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Your search keyword '"Olff, M."' showing total 11 results
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11 results on '"Olff, M."'

2. Verstandelijke beperking

Author

Didden, H.C.M., Amelsvoort, T.A.M.J. van, Amelsvoort, T. van, Bekker, M., Olff, M., Mens-Verhulst, J., Amelsvoort, T. van, Bekker, M., Olff, M., and Mens-Verhulst, J.

Subjects
Learning and Plasticity
Abstract

Item does not contain fulltext

Published
2019

3. DHEAS and cortisol/DHEAS-ratio in recurrent depression: State, or trait predicting 10-year recurrence?

Author

Mocking, R. J. T., Pellikaan, C. M., Lok, A., Assies, J., Ruhé, H. G., Koeter, M. W., Visser, I., Bockting, C. L. H., Olff, M., Schene, A. H., Trauma and Grief, Leerstoel Bockting, Trauma and Grief, Leerstoel Bockting, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Clinical Psychology and Experimental Psychopathology, ANS - Amsterdam Neuroscience, Graduate School, Adult Psychiatry, APH - Amsterdam Public Health, and Other departments

Subjects
Male, DISORDER, SALIVARY CORTISOL, STRESS, Hydrocortisone, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13], Pituitary-Adrenal System, Cortisol, chemistry.chemical_compound, Endocrinology, Recurrence, ADOLESCENTS, polycyclic compounds, Longitudinal Studies, BRAIN, skin and connective tissue diseases, Depression (differential diagnoses), Hypothalamic-pituitary-adrenal (HPA) axis, Morning, Major depressive disorder (MDD), Dehydroepiandrosterone Sulfate, Middle Aged, Diabetes and Metabolism, Psychiatry and Mental health, Treatment Outcome, Trait, Major depressive disorder, Female, Biological psychiatry, Psychology, hormones, hormone substitutes, and hormone antagonists, Adult, medicine.medical_specialty, Hypothalamo-Hypophyseal System, endocrine system, Evening, PLASMA-CONCENTRATIONS, Remission, DEHYDROEPIANDROSTERONE-SULFATE, Dehydroepiandrosterone sulfate, Predictive Value of Tests, Internal medicine, PSYCHOTHERAPY, Dehydroepiandrosterone-sulphate (DHEAS), medicine, Humans, Saliva, Biological Psychiatry, Depressive Disorder, Major, Cognitive Behavioral Therapy, Endocrine and Autonomic Systems, COGNITIVE THERAPY, MAJOR DEPRESSION, medicine.disease, Cross-Sectional Studies, chemistry, Case-Control Studies, Cognitive therapy, human activities
Abstract

Item does not contain fulltext BACKGROUND: Major depressive disorder (MDD) has been associated with low dehydroepiandrosterone-sulphate (DHEAS), - particularly relative to high cortisol - although conflicting findings exist. Moreover, it is unclear whether low DHEAS is only present during the depressive state, or manifests as a trait that may reflect vulnerability for recurrence. Therefore, we longitudinally tested whether low DHEAS and high cortisol/DHEAS-ratio in recurrent MDD (I) reflects a trait, and/or (II) varies with depressive state. In addition, we tested associations with (III) previous MDD-episodes, (IV) prospective recurrence, and (V) effects of cognitive therapy. METHODS: At study-entry, we cross-sectionally compared morning and evening salivary DHEAS and molar cortisol/DHEAS-ratio of 187 remitted recurrent MDD-patients with 72 matched controls. Subsequently, patients participated in an 8-week randomized controlled cognitive therapy trial. We repeated salivary measures after 3 months and 2 years. We measured clinical symptoms during a 10-year follow-up. RESULTS: Remitted patients showed steeper diurnal DHEAS-decline (p

Published
2015

5. De posttraumatische stressstoornis

Author

Olff, M., Gersons, B., Hovens, H., Hovens, J. E. M., Megen, H. J. G. M., Erasmus School of Social and Behavioural Sciences, Amsterdam Neuroscience, Amsterdam Public Health, and Adult Psychiatry

Published
2006

10. [Untitled]

Author

Vermetten, H.G.J.M., Geuze, S.G., Wee, N.J.A. van der, Giltay, E.J., Elzinga, B.M., Olff, M., Sijbrandij, S.M., and Leiden University

Subjects
Depression, Military, Deployment, Mental health, Anxiety, Posttraumatic Stress Disorder, Trauma
Abstract

It is well known that military deployment can lead to mental health problems in veterans, but the long-term impact is still unclear. This thesis discusses the results of the PRISMO-study, a large cohort study in a group of Dutch Afghanistan veterans with a follow-up period of ten years. It shows that at ten years post-deployment, 8% of the cohort reported severe symptoms of posttraumatic stress disorder (PTSD). Agoraphobia, anxiety, depression, and hostility symptoms are also reported more frequently at ten years post-deployment compared to pre-deployment. Furthermore, this thesis demonstrates the large heterogeneity in PTSD symptom development among veterans. Of note is the delayed onset group that experienced increasing symptom levels between five and ten years post-deployment and did not show significant symptom reduction. The results from this thesis also show that various psychological factors, such as social support, and biological factors, such as DNA methylation, are associated with the development of PTSD or other mental health symptoms after deployment. Combining these factors in a prediction model for PTSD symptoms has not led to a useful screening instrument. It does, however, offer important leads for the identification of risk factors for PTSD and the development of intervention programs.

Published
2022

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