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Adherence to antiretroviral therapy (ART) is critical to suppress HIV replication and prevent its transmission to others. However, the definition of adherence, thresholds for optimal viral suppression, and how adherence challenges should be best addressed is unclear. Therefore, this study aims to synthesize the similarities and diverse approaches to adherence to defining ART adherence and interventions to address barriers within HIV care. A scoping review will be conducted on adult HIV clinical guidelines and guideline updates from developed countries following guidance from the Joanna Briggs Institute, which includes the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Databases will include Medline, Embase, and CINAHL. A search of the grey literature will be conducted through Canadian Medical Association Infobase, National Institute for Health and Care Excellence, Guideline Central, Turning Research Into Practice (TRIP), and Emergency Care Research Institute (ECRI) Guidelines Trust. For data collection, one reviewer will screen all records and full-texts, while a second reviewer will assess 20% of the texts for inter-rater reliability. Data regarding definitions of adherence, adherence thresholds, barriers to adherence, and interventions for adherence will be charted in tables. A synthesis of data will be performed using content analysis on NVivo software.

Background and purpose The clinical results of THR may be improved by correct femoral torsion. We evaluated the stem position by postoperative CT examination in 60 patients.Methods 60 patients requiring total hip arthroplasty were prospectively enrolled in this study. Minimally invasive THR was performed (anterior approach) in a lateral decubitus position and each patient underwent a postoperative CT examination. The position of the stem was evaluated by an independent external institution.Results Stem torsion ranged from –19° retrotorsion to 33° antetorsion. Normal antetorsion (i.e 10–15° according to Tonnis) was present in 5 of 60 patients, so the prevalence of abnormal stem antetorsion was 92% (95% CI: 82–97). We found a stem antetorsion outside the range of 0–25° in 21 of 60 hips. Women had a higher mean stem antetorsion (8.0° (SD 11)) than men (1.5° (SD 10)).Interpretation Postoperative stem antetorsion shows a high variability and is gender-related. We suggest precise assessment of stem antetorsion ...

We evaluated observer agreement for 68Ga-DOTATATE PET/CT interpretations in patients with neuroendocrine tumor (NET). Methods: 68Ga-DOTATATE PET/CT was performed on 50 patients with known or suspected NET of the small bowel (n = 19), pancreas (n = 14), lung (n = 4), or other location (n = 13). The images were reviewed by 7 observers, who used a standardized interpretation approach. The observers were classified as having a low level of experience (