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Distraction of drivers while driving on roadways results in the death of 1.2 million people, approximately every year around the globe. Even though there are several improvements made in road and vehicle design, the total number of accidents is higher. In 2015, 3,477 people were dead and 3,91,000 were injured during motor vehicle crashes associating distracted drivers. Our paper is aimed to prevent and reduce the rate of motor vehicle accidents that are caused by human errors and distraction during driving. We study the different postures of the driver by means of the hand localization, skin segmentation and facial data. In our paper, we propose a reliable deep-learning CNN model that attains 92% accuracy. more...

Advanced Driver Assistance Systems (ADAS) are used to assist driver by providing real-time information about cross traffic, parking space and so on. Such applications require a fair amount of processing to be done on the incoming video feed. It has been proved that the homography approach is efficient for ground plane detection. But, in the case of Road Plane Detection, the lane markings appear as obstacles when the SAD approach [1] is used. We propose a solution to this problem which involves using a Road Model and applying lane masking. We are able to get an accuracy of 88% to 96%. This technique is suitable for real time applications and we also provide benchmarks on a DSP processor, TMS320C6000 for the key functions used in this algorithm. more...

The DNA mismatch repair (MMR) system in mammalian cells not only serves to correct base mispairs and other replication errors, but it also influences the cellular response to certain forms of DNA damage. Cells that are deficient in MMR are relatively resistant to alkylation damage because, in wild-type cells, the MMR system is thought to promote toxicity via futile repair of alkylated mispairs. Conversely, MMR-deficient cells are sensitive to UV light, possibly due to the requirement for MMR factors in transcription-coupled repair of active genes. MMR deficiency has been associated with familial and sporadic carcinomas of the colon and other sites, and so, we sought to determine the influence of MMR status on cellular response to ionizing radiation, an agent commonly used for cancer therapy. Fibroblast cell lines were established from transgenic mice carrying targeted disruptions of one of three MMR genes in mammalian cells: Pms2, Mlh1, or Msh2. In comparison to wild-type cell lines from related mice, the Pms2-, Mlh1-, or Msh2-nullizygous cell lines were found to exhibit higher levels of clonogenic survival following exposure to ionizing radiation. Because ionizing radiation generates a variety of lesions in DNA, the differences in survival may reflect a role for MMR in processing a subset of these lesions, such as damaged bases. These results both identify a new class of DNA-damaging agents whose effects are modulated by the MMR system and may help to elucidate pathways of radiation response in cancer cells. more...