Pınar KORKMAZ, Behice KURTARAN, Şule ÖZDEMİR ARMAĞAN, Hale TURAN ÖZDEN, Fatma KAÇAR, Selma ATEŞ, Gül DURMUŞ, Fulya BAYINDIR BİLMAN, Yeşim UYGUN KIZMAZ, Aziz Ahmad HAMİDİ, Burcu ÖZDEMİR, Aslıhan BURCU YIKILGAN, Pınar FIRAT, Asuman İNAN, Gülay OKAY, Mehmet Emirhan IŞIK, Ayşe BUT, Kenan UĞURLU, Rezan HARMAN, Büşra ERGÜT SEZER, Elif DOYUK KARTAL, Ferit KUŞÇU, Alper ŞENER, Duru MISTANOĞLU ÖZATAĞ, Elif TÜKENMEZ TİGEN, Özgür DAĞLI, Funda KOÇAK, Hülya KUŞOĞLU, Buket ERTÜRK ŞENGEL, Aslıhan DEMİREL, Hasan NAZ, Canan AĞALAR, Derya ÖZTÜRK ENGİN, İlyas DÖKMETAŞ, Nur CANCAN GÜRSUL, Fatma YILMAZ KARADAĞ, Mehmet Umut ÇAYIRÖZ, Yeşim KÜREKÇİ, Ayten KADANALI, Zeynep Şule ÇAKAR, Ümit SAVAŞÇI, İlknur ERDEM, Sabahat ÇAĞAN AKTAŞ, and Acibadem University Dspace
Introduction: In this study, we aimed to determine the risk factors associated with inadequate empirical antibiotherapy (IEAT) and hospital-related mortality in elderly patients being treated for upper urinary tract infections (UTI). Materials and Methods: This study included individuals aged 65 years and over who were hospitalized after being diagnosed of communityacquired UTI or community-onset healthcare-associated UTI and followed-up in clinics and/or intensive care units (ICU) of 33 hospitals between March and September 2017. Results: A total of 525 patients (48% males; mean age: 76.46±7.93 years) were included in the study. Overall, 68.2% of the patients were hospitalized through the emergency department and 73.9% of patients were followed-up for pyelonephritis. Gram-negative, Gram-positive, and Gram-negative and positive mix growths were determined in 88%, 9.3%, and 2.7% of urine cultures, respectively. Fifty-six (10.7%) of the patients died. In multivariate analysis, the presence of chronic obstructive pulmonary disease [Odds ratio (OR): 2.278], age 85 years and over (OR: 2.816), admission to the ICU (OR: 14.831), and IEAT (OR: 2.364) were independent factors that significantly affected mortality. The presence of a urinary catheter, being followed-up in the ICU, benign prostate hypertrophy, use of antibiotics other than piperacillin-tazobactam and carbapenem were determined as independent factors that significantly affected IEAT (p