1. 282 Follow-up of hospitalized COVID-19 survivors: assessment of short- and long-term cardiovascular sequelae after SARS-CoV-2 infection
- Author
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Birtolo, Lucia Ilaria, Prosperi, Silvia, Monosilio, Sara, Cimino, Sara, Filomena, Domenico, Alfarano, Maria, Manzi, Giovanna, Neccia, Matteo, Papa, Silvia, Passarelli, Ilaria, De Persis, Francesca, Luca, Alessandra De, Mei, Mariachiara, Di Iorio, Martina, D’Antoni, Letizia, Di Pietro, Gianluca, Francavilla, Santi, Improta, Riccardo, Marcon, Serena, Mariani, Marco Valerio, Agnes, Gianluca, Piro, Agostino, Rizzo, Massimiliano, Rachele, Edoardo Sebastian, Straito, Martina, Tocci, Marco, Francone, Marco, Galea, Nicola, Severino, Paolo, Pasculli, Patrizia, Colaiacomo, Maria Chiara, Petroianni, Angelo, Chimenti, Cristina, Lavalle, Carlo, Badagliacca, Roberto, Palange, Paolo, Mastroianni, Claudio, Catalano, Carlo, Pugliese, Francesco, Ciardi, Maria, Maestrini, Viviana, Mancone, Massimo, and Fedele, Francesco
- Subjects
AcademicSubjects/MED00200 ,Covid-19 ,Cardiology and Cardiovascular Medicine - Abstract
Aims Cardiovascular sequelae in COVID-19 survivors remain largely unclear and can potentially go unrecognized. Reports on follow-up focused on cardiovascular evaluation after hospital discharge are currently scarce. Aim of this prospective study was to assess cardiovascular sequelae in previously hospitalized COVID-19 survivors. Methods and results The study was conducted at ‘Sapienza’ University of Rome—Policlinico ‘Umberto I’. After 2 months from discharge, n = 230 COVID-19 survivors underwent a follow-up visit at a dedicated ‘post-COVID Outpatient Clinic’. A cardiovascular evaluation including electrocardiogram (ECG), Troponin and echocardiography was performed. Further tests were requested when clinically indicated. Medical history, symptoms, arterial-blood gas, blood tests, chest computed tomography, and treatment of both in-hospital and follow-up evaluation were recorded. A 1-year telephone follow-up was performed. A total of 36 (16%) COVID-19 survivors showed persistence or delayed onset of cardiovascular disease at 2-months follow-up visit. Persistent condition was recorded in 62% of survivors who experienced an in-hospital cardiovascular disease. Delayed cardiovascular involvement included: myocarditis, pericarditis, ventricular disfunction, new onset of systemic hypertension and arrhythmias. At 1-year telephone follow-up, 105 (45%) survivors reported persistent symptoms, with dyspnoea and fatigue being the most frequent. 60% of survivors showed persistent chest CT abnormalities and among those 28% complained of persistent cardiopulmonary symptoms at long term follow-up. Conclusions Our preliminary data showed persistent or delayed onset of cardiovascular involvement (16%) at short-term follow-up and persistent symptoms (45%) at long-term follow-up. These findings suggest the need for monitoring COVID-19 survivors.
- Published
- 2021