1. Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study
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Arouca, Aline B., Santaliestra-Pasías, Alba M., Moreno, Luis A., Marcos, Ascensión, Widhalm, Kurt, Molnár, Dénes, Manios, Yannis, Gottrand, Frederic, Kafatos, Anthony, Kersting, Mathilde, Sjöström, Michael, Sáinz, Ángel Gutiérrez, Ferrari, Marika, Huybrechts, Inge, González-Gross, Marcela, Forsner, Maria, de Henauw, Stefaan, Michels, Nathalie, Gottrand, Fréderic, Gilbert, Chantal, Libersa, Christian, Castelló, Sara, Sjöstrom, Michael, Dallongeville, Jean, Hall, Gunnar, Maes, Lea, Scalfi, Luca, Meléndez, Pilar, Casajús, José A., Fleta, Jesús, Rodríguez, Gerardo, Tomás, Concepción, Mesana, María I., Vicente-Rodríguez, Germán, Villarroya, Adoración, Gil, Carlos M., Ara, Ignacio, Alvira, Juan Fernández, Bueno, Gloria, Bueno, Olga, León, Juan F., Garagorri, Jesús Mª, Labayen, Idoia, Bel, Silvia, Gracia Marco, Luis A., Mouratidou, Theodora, Santaliestra-Pasías, Alba, Iglesia, Iris, González-Gil, Esther, de Miguel-Etayo, Pilar, Julián, Cristina, Miguel-Berges, Mary, Iguacel, Isabel, Rupérez, Azahara, Wärnberg, Julia, Nova, Esther, Gómez, Sonia, Díaz, Ligia Esperanza, Romeo, Javier, Veses, Ana, Zapatera, Belén, Pozo, Tamara, Martínez, David, Beghin, Laurent, Gottrand, Frédéric, Iliescu, Catalina, von Berlepsch, Juliana, Sichert-Hellert, Wolfgang, Koeppen, Ellen, Erhardt, Eva, Csernus, Katalin, Török, Katalin, Bokor, Szilvia, Angster, null, Nagy, Enikö, Kovács, Orsolya, Répasi, Judit, Codrington, Caroline, Plada, María, Papadaki, Angeliki, Sarri, Katerina, Viskadourou, Anna, Hatzis, Christos, Kiriakakis, Michael, Tsibinos, George, Vardavas, Constantine, Sbokos, Manolis, Protoyeraki, Eva, Fasoulaki, Maria, Stehle, Peter, Pietrzik, Klaus, Breidenassel, Christina, Spinneker, Andre, Al-Tahan, Jasmin, Segoviano, Miriam, Berchtold, Anke, Bierschbach, Christine, Blatzheim, Erika, Schuch, Adelheid, Pickert, Petra, Castillo, Manuel J., Gutiérrez, Ángel, Ortega, Francisco B, Ruiz, Jonatan R, Artero, Enrique G, España, Vanesa, Jiménez-Pavón, David, Chillón, Palma, Sánchez-Muñoz, Cristóbal, Cuenca, Magdalena, Arcella, Davide, Azzini, Elena, Barrison, Emma, Bevilacqua, Noemi, Buonocore, Pasquale, Catasta, Giovina, Censi, Laura, Ciarapica, Donatella, D’Acapito, Paola, Galfo, Myriam, Le Donne, Cinzia, Leclercq, Catherine, Maiani, Giuseppe, Mauro, Beatrice, Mistura, Lorenza, Pasquali, Antonella, Piccinelli, Raffaela, Polito, Angela, Roccaldo, Romana, Spada, Raffaella, Sette, Stefania, Zaccaria, Maria, Vitaglione, Paola, Montagnese, Concetta, de Bourdeaudhuij, Ilse, de Vriendt, Tineke, Matthys, Christophe, Vereecken, Carine, de Maeyer, Mieke, Ottevaere, Charlene, Phillipp, Katharina, Dietrich, Sabine, Boriss-Riedl, Birgit Kubelka Marion, Grammatikaki, Eva, Bouloubasi, Zoi, Cook, Tina Louisa, Eleutheriou, Sofia, Consta, Orsalia, Moschonis, George, Katsaroli, Ioanna, Kraniou, George, Papoutsou, Stalo, Keke, Despoina, Petraki, Ioanna, Bellou, Elena, Tanagra, Sofia, Kallianoti, Kostalenia, Argyropoulou, Dionysia, Tsikrika, Stamatoula, Karaiskos, Christos, Meirhaeghe, Aline, Hagströmer, María, Wennlöf, Anita Hurtig, Hallström, Lena, Patterson, Emma, Kwak, Lydia, Rizzo, Nico, Sánchez-Molero, Jackie, Picó, Elena, Navarro, Maite, Viadel, Blanca, Carreres, José Enrique, Merino, Gema, Sanjuán, Rosa, Lorente, María, Sánchez, María José, Thomas, Sarah, Allchurch, Elaine, Burgess, Peter, Astrom, Annika, Sverkén, Anna, Broberg, Agneta, Masson, Annick, Lehoux, Claire, Brabant, Pascal, Pate, Philippe, Fontaine, Laurence, Sebok, Andras, Kuti, Tunde, Hegyi, Adrienn, Maldonado, Cristina, Llorente, Ana, García, Emilio, von Fircks, Holger, Hallberg, Marianne Lilja, Messerer, Maria, Larsson, Mats, Fredriksson, Helena, Adamsson, Viola, Börjesson, Ingmar, Fernández, Laura, Smillie, Laura, Wills, Josephine, Pedrero-Chamizo, Raquel, Meléndez, Agustín, Valtueña, Jara, Albers, Ulrike, Benito, Pedro J., Lorente, Juan José Gómez, Cañada, David, Urzanqui, Alejandro, Torres, Rosa María, Navarro, Paloma, Arouca, Aline B., Santaliestra-Pasías, Alba M., Moreno, Luis A., Marcos, Ascensión, Widhalm, Kurt, Molnár, Déne, Manios, Yanni, Gottrand, Frederic, Kafatos, Anthony, Kersting, Mathilde, Sjöström, Michael, Sáinz, Ángel Gutiérrez, Ferrari, Marika, Huybrechts, Inge, González-Gross, Marcela, Forsner, Maria, de Henauw, Stefaan, Michels, Nathalie, Gottrand, Fréderic, Gilbert, Chantal, Libersa, Christian, Castelló, Sara, Sjöstrom, Michael, Dallongeville, Jean, Hall, Gunnar, Maes, Lea, Scalfi, Luca, Meléndez, Pilar, Casajús, José A., Fleta, Jesú, Rodríguez, Gerardo, Tomás, Concepción, Mesana, María I., Vicente-Rodríguez, Germán, Villarroya, Adoración, Gil, Carlos M., Ara, Ignacio, Alvira, Juan Fernández, Bueno, Gloria, Bueno, Olga, León, Juan F., Garagorri, Jesús Mª, Labayen, Idoia, Bel, Silvia, Gracia Marco, Luis A., Mouratidou, Theodora, Santaliestra-Pasías, Alba, Iglesia, Iri, González-Gil, Esther, de Miguel-Etayo, Pilar, Julián, Cristina, Miguel-Berges, Mary, Iguacel, Isabel, Rupérez, Azahara, Wärnberg, Julia, Nova, Esther, Gómez, Sonia, Díaz, Ligia Esperanza, Romeo, Javier, Veses, Ana, Zapatera, Belén, Pozo, Tamara, Martínez, David, Beghin, Laurent, Gottrand, Frédéric, Iliescu, Catalina, von Berlepsch, Juliana, Sichert-Hellert, Wolfgang, Koeppen, Ellen, Erhardt, Eva, Csernus, Katalin, Török, Katalin, Bokor, Szilvia, Angster, Null, Nagy, Enikö, Kovács, Orsolya, Répasi, Judit, Codrington, Caroline, Plada, María, Papadaki, Angeliki, Sarri, Katerina, Viskadourou, Anna, Hatzis, Christo, Kiriakakis, Michael, Tsibinos, George, Vardavas, Constantine, Sbokos, Manoli, Protoyeraki, Eva, Fasoulaki, Maria, Stehle, Peter, Pietrzik, Klau, Breidenassel, Christina, Spinneker, Andre, Al-Tahan, Jasmin, Segoviano, Miriam, Berchtold, Anke, Bierschbach, Christine, Blatzheim, Erika, Schuch, Adelheid, Pickert, Petra, Castillo, Manuel J., Gutiérrez, Ángel, Ortega, Francisco B, Ruiz, Jonatan R, Artero, Enrique G, España, Vanesa, Jiménez-Pavón, David, Chillón, Palma, Sánchez-Muñoz, Cristóbal, Cuenca, Magdalena, Arcella, Davide, Azzini, Elena, Barrison, Emma, Bevilacqua, Noemi, Buonocore, Pasquale, Catasta, Giovina, Censi, Laura, Ciarapica, Donatella, D’Acapito, Paola, Galfo, Myriam, Le Donne, Cinzia, Leclercq, Catherine, Maiani, Giuseppe, Mauro, Beatrice, Mistura, Lorenza, Pasquali, Antonella, Piccinelli, Raffaela, Polito, Angela, Roccaldo, Romana, Spada, Raffaella, Sette, Stefania, Zaccaria, Maria, Vitaglione, Paola, Montagnese, Concetta, de Bourdeaudhuij, Ilse, de Vriendt, Tineke, Matthys, Christophe, Vereecken, Carine, de Maeyer, Mieke, Ottevaere, Charlene, Phillipp, Katharina, Dietrich, Sabine, Boriss-Riedl, Birgit Kubelka Marion, Grammatikaki, Eva, Bouloubasi, Zoi, Cook, Tina Louisa, Eleutheriou, Sofia, Consta, Orsalia, Moschonis, George, Katsaroli, Ioanna, Kraniou, George, Papoutsou, Stalo, Keke, Despoina, Petraki, Ioanna, Bellou, Elena, Tanagra, Sofia, Kallianoti, Kostalenia, Argyropoulou, Dionysia, Tsikrika, Stamatoula, Karaiskos, Christo, Meirhaeghe, Aline, Hagströmer, María, Wennlöf, Anita Hurtig, Hallström, Lena, Patterson, Emma, Kwak, Lydia, Rizzo, Nico, Sánchez-Molero, Jackie, Picó, Elena, Navarro, Maite, Viadel, Blanca, Carreres, José Enrique, Merino, Gema, Sanjuán, Rosa, Lorente, María, Sánchez, María José, Thomas, Sarah, Allchurch, Elaine, Burgess, Peter, Astrom, Annika, Sverkén, Anna, Broberg, Agneta, Masson, Annick, Lehoux, Claire, Brabant, Pascal, Pate, Philippe, Fontaine, Laurence, Sebok, Andra, Kuti, Tunde, Hegyi, Adrienn, Maldonado, Cristina, Llorente, Ana, García, Emilio, von Fircks, Holger, Hallberg, Marianne Lilja, Messerer, Maria, Larsson, Mat, Fredriksson, Helena, Adamsson, Viola, Börjesson, Ingmar, Fernández, Laura, Smillie, Laura, Wills, Josephine, Pedrero-Chamizo, Raquel, Meléndez, Agustín, Valtueña, Jara, Albers, Ulrike, Benito, Pedro J., Lorente, Juan José Gómez, Cañada, David, Urzanqui, Alejandro, Torres, Rosa María, Navarro, Paloma, and European Commission
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0301 basic medicine ,Male ,Mediterranean diet ,Adolescent ,Physiology ,Medicine (miscellaneous) ,030209 endocrinology & metabolism ,Low-grade inflammation ,Diet, Mediterranean ,Antioxidants ,Low grade inflammation ,Moderation ,03 medical and health sciences ,0302 clinical medicine ,Insulin resistance ,medicine ,Humans ,Inflammation ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,medicine.disease ,Healthy diet ,Inflammatory biomarkers ,Diet ,Europe ,Increased risk ,Adolescent Behavior ,HELENA study ,Female ,Sedentary Behavior ,business ,Biomarkers ,Biomedical sciences - Abstract
HELENA study group., [Aim]: To assess if a healthy diet might attenuate the positive sedentary–inflammation relation, whereas an unhealthy diet may increase the effect of sedentary behaviors on inflammatory biomarkers., [Methods]: In 618 adolescents (13–17 years) of the European HELENA study, data were available on body composition, a set of inflammation markers, and food intake assessed by a self-administered computerized 24 h dietary recall for 2 days. A 9-point Mediterranean diet score and an antioxidant-rich diet z-score were used as dietary indices and tested as moderators. A set of low-grade inflammatory characteristics was used as outcome: several cytokines in an inflammatory ratio (IL-6, IL-10, TNF-α, TGFβ-1), C-reactive protein, three cell-adhesion molecules (sVCAM-1, sICAM-1, sE-selectin), three cardiovascular risk markers (GGT, ALT, homocysteine) and three immune cell types (white blood cells, lymphocytes, CD3). Sedentary behaviors were self-reported and analyzed as total screen time. Multiple linear regression analyses tested moderation by diet in the sedentary behaviors–inflammation association adjusted for age, sex, country, adiposity (sum of six skinfolds), parental education, and socio-economic status., [Results]: Both diet scores, Mediterranean and antioxidant-rich diet, were significant protective moderators in the effect of sedentary behaviors on alanine-transaminase enzyme (P = 0.014; P = 0.027), and on the pro/anti-inflammatory cytokine ratio (P = 0.001; P = 0.004), but not on other inflammatory parameters., [Conclusion]: A higher adherence to the Mediterranean diet or an antioxidant-rich diet may attenuate the onset of oxidative stress signs associated by sedentary behaviors, whereas a poor diet seems to increase inflammation., The HELENA Study was carried out with the financial support of the European Community Sixth RTD Framework Programme (Contract FOODCT-2005-007034).
- Published
- 2017