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6 results on '"Puzzo, Lidia"'

3. [Location of epi-myoepithelial markers (EMA, keratin, protein S-100) and connective tissue markers (vimentin) in carcinoma with pseudosarcomatous metaplasia of the human breast. A study of 3 cases using a dual color immunohistochemical technic]

Author

Lanzafame, Salvatore, Puzzo, Lidia, and Gangemi, P.

Subjects
Adult, Pseudosarcomatous metaplasia, Membrane Glycoproteins, Carcinoma, Mucin-1, S100 Proteins, Breast Neoplasms, Middle Aged, Immunohistochemistry, Breast, Phyllodes Tumor, Biomarkers, Tumor, Humans, Keratins, Vimentin, Female
Published
1987

6. [Medullary carcinoma of the breast. Co-expression of keratin intermediate filaments and protein S-100 in tumor cells]

Author

Puzzo, Lidia and Lanzafame, Salvatore

Subjects
Adult, Aged, 80 and over, Carcinoma, S100 Proteins, Intermediate Filaments, Breast Neoplasms, Middle Aged, Breast, Medullary carcinoma, Myoepithelial differentiation, Carcinoembryonic Antigen, Humans, Keratins, Vimentin, Female, Cytoskeleton, Aged
Abstract

We have chosen 10 medullary carcinomas from a retrospective investigation on 450 cases of breast carcinoma (2.2%), according to the histomorphological criteria of Ridolfi and colleagues. By immunoperoxidase staining, we have evaluated the distribution of keratin and vimentin intermediate filaments, of CEA and S-100 protein in cancer cells. A widespread positivity to keratins has been proved in 70% of medullary carcinomas. Numerous neoplastic cells have coexpressed S-100 protein. We hypothesize the epithelial and myoepithelial "intermediate" differentiation of keratin and S-100 protein positive tumour cells.

Published
1989

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