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5 results on '"Mondardini V."'

1. Human and entomological surveillance of West Nile fever, dengue and chikungunya in Veneto Region, Italy, 2010-2012

Author

Bisoffi, Zeno, Capelli, G, Angheben, A, Giobbia, M, Conforto, M, Franzetti, M, Cattelan, Am, Raise, E, Rovere, P, Mulatti, P, Montarsi, F, Drago, A, Barzon, L, Napoletano, G, Zanella, F, Pozza, F, Russo, F, Rosi, P, Palù, G, Bisoffi, Z, Summer Fever Study Group, Concia, Ercole, Francavilla, E, Marranconi, F, Pellizzer, G, Scotton, P, Sgarabotto, D, Brugnaro, P, Del Bravo, P, Ferretto, R, Masini, G, Mondardini, V, Viviani, F, Piovesan, C, Postiglione, C, Cattai, M, Conti, A, Cusinato, R, Degani, M, Forti, A, Franchin, E, Gion, M, Marcante, R, Modolo, E, Pacenti, M, Rassu, M, Rigoli, R, Scarin, M, and Tonolli, Elisabetta

Subjects
Adult, Male, Veterinary medicine, Aedes albopictus, Adolescent, viruses, Dengue virus, Biology, medicine.disease_cause, West Nile, Dengue fever, Dengue, Young Adult, Culex pipiens, medicine, Animals, Humans, Chikungunya, Horses, Alphavirus infection, Aged, Aged, 80 and over, Travel, Surveillance, Alphavirus Infections, Outbreak, virus diseases, Dengue Virus, Middle Aged, medicine.disease, biology.organism_classification, Virology, Insect Vectors, Infectious Diseases, Culicidae, Italy, Epidemiological Monitoring, Chikungunya Fever, Female, Horse Diseases, Chikungunya virus, West Nile virus, Malaria, West Nile Fever, Research Article
Abstract

Background Since 2010 Veneto region (North-Eastern Italy) planned a special integrated surveillance of summer fevers to promptly identify cases of West Nile Fever (WNF), dengue (DENV) and chikungunya (CHIKV). The objectives of this study were (i) To increase the detection rate of imported CHIKV and DENV cases in travellers from endemic areas and promptly identify potential autochthonous cases.(ii) To detect autochthonous cases of WNF, besides those of West Nile Neuroinvasive Disease (WNND) that were already included in a national surveillance. Methods Human surveillance: a traveler who had returned within the previous 15 days from endemic countries, with fever >38°C, absence of leucocytosis (leukocyte count 38°C for

Published
2013

2. Clinical management of imported malaria in Italy: Results from a national cross-sectional survey in 2015

Author

Lepore, L., Vairo, F., D Abramo, A., Grilli, E., Corpolongo, A., Scorzolini, L., Nisii, C., Calleri, G., Castelli, F., Chirianni, A., Ippolito, G., Nicastri, E., Andreoni, M., Angarano, G., Anselmo, M., Ascoli Bartoli, T., Bartoloni, A., Bassi, P., Bevilacqua, N., Bisoffi, Z., Cacopardo, B., Caligaris, S., Calzetti, C., Casolari, S., Cassola, G., Chianura, L., Chiodera, A., Conforto, M., Coppola, N., Luca, A., Feasi, M., Ferrari, C., Filippini, P., Foti, G., Francavilla, E., Fusco, F. M., Tekle, S. G., Giancola, M. L., Giammario, A., Giobbia, M., Giordani, M. T., Gobbi, F., Gori, A., Grossi, P., Iacobello, C., Iannetta, M., Libanore, M., Luzzati, R., Magnani, G., Manfrin, V., Mariano, A., Mastroianni, C., Mazzotta, F., Mecocci, L., Mondardini, V., Montineri, A., Nicolini, L. A., Oliva, A., Palazzolo, C., Pasquale, G., Portelli, V., Puoti, M., Quirino, T., Santantonio, T. A., Sarmati, L., Sciotti, M. P., Scotton, P., Tomasoni, L. R., Toscanini, F., Tunesi, S., Elisa Vanino, Viale, P., Viganò, P., Viscoli, C., Vullo, V., Lepore, L., Vairo, F., D'Abramo, A., Grilli, E., Corpolongo, A., Scorzolini, L., Nisii, C., Calleri, G., Castelli, F., Chirianni, A., Ippolito, G., Nicastri, E., Andreoni, M., Angarano, G., Anselmo, M., Ascoli Bartoli, T., Bartoloni, A., Bassi, P., Bevilacqua, N., Bisoffi, Z., Cacopardo, B., Caligaris, S., Calzetti, C., Casolari, S., Cassola, G., Chianura, L., Chiodera, A., Conforto, M., Coppola, N., De Luca, A., Feasi, M., Ferrari, C., Filippini, P., Foti, G., Francavilla, E., Fusco, F. M., Tekle, S. G., Giancola, M. L., Giammario, A., Giobbia, M., Giordani, M. T., Gobbi, F., Gori, A., Grossi, P., Iacobello, C., Iannetta, M., Libanore, M., Luzzati, R., Magnani, G., Manfrin, V., Mariano, A., Mastroianni, C., Mazzotta, F., Mecocci, L., Mondardini, V., Montineri, A., Nicolini, L. A., Oliva, A., Palazzolo, C., Pasquale, G., Portelli, V., Puoti, M., Quirino, T., Santantonio, T. A., Sarmati, L., Sciotti, M. P., Scotton, P., Tomasoni, L. R., Toscanini, F., Tunesi, S., Vanino, E., Viale, P., Vigano, P., Viscoli, C., and Vullo, V.

Subjects
Plasmodium, Travel, Clinical Management, Imported Malaria, Italian National Survey, Plasmodium falciparum, Malaria, Antimalarials, Cross-Sectional Studies, Humans, Italy, Retrospective Studies, Surveys and Questionnaires
Abstract

In Italy, malaria continues to be one of the most common imported parasitoses; therefore, continuous surveillance of epidemiological data and clinical management is needed. In 2016, the National Institute for Infectious Diseases 'Lazzaro Spallanzani' in Rome promoted a retrospective questionnaire-based survey to assess the clinical management of imported malaria cases in Italy in 2015. The questionnaire was sent to 104 Tropical and/or Infectious Diseases Units in the country, and 37 of them filled out and returned the questionnaires. A total of 399 malaria cases were reported in 2015, mostly caused by Plasmodium falciparum and imported from Africa. Malaria chemoprophylaxis was correctly used by a minority of patients. Most patients presented with uncomplicated malaria and were treated orally. In severe cases, intravenous artesunate or quinine alone or in combination were administered, although one third of these severe cases received oral treatment. This retrospective survey reveals a lack of homogeneity in management of malaria-imported cases in Italy. Improvement of malaria chemoprophylaxis, standardization of clinical management of malaria cases and harmonization of oral and intravenous drug availability are needed throughout the country.

4. A Decrease in the Immunoglobulin G Antibody Response against the VlsE Protein of Borrelia burgdorferi Sensu Lato Correlates with the Resolution of Clinical Signs in Antibiotic-Treated Patients with Early Lyme Disease

Author

Roberto Cevenini, Silvia Accardo, Vittorio Sambri, Valeria Mondardini, Alessandra Moroni, Francesca Cavrini, Elisa Storni, Antonella Marangoni, Marangoni A., Sambri V., Accardo S., Cavrini F., Mondardini V., Moroni A., Storni E., and Cevenini R.

Subjects
Adult, Male, Microbiology (medical), Time Factors, Lipoproteins, Clinical Biochemistry, Immunology, Biology, DIAGNOSIS, THERAPY, Immunoglobulin G, Lyme disease, Bacterial Proteins, Antigen, Borrelia, medicine, Humans, Immunology and Allergy, Borrelia burgdorferi, Aged, Retrospective Studies, Immunosuppression Therapy, Antigens, Bacterial, Lyme Disease, Antibody titer, Early Localized Lyme Disease, Middle Aged, medicine.disease, biology.organism_classification, Antibodies, Bacterial, Anti-Bacterial Agents, biology.protein, VLSE PROTEIN, ANTIBODY RESPONSE, Female, Microbial Immunology, Antibody
Abstract

The purpose of this study was to evaluate the diagnostic performance of the LIAISON Borrelia Screen (Diasorin, Saluggia, Italy), a new automated immunoassay based on the chemiluminescent technology (chemiluminescence immunoassay). To assess whether a decrease in a negative value in the anti-VlsE immunoglobulin G (IgG) antibody titer was correlated with a positive response to treatment, a group of serially collected serum samples from 67 patients with culture-confirmed erythema migrans was retrospectively studied. All the patients had been treated with antibiotics and were free of disease within 3 to 6 months of follow-up. All the 15 patients who were found to be IgG positive at the time of enrollment and who were bled at least four times during the follow-up became IgG seronegative at 2 to 6 months posttreatment. These results indicate that a decline in the anti-VlsE antibody titer coincides with effective antimicrobial therapy in patients with early localized Lyme disease.

Published
2006

5. Comparative evaluation of three different ELISA methods for the diagnosis of early culture-confirmed Lyme disease in Italy

Author

Vittorio Sambri, Antonella Marangoni, Roberto Cevenini, Elisa Storni, Monica Sparacino, Valeria Mondardini, Francesca Cavrini, MARANGONI A., SPARACINO M., CAVRINI F., STORNI E., MONDARDINI V., SAMBRI V., and CEVENINI R.

Subjects
Microbiology (medical), Enzyme-Linked Immunosorbent Assay, Microbiology, Polymerase Chain Reaction, Sensitivity and Specificity, Serology, Comparative evaluation, Lyme disease, Borrelia, medicine, Humans, False Positive Reactions, Borrelia burgdorferi, IMMUNOBLOTTING, Lyme Disease, biology, SEROLOGY, Borrelia Burgdorferi Infection, Endemic area, Reproducibility of Results, General Medicine, bacterial infections and mycoses, biology.organism_classification, medicine.disease, Serum samples, Virology, Italy, Immunology, ELISA
Abstract

In this study the raising and development of the immune response to Borrelia burgdorferi infection in 45 Italian patients suffering from culture-confirmed Lyme borreliosis erythema migrans was investigated. A total of 95 serially collected serum samples were tested by using three different commercial ELISAs: recomWell Borrelia (Mikrogen), Enzygnost Borreliosis (DADE Behring) and Quick ELISA C6 Borrelia (Immunetics). The sensitivities of the ELISAs were as follows: Enzygnost Borreliosis IgM, 70.5 %; Quick ELISA C6 Borrelia, 62.1 %; recomWell Borrelia IgM, 55.7 %; recomWell Borrelia IgG, 57.9 %; and Enzygnost Borreliosis IgG, 36.8 %. In order to compare the specificity values of the three ELISAs, a panel of sera obtained from blood donors (210 samples coming from a non-endemic area and 24 samples from an endemic area) was tested, as well as sera from patients suffering from some of the most common biological conditions that could result in false-positive reactivity in Lyme disease serology (n = 40). RecomWell Borrelia IgG and recomWell Borrelia IgM were the most specific (97.1 % and 98.9 %, respectively), followed by Quick ELISA C6 Borrelia (96.7 %). Enzygnost Borreliosis IgG and IgM achieved 90.1 % and 92.3 % specificity, respectively. Sera that gave discrepant results when tested by the three ELISAs were further analysed by Western blotting.

Published
2005

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