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Objectives: Tension-free vaginal tapes are the gold standard of the surgical treatment of stress urinary incontinence (SUI); however, long-term recurrence of SUI after this surgery has been a matter of problem. Here, we attempted to determine the incidence of its recurrence and to identify the risk factors of 4-year-recurrence of SUI after this surgery. Methods: Of all patients undergoing this surgery (n = 341, 2015-2019), 71 patients were met the study inclusion criteria. Of 71, SUI recurred in 8 patients, with the recurrence rate being 11.3%. The following three were identified to be independent risk factors: older age, history of delivery of macrosomic baby (>4 kg), and the presence of mixed urinary incontinence. The frequency of recurrence in cases with mixed incontinence amounted for 19.5%. Recurrence was 22 and 50% for women with macrosomic delivery once and more than twice, respectively. Conclusion: Advanced age, macrosomic delivery and mixed urinary incontinence have shown to be independent risk factors of recurrence of SUI after tension-free vaginal tape-obturator at 4 years. Key message: Stress urinary incontinence can recur so investigate possible risk factors is a priority. Our paper relates recurrence with: advanced age, fetal macrosomia and mixed incontinence.

Introduction and hypothesis: Stress urinary incontinence (SUI) affects 5-35% of women, especially at menopause. In severe cases or when conservative treatment fails, a tensión-free suburethral band is indicated. Similar short-medium term cure rates have been reported with mini-sling (SIS) compared to retropubic and transobturator band. But the long-term information is scarce and it seems that the risk of recurrence is not negligible (4-37%). There is little literatura that studies the posible predisposing factors for the recurrence of SUI after SIS. The objective is to identify factors associated with the risk of relapse of SUI at 5 years, after SIS. Methods: A prospective five-years follow-up observational study (2015-2019) was performed in women who underwent SUI using SIS. The sample was 115 patients with relapse of SUI. Statistics: T-Student or U-Mann and ROC for quantitative variables, Chi-Squared and OR for qualitative variables. Results: L25 patients (21.74%) had recurrence during the study period. Of all the variables analyzed, they only showed a significant association with the recurrence of SUI: height, weigth and BMI, a history of fetal macrosomia and the number of compresses used. The patients who presented recurrence of SUI had a lower heigth, greater weight, and therefore a higher BMI. The obstetrics history of a vaginal delivery with a fetus >4 kg, was associated with a higher risk of recurrence (OR: 4.05, IC 95%=1.09-15.03), and the use of a greater number of compresses was also associated with an increased risk of relapse, obtaining an area under the curve of 0.659. Conclusion: The 5-year recurrence rateo f SUI after mini-sling in our setting was 21.74%. A lower height, a greater weight and BMI, macrosomic delivery and greater number of purses have shown a significant association with the risk of relapse of SUI after mini-sling at 5 years. Therefore, it is essential to adecuately advise patients according to their personal factors of the potencial risk of recurrence after SIS.

Salmonella enterica is a microorganism with high zoonotic potential, distributed worldwide, having more than 2,610 identified serovars and affecting different animal species, both production and wildlife animals. Objective: Prevention of human salmonellosis requires prior monitoring of Salmonella in animals. In this study. Salmonella enterica serovars from different animal origins were isolated and their antimicrobial susceptibility was determined. Methods: A total of 2193 samples from different origins (feces of cattle, sheep, horses, pigs, dog, chickens and seagulls and chicken eggs) were analyzed for bacterial typing and antimicrobial susceptibility was studied by the Kirby-Bauer method including 9 antibacterial agents (florfenicol, amoxicillin, ceftiofur, gentamicin, oxytetracycline, trimethoprim/sulfamethoxazole, enrofloxacine, ampicillin and cefoperazone) and MIC50 and MIC90 for 6 of them were determined. Results: A 4.38% serovar isolation (n = 96), including 6 S. Typhimurium (6.25%) from equine cattle and pig feces, 19 S. Enteritidis (19.79%) from seagulls and pigs and 71 other serovars, was obtained from the various animal origins. Serovar S. Typhimurium showed high resistance to oxytetracycline and gentamicin by the Kirby-Bauer method and a MIC90 of 512 μg.mL-1 for oxytetracycline and trimethoprim/sulfamethoxazole antibiotics. By the diffusion method, serovar S. Enteritidis was resistant to trimethoprim/sulfamethoxazole and its MIC90 was 256 μg.mL-1 for oxytetracycline. The 32% of Salmonella isolates showed multi-resistance, 2 strains, isolated from pigs (one S. Typhimurium and one S. Enteritidis serovars), showed resistance to 5 antimicrobials tested. Conclusion: The constant release of these serovars to the environment, reaching also animal food, is a permanent potential risk for public health, turning into a first priority the establishment of control and antibiotic therapy strategies.