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Additional file 6: Figure S3. Construction and validation of a T cell-related prognostic signature (TRPS) for HCC. (A-B) The coefficient and partial likelihood deviance of TRPS. (C-D) Risk scores distribution, patients’ survival status, gene expression heatmap of TRPS in TCGA cohort and GSE14520cohort.

Additional file 2: Fig. S1. AFAP1L1 is significantly upregulated in GC tissues and cell lines. Fig. S2. High AFAP1L1 expression in GC promotes proliferation, invasion in vitro and growth, metastasis in vivo. Fig. S3. AFAP1L1 facilitates EMT process of GC cells. Fig. S4. AFAP1L1 is associated with integrin signaling and promotes ITGA5 expression in GC. Fig. S5. Western blot analysis of total RhoA, total Rac1 and their active forms in AGSshAFAP1L1, MKN74AFAP1L1 and their control cells.

Additional file 1: Table S1. The sequences of PCR primers used in this study. Table S2. The primary antibodies used in this study. Table S3. The association between AFAP1 expression and clinicopathological characteristics of GC patients. Table S4. The association between AFAP1L1 expression and clinicopathological characteristics of GC patients. Table S5. The association between AFAP1L2 expression and clinicopathological characteristics of GC patients. Table S6. Univariate and multivariate analysis of risk factors associated with overall survival of GC patients.

Additional file 2: Table S2. The Details and characteristics of TCGA and GSE14520 cohort.

Additional file 4: Figure S1. The CNV landscape of T cell markers in HCC.

Additional file 5: Figure S2. SNV landscape and prognostic value of T cell markers in HCC. (A-B) The SNV landscape of T cell markers in HCC. (C) Potential prognostic biomarkers identifying by univariate cox regression analysis.

Additional file 1: Table S1. The details and characteristics of singe cell HCC cases.

The complications of a total laminectomy can include epidural scar adhesion, secondary vertebral canal stenosis and lumbar instability. The aim of this study was to assess the ability of a combination of autologous micromorselized bone and polylactic acid (PLA) gel to stimulate bone repair within canine vertebral lamina defects, as well as to prevent peridural adhesion following a laminectomy. Twenty dogs underwent a L1, L3 and L5 laminectomy after a pre-computed tomography examination. The 60 laminectomies were divided into 4 groups, and underwent the following treatments: Group A were treated with a combination of autologous micromorselized bone and PLA gel (n = 16); Group B were treated with micromorselized bone only (n = 16); Group C with PLA gel only (n = 14); and Group D were left untreated as they were the blank controls (n = 14). Vertebral laminae were harvested at 4th and 8th weeks, and examined by computed tomography and histological staining. Significant bone regeneration was observed at 4 and 8 weeks in Groups A and B, although the newly formed bone in the latter group was more irregular in shape. Spinal canal cross-sectional areas in Group B decreased as compared with those in Group A(p < 0.05), and the degree of peridural adhesion in Groups A and C was significantly lower compared with Groups B and D (p < 0.05). These findings indicate that a combination of micromorselized bone and PLA gel may provide a better strategy for the treatment of spinal stenosis.

As the emerging portable electronic applications grows, for example, slim dvd-rw, portable dvd player and handset, techniques for managing power and reduce power consumption efficiently become more critical. In this paper, we provide our experience at power analysis and power optimization.

We continue the discussion of the numbers c(G) and r(G) defined in [1]. The following results are proved rXmZp= cXmZp=pm·1+p−2, m⩾3, where XmZp is the direct product of Zp.