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Appendix. In this file, we present a list of variables and definitions used in the manuscript (Section A). Detailed pseudocode for the SParSE++ driver, multi-level CE method, and inverse biasing method are given in Section B. Section C contains two tables regarding the yeast polarization process. The first table (Table 4) lists thirty randomly generated initial reaction rates that were used to run the SParSE and SParSE++ algorithms. The second table (Table 5) contains an algorithmic breakdown for each of the initial reaction rates. (PDF 234 kb)