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4 results on '"Queen, Rachel"'

1. Additional file 3 of Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype

Author

Khasawneh, Ramada R., Kist, Ralf, Queen, Rachel, Hussain, Rafiqul, Coxhead, Jonathan, Schneider, Jürgen E., Mohun, Timothy J., Zaffran, Stéphane, Peters, Heiko, Phillips, Helen M., and Bamforth, Simon D.

Subjects
stomatognathic diseases, animal structures, embryonic structures, hemic and immune systems, chemical and pharmacologic phenomena
Abstract

Additional file 3. Apoptosis and cell proliferation are not affected in Pax9–/– and Pax9–/–;Msx1+/– mutant embryos on a congenic CD1 background.

Published
2021
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2. Additional file 1 of Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype

Author

Khasawneh, Ramada R., Kist, Ralf, Queen, Rachel, Hussain, Rafiqul, Coxhead, Jonathan, Schneider, Jürgen E., Mohun, Timothy J., Zaffran, Stéphane, Peters, Heiko, Phillips, Helen M., and Bamforth, Simon D.

Subjects
stomatognathic diseases, lipids (amino acids, peptides, and proteins), hemic and immune systems, chemical and pharmacologic phenomena, complex mixtures
Abstract

Additional file 1. Caudal PAA defects in CD1-Pax9–/– and CD1-Pax9–/–;Msx1+/– embryos.

Published
2021
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4. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

Author

Sungnak, Waradon, Huang, Ni, Bécavin, Christophe, Berg, Marijn, Queen, Rachel, Litvinukova, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Sampaziotis, Fotios, Worlock, Kaylee B, Yoshida, Masahiro, Barnes, Josephine L, and HCA Lung Biological Network

Subjects
HCA Lung Biological Network, 3. Good health
Abstract

We investigated SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in single-cell RNA-sequencing data from multiple tissues from healthy human donors. We co-detected these transcripts in specific respiratory, corneal and intestinal epithelial cells, potentially explaining the high efficiency of SARS-CoV-2 transmission. These genes are co-expressed in nasal epithelial cells with genes involved in innate immunity, highlighting the cells' potential role in initial viral infection, spread and clearance. The study offers a useful resource for further lines of inquiry with valuable clinical samples from COVID-19 patients and we provide our data in a comprehensive, open and user-friendly fashion at www.covid19cellatlas.org.

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