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Purpose: Increased eosinophil count (EC), mean platelet volume (MPV), and platelet count (PC) are important in vascular disorders which are main factors resulting in endothelial dysfunction. We aimed to investigate the association between MPV, and EC, with erectile dysfunction (ED). Materials and Methods: Two hundred thirty participants (130 patients with ED, and 100 healthy controls) were enrolled in this study. A detailed psychosexual history obtained, and physical, and laboratory examination were performed. International Index of Erectile Function (IIEF)-5 questionnaire was used to evaluate the erectile status objectively. IIEF-5 score was applied to all patients, and IIEF-5 score under 22 was considered as ED. The MPV, PC, and EC were compared between the two groups. Results: The mean age of the patients with ED and control group was 55.62 ± 8.90 years and 54.19 ± 4.10 years, respectively. MPV and PC levels were significantly higher in ED group (8.51 ± 1.00 fL and 8.16 ± 0.94 fL; 244.59 ± 57.3 cells/µL and 230.17 ± 48.44 cells/µL, respectively (P < .05). EC and white blood cell count were not significantly different between study and control groups. Conclusions: In our study a relationship was found between elevated MPV, and PC with ED. MPV and PC may be used as a biomarker in patients with ED.

Purpose: We aimed to investigate relationship between metabolic syndrome and calcium-oxalate stone formation. Materials and Methods: Between January 2008 and February 2015 we retrospectively investigated biochemical parameters and anthropometric characteristics (height, weight, and waist circumference) of 198 patients who had calcium-oxalate stones and we also randomly selected 200 participants who had no history of urolithiasis as the controls. Results: The presence of obesity increased the risk of calcium stones in both men (P = .003, OR = 2.92) and women (P = .03, OR = 2.18). Diabetes was significantly correlated to the risk of calcium stones (P = .04, OR = 1.94). However, when calculated separately for men and women, diabetic men had a higher risk of calcium-oxalate stone disease (P = .04, OR = 2.59), but diabetic women did not (P > .05). Hypertension also significantly increased the risk of calcium stones when compared with normotensive individuals (P = .0001, OR = 3.03). Conclusion: The risk for the development of calcium-oxalate stone disease is most significantly associated with the patient's body mass index and the presence of hypertension.