness ,Surveys and Questionnaires ,MESH : Cost of Illness ,MESH : Female ,MESH: Renal Dialysis ,030212 general & internal medicine ,Disease management (health) ,MESH: Cohort Studies ,MESH: Health Status ,MESH: Aged ,MESH: Middle Aged ,MESH : Questionnaires ,Disease Management ,[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie ,MESH: Nephrology ,General Medicine ,MESH : Adult ,Middle Aged ,MESH: Cost of Illness ,MESH : Renal Dialysis ,humanities ,3. Good health ,MESH: Kidney Failure, Chronic ,lcsh:R858-859.7 ,Female ,Cohort study ,Adult ,medicine.medical_specialty ,MESH : Male ,MESH: Renal Insufficiency, Chronic ,MEDLINE ,MESH : Cohort Studies ,MESH : Renal Insufficiency, Chronic ,lcsh:Computer applications to medicine. Medical informatics ,MESH: Disease Management ,MESH : Kidney Failure, Chronic ,MESH: Multivariate Analysis ,03 medical and health sciences ,Quality of life (healthcare) ,Renal Dialysis ,Internal medicine ,medicine ,Humans ,MESH : Middle Aged ,Renal replacement therapy ,MESH : Health Status ,Renal Insufficiency, Chronic ,Intensive care medicine ,Dialysis ,Aged ,Health related quality of life ,MESH: Humans ,business.industry ,Research ,MESH: Questionnaires ,MESH : Humans ,Public Health, Environmental and Occupational Health ,MESH : Multivariate Analysis ,MESH: Quality of Life ,MESH: Adult ,MESH : Quality of Life ,MESH : Disease Management ,MESH: Male ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Multivariate Analysis ,Quality of Life ,Kidney Failure, Chronic ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,business ,MESH: Female - Abstract
Background To determine the impact of the quality of pre-dialysis nephrological care on health-related quality of life (HRQoL) at dialysis onset, which has not been well evaluated. Methods All adults who began a dialysis treatment in the administrative region of Lorraine (France) in 2005 or 2006, were enrolled in this prospective observational study. HRQoL was measured using the Kidney Disease Quality of Life V36 questionnaire, which enables calculation of two generic (physical and mental) and three specific dimensions (Symptoms/problems, Effects and Burden of kidney disease). The specific dimensions were scored from 0 to 100 (worst to best possible functioning). Pre-dialysis nephrological care was measured using three indicators: quality of therapeutic practices (evaluated across five main aspects: hypertension/proteinuria, anemia, bone disease, metabolic acidosis and dyslipidemia), time since referral to a nephrologist and number of nephrology consultations in the year preceding dialysis treatment. Results Two thousand and eighty-three (67.4%) patients were referred to a nephrologist more than 1 month before dialysis initiation and completed the HRQoL questionnaire. Quality of therapeutic practices was significantly associated with the Mental component. Time since referral to a nephrologist was associated with Symptoms/problems and the Effects of kidney disease dimensions, but no relationship was found between the number of nephrology consultations and HRQoL. Conclusions HRQoL at dialysis onset is significantly influenced by the quality of pre-dialysis nephrological care. Therefore, disease management should be emphasized.
- Published
- 2011
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