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1. Additional file 2 of High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

Author

Serrano, Joan, Smith, Kathleen R., Crouch, Audra L., Sharma, Vandana, Fanchao Yi, Vargova, Veronika, LaMoia, Traci E., Dupont, Lydia M., Vanida Serna, Fenfen Tang, Laisa Gomes-Dias, Blakeslee, Joshua J., Hatzakis, Emmanuel, Peterson, Scott N., Anderson, Matthew, Pratley, Richard E., and Kyriazis, George A.

Subjects
human activities
Abstract

Additional file 1: Figure S1. Participant inclusion flowchart. Figure S2. Longitudinal treatment effects glucose and hormonal excursions during an oral glucose challenge in humans. Figure S3. Treatment compliance and intestinal gene expression in mice. Figure S4. Pre-treatment comparisons of gut microbial diversity and composition (genus) in humans. Figure S5. Pre-treatment comparisons and treatment effects on gut microbial diversity and composition in humans. Figure S6. Pre-treatment comparisons of gut microbial diversity and composition (genus) in mice. Figure S7. Pre-treatment comparisons and treatment effects on gut microbial diversity and composition in mice. Figure S8. Pre-treatment fecal metabolomics in humans and mice. Figure S9. Experimental design of the human and mouse studies.

Published
2021
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