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Introduction: An understanding of the long-term psychosocial impact of paediatric haematopoietic stem cell transplantation (HSCT) for nonmalignant diseases is needed to optimize pre-HSCT counselling, supportive care and long-term follow-up programmes after HSCT for this group of patients and caregivers. Methods: This qualitative study included 14 patients who underwent transplantation for a nonmalignant disease during childhood. In-depth interviews were held online to explore patients' perspectives on the long-term psychosocial impact of HSCT on their lives. The results were analysed based on the Grounded Theory approach. Results: Patients' median age at the time of the interview was 19 years (range: 14-49), and the median years after HSCT was 12 years (range: 3-33). Four main themes were identified: (1) doing okay, (2) experiencing persistent involvement with healthcare services, (3) influence on relationships with loved ones and (4) impact on the patient's life course. Subthemes extracted were doing okay, feeling of being cured, health limitations, sense of vulnerability, ongoing connection to the hospital, acceptance, friendship, family relations, development of own identity, not taking life for granted, social development, impact on (school) career and thinking about the future. Conclusions: Patients reported active coping strategies and resilience after this high-impact treatment. The data highlight the need for patient-adjusted supportive care, indicating more need for supportive care in the long-term outpatient clinic. Patient Contribution This study included patients as participants. Caregivers were approached if patients were below a certain age. Additionally, preliminary results were presented during a patient conference day.

Ambient seismic noise acquired in the Cerdanya Basin (Eastern Pyrenees) is used to assess the capability of different methodologies to map the geometry of a small-scale sedimentary basin. We present results based on a 1-year long broad-band deployment covering a large part of the Eastern Pyrenees and a 2-months long high-density deployment covering the basin with interstation distances around 1.5 km. The explored techniques include autocorrelations, ambient noise Rayleigh wave tomography, horizontal to vertical spectra ratio, and band-pass filtered ambient noise amplitude mapping. The basement depth estimations retrieved from each of these approaches, based on independent datasets and different implicit assumptions, are consistent, showing that the deeper part of the basin is located in its central part, reaching depths of 600-700 m close to the Têt Fault trace bounding the Cerdanya Basin to the NE. The results from the different methodologies have an overall consistency, although significant differences appear in some zones. The results show also that when high-density seismic data are available, mapping the ambient noise amplitude in a selected frequency band is a valid tool to quickly map the sedimentary 3D geometry. Besides this methodological aspect, our results help to improve the geological characterization of the Cerdanya Basin and will provide further constraints to refine the seismic risk maps of an area of relevant touristic and economic activity., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

The Maltese islands, approximately 314 km2 in area with a high population density, face high levels of water stress due to low amounts of rainfall and a dependence on groundwater abstraction. Until now, in-situ borehole readings have been the only method utilised to monitor the quantitative status of groundwater in the Maltese islands. This study investigates an innovative, cost-effective approach to groundwater monitoring in a small island environment by computing cross-correlations and autocorrelations of ambient seismic noise recorded on seismic networks of broadband and short-period stations in the Maltese islands. We compare the borehole readings of groundwater levels ranging from 0.28-3.39 m above mean sea level with the variations in seismic velocity (δv/v). We apply appropriate filters for the broadband and short-period stations of 0.1-1 Hz and 0.3-3 Hz, respectively. The results demonstrate clear seasonal changes in the seismic velocities, which can be correlated with changes in groundwater levels in nearby boreholes. We find that variations of the δv/v from autocorrelations are more pronounced than the cross-correlation, with maximum seismic velocity changes of ~2% and ~0.3% respectively. The quality of the δv/v deteriorates at longer interstation distances where seasonal variations are less noticeable. Presumably, this is because longer interstation paths tend to traverse more complex geology, different types of aquifers, or even the sea., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Purpose To determine the clinical and radiological outcomes of hybrid-design- (HD) and bone-level (BL) implants for bar-retained mandibular implant-overdentures (IODs). Methods For this retrospective study, edentulous patients who had received maxillary complete dentures and mandibular bar-retained IODs were invited for a follow-up assessment. Implant survival, implant success and health of peri-implant tissues were assessed on an implant level-based analysis. Patient-based parameters served to identify risk factors for peri-implant bone loss, presence of peri-implantitis and success. Results Eighty patients (median age 72.72 [67.03; 78.81] years, 46 females) with 180 implants (median follow-up 12.01 [10.82; 21.04] years) were assessed. There was no difference concerning the rate of implant failure (p = 0.26), or peri-implantitis (p = 0.97) between HD and BL implants. Solely in one study group, there was the presence of peri-implant pus. Implant success was higher in BL implants with one group being notably higher than the comparing groups (p = 0.045). For bone loss, a width of keratinized mucosa (KM) ≤ 1 mm (p = 0.0006) and the presence of xerostomia (p = 0.09) were identified as risk factors. Smoking (p = 0.013) and a higher body mass index (BMI) (p = 0.03) were a risk factor for peri-implantitis. As risk factors for reduced implant success, a small width of KM (p = 0.003) and the presence of xerostomia (p = 0.007) were identified. Conclusions For mandibular bar-retained IODs, both BL and HD implants are mostly successful. A minimum of 1 mm KM around implants and normal salivary flow are relevant factors for implant success and stable peri-implant bone levels. Smoking and a high BMI are potential risk factors for peri-implantitis.

ObjectivesThis study aimed to obtain a consensus on oral health policy, access to dental care, oral hygiene measures and training levels.BackgroundPoor oral health is widespread in care-dependent older people, but no consensus for a minimum standard of oral health care exists yet.MethodsThe e-Delphi approach was applied to a selected panel of interdisciplinary experts. Data analysis was based on three measurements: (a) ≥70% of experts’ opinion fall into category “agree or strongly agree,” (b) median score on the 5-point Likert scale ≥4, (c) interquartile range ≤1.ResultsA total of 31 experts from 17 European countries participated in this survey. Agreement was achieved for a compulsory dental examination when an elder is admitted to a long-term care (LTC) facility. Older people should brush their teeth twice/day and regularly clean interproximal spaces and oral mucosa. Dentures should be rinsed after meals and cleaned twice/day. The use of denture cleansing tablets was considered necessary. Dentures should be removed before sleeping and stored dry. A 5000 ppm fluoride toothpaste should be applied daily in elder with high caries risk. A short report on the oral health status of the elder should be included in the geriatric assessment. All experts concluded that the knowledge and the training in oral health care for caregivers and family members of care-dependent older people were imperative.ConclusionsUsing the e-Delphi method, multidisciplinary healthcare professionals from different countries agreed on certain cardinal recommendations for a standard oral health care for care-dependent older people.

Induced seismicity and surface subsidence are adverse effects of natural gas and geothermal energy production that may present barriers to their use as low-carbon alternatives to coal and oil. The driving force for these unwanted effects is compaction of the reservoir, which can potentially be mitigated by injecting (pressurized) fluids that restore the pore pressure and chemically inhibit compaction. We conducted uniaxial compaction experiments on quartz sand aggregates to investigate the effect of pore fluid chemistry on time-dependent compaction (creep). In addition to a low-vacuum (dry) environment, supercritical fluids (N2, CO2, and wet CO2), simple aqueous solutions (three HCl solutions and a NaOH solution), and complex aqueous solutions with additives (AlCl3, AMP, and washing detergent) were employed. N2, CO2, and fluids containing scaling inhibitor (AMP), as well as wastewater (detergent solution) are generally considered for injection. Compaction creep was enhanced in fluid-saturated environments compared to dry. Wet CO2 caused more creep with faster strain rates than the relatively dry CO2 and N2 environments. Experiments conducted with simple aqueous solutions exhibited a clear pH dependency. The complex aqueous solutions enhanced creep compared to their simple solution counterpart with similar pH. Based on acoustic emission data and microstructural analyses, we inferred that compaction creep was controlled by subcritical crack growth, aided by water, hydroxyl ions, and additives. If microcracking also controls compaction in reservoir sandstones, these results indicate that injection of supercritical fluids or acidic solutions may mitigate reservoir compaction.

A plethora of geophysical, geo- chemical, and geodynamical observations indicate that the terrestrial planets have differentiated into silicate crusts and mantles that surround a dense core. The latter consists primarily of Fe and some lighter alloying elements (e.g., S, Si, C, O, and H) [1]¿. The Martian meteorites show evidence of chalcophile element depletion, suggesting that the otherwise Fe-Ni- rich core likely contains a sulfide component, which influences physical state.

Planetary crusts are the results of mantle differentiation, so their thickness provides important constraints on the thermochemical evolution of a planet, including its heat budget and mantle rheology. Information on crustal layering and seismic velocities can also provide important constraints on porosity and geochemistry of the crust. Here, we use data from the InSight mission, which landed in November 2018, to provide seismological constraints on the crustal layering and thickness of Mars for the first time. Results are mainly based on Ps-receiver functions from three events with magnitudes between 3.1 and 3.6 at distances between 27.5° and 47° (±10°) from the lander, originating in the Cerberus Fossae region, the only events, so far, with clear, impulsive P-wave onsets and known epicenter. Ps-receiver functions use converted phases in the P-wave coda to derive information on discontinuities beneath the seismometer. Due to the limited number of events and the small epicentral distance range covered, inversions of the data are still ambiguous. Two sets of models can explain the waveforms, one consisting of a two-layer crust of about 20 to 23 km thickness, the other having a three-layer crust of about 40 to 45 km thickness. By excluding crustal thicknesses in excess of 45 km at the landing site, we can constrain the global average crustal thickness of Mars to be less than 70 km. Both model types also agree with S-receiver functions for two events and seismic P-waves reflected in the crust and extracted from autocorrelations using the coda of different types of marsquakes as well as the background wavefield. Furthermore, the results are compatible with independently conducted moment tensor inversions for a limited number of events as well as modeling of the wave-propagation of high-frequency events. We find low seismic P-wave velocities below 3.4 km/s within the upper approximately 10 km, likely indicating a high porosity. For the Moon, we present Sp-receiver functions for three Apollo landing sites, including the first application of this method to Apollo 15 and 16 data. Data are compatible with a two-layer crust beneath a thin, low-velocity regolith layer and a crustal thickness of 35 to 45 km, with an increased thickness at the Apollo 15 and 16 sites compared to the Apollo12 location.

The Spanish Central System is the most relevant topographic feature in central Iberia. Along with the surrounding Duero and Tajo basins it presents an anomalous high elevation. This high topography is, most probably, the result of a combination of deep and surface processes. The crustal thickness, geometry of the Moho discontinuity and the crustal architecture are the main targets of current research efforts developed in the area. As part of a multi-seismic project limited controlled source data has been acquired, jointly with ambient noise seismic records. The preliminary results provide relatively strong constraints on the deep structure of the Spanish Central System. The ambient seismic noise records were acquired by a set of 24 short period (2 Hz) seismic stations deployed along a 120 km long NW-SE-trending profile with a 4.8 km average spacing. The transect crossed the southern branch of the mountain range. The stations recorded the ambient seismic field continuously for a month. Processing consisted on: phase autocorrelation of the seismic noise to retrieve the zero-offset reflection response at the receivers and, time-frequency domain phase weighted stack used to stack the auto correlations. For calibration and, along the same transect, over 500 TEXANS were deployed to record a wide-angle shot gather. The recording units with an approximate station spacing of 400 m recorded relatively high amplitude crustal and Moho events. The lower crust and the crust-mantle transition are constrained by both data sets. Further more small crustal discontinuities and structures are interpreted and correlated with surface geology features. The results of the processing are compared to synthetic models to certify the validity of our interpretations, Research support, Ref: CGL2016-81964-REDE, , EU grant 730900

[EN]This presentation describes the process to retrieve Moho reflections from autocorrelation of seismic noise data

The strongest seismic noise, called secondary microseisms, is generated by ocean wave interactions and we model this noise using the theory of Longuet-Higgins generalized to random ocean gravity waves. Noise sources are computed with an ocean wave model that takes into account coastal reflections. Variations of the source locations are consistent with seasonal variations of seismic noise spectra. Noise spectra are modelled over many years for stations representative of various environments such as continent, island and polar area to constrain, for each environment, the parameters involved in the modelling. For each station, we quantify the trade-off between ocean wave coastal reflection and seismic wave attenuation that both affect the amplitude of the seismic spectrum. We show their adjustment and the need, at some stations, for an extra parameter representing the three-dimensional (3-D) seismic wave propagation effects. The long-term analysis demonstrates the stability of the fitted parameters which can be used in future noise studies. The modelling enables to reproduce the frequency content and amplitude of the different noise peaks of seismic spectra. The strongest peaks are generated by deep ocean sources whereas coastal reflections generate numerous smaller sources that contribute to the background noise level. Coastal reflection effects can be neglected only for the Pacific island station PPT. The modelling also reproduces the peculiar noise spectrum variation in Antarctica (station DRV) which is related to the presence of sea ice around the stations. © 2012 The Authors Geophysical Journal International © 2012 RAS., This is IPGP contribution number 3325. The authors thank’s GEO-SCOPE network for providing the data used in this study. MS acknowledges support by ILink2010-0112 and CGL2009-09727 (Rifsis)

Fourth IASTED International Conference on Signal Processing, Pattern Recognition, and Applications (SPPRA '07), 14-16 February 2007, Innsbruck, Austria.-- 6 pages, 10 figures, The S-transform is a powerful tool for non stationary signals which allows the visualisation of local spectra. In this communication, we modify the definition of an inverse of the S-transform to make it exact. Then, we study the influence of discretising the S-transform and its inverses. Finally, one of the main interests of the S-transform is the possibility to filter in frequency and time at the same time. We show the different side effects generated by the two existing inverse S-transforms when filtering, This work was supported by the project SigSensual ref. CTM2004-04510-C03-02 and the Consolider-Ingenio 2010 Nr. CSD2006-00041 program. C. Simon and S. Ventosa are financed by the I3P program. M. Schimmel is supported by the Consolider-Ingenio 2010 Nr. CSD2006-00041 program

Fourth IASTED International Conference on Signal Processing, Pattern Recognition, and Applications (SPPRA '07), 14-16 February 2007, Innsbruck, Austria.-- 6 pages, 4 figures, In geophysics, the frequency-wave number (f–k) filter is a common tool which allows to distinguish between seismic phases through their apparent velocity. However, this filter is based on a two dimensional Fourier transform, so it is not well adapted to the non-stationary nature of 2-D signals present in geophysics, because of its lack of timespace resolution. In order to solve this limitation, we introduce a new tool called adaptive slowness filter, inspired by spatial averaging and Radon filters. Our procedure can attenuate undesired signals with a known slowness (inverse of velocity) and time-distance location, while mantaining the other signals with different location or slowness with minimal distortion, This work was supported by the project SigSensual ref. REN2003-08341-C03-C01-02 and CTM2004-04510-C03-02. C. Simon and S. Ventosa are financed by the I3P program. M. Schimmel is supported through the Ramon y Cajal and the Consolider-Ingenio 2010 Nr. CSD2006-00041 program

The article describes the medical and dental procedures for four treatment sessions with the Digital Denture Professional (DDP) system. First, conventional preliminary dental impressions of the full arch are taken to achieve accurate jaw positioning records. The study models and patient data are digitalised using a laboratory scanner. The dental lab technician then constructs and mills custom impression trays and a mount as an intraoral instrument. A closed-mouth impression is then taken to record vertical dimensions and central relation position. After this is digitalised in the laboratory, DDP add-on software is used to virtually design the full dental implants and mill monolithic test implants. These can be tested for aesthetics, function and phonetics in the third session. The testing phase can also be skipped on request. In the last session, the final dental implants are fitted for the patient. The patients individual data are precisely recorded and digitally processed, which ensures the results are always as planned. The patient benefits from the spared time and costs. The range of care will be expanded in future to include reconstructions using implants. The digitalisation of the technique would be ideal for the planning and provision of digital implant prosthetics.

The structure of the Taiwan mountain belt is thought to be that of an imbricate thrust and fold belt developed in a forward breaking sequence above a shallowly dipping basal detachment. In recent years, however, a growing amount of seismicity data from the internal part of the mountain belt indicates the existence of widespread fault activity in the middle and lower crust, suggesting that deeper levels of the crust must be involved in the deformation than predicted by the shallow detachment, imbricate thrust belt model. To address this issue, we present new geological mapping, together with earthquake focal mechanism and seismic energy release data from the central part of Taiwan. We concur with the interpretation that the foreland basin part of the Western Foothills comprises an imbricate thrust system that is developing as a forward breaking sequence that is structurally and kinematically linked to a basal detachment at between 7 and 10 km depth. To the east of the foreland basin, however, in the Hsuehshan and Central Ranges, our data show the presence of two fault systems. An earlier, inactive thrust system with a well-developed cleavage is cut by a system of steeply dipping active faults that penetrate to a depth of 25 to 30 km or more. In the Hsuehshan Range, the second fault system is best represented by a structural and kinematic model in which this part of the mountain belt forms a zone of transpression with a structural architecture similar to that of a crustal-scale positive flower structure. Eastward, in the Central Range, Mesozoic basement rocks are over thrusting strongly folded and cleaved deep water sediments of the first, now inactive, thrust system. The involvement of deep crustal levels and Mesozoic basement in the second fault system is suggestive of the reactivation of preexisting basin-bounding faults that were located on the Eurasian continental margin., This research was carried out with the aid of grants by CSIC – Proyectos Intramurales 2006 3 01 010, and MICINN:CGL2009-11843-BTE.

Ripartizione della deformazione in Taiwan Centrale: nuove prospettive da dati di geologia di superficie, meccanismi focali dei terremoti, rilascio di energia sismica e misure GPS lungo il sistema di faglie transpressivo Shuilikeng. Il sistema di faglie transpressivo Shuilikeng è una zona di faglia ad alto angolo che separa le Western Foothills dall'Hsuehshan Range, le due principali unità tettoniche del settore centro-occidentale della catena di Taiwan costituite dai sedimenti del margine continentale passivo Asiatico. Si presenta una nuova cartografia geologica integrata con dati geofisici per porre nuovi vincoli e meglio definire la ripartizione della deformazione lungo questo sistema di faglie.