1. Oral and dental health status in patients with primary antibody deficiencies
- Author
-
Meighani, Ghasem, Aghamohammadi, Asghar, Javanhakht, Honarmand, Abolhassani, Hassan, Sina Nikayin, Jafari, Seyed Mehryar, Motlagh, Mehdi Ghandehari, Shamshiri, Ahmad Reza, and Rezaei, Nima
- Subjects
Male ,Adolescent ,X-linked agamaglubulinemia ,Oral manifestation ,Health Status ,lcsh:R ,Immunologic Deficiency Syndromes ,lcsh:Medicine ,Oral Health ,Aphthous ,Common variable immunodeficiency ,stomatognathic diseases ,Dental carries ,stomatognathic system ,Tooth Diseases ,Immunoglobulin ,Humans ,Female ,Child ,Mouth Diseases - Abstract
Primary antibody deficiencies (PAD) are a group of immune system disorders, associated with decreased levels of secretory and protective immunoglobulins. Because of the important role of immunoglobulins in the protection of oral cavity, patients with PADs are more susceptible to dental caries or oral manifestations. This study was performed to investigate the oral and dental manifestations of PADs patients. In this study, 33 patients with PADs (21 common variable immunodeficiency, 8 X- linked agammaglobulinemia and 4 hyper IgM syndrome) and 66 controls were examined; the number of decayed, missed and filled teeth (DMFT) were investigated. Aphthous was the most frequent manifestation in PADs patients (38.7%), which wassignificantly16.7% higher than the controls (p=0.03). The patients with PADs showed significantly higher presentation of other oral and dental manifestations, including herpes sores, candidiasis tonsillitis, gingivitis, calculus, enamel hypoplasia and other ulcerations. The mean DMFT scores were 6.15±3.6 and 1.93±0.4 in PADs patients and controls, respectively (p
- Published
- 2011