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Your search keyword '"Semrau, S."' showing total 2 results
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2 results on '"Semrau, S."'

1. Common and rare variant associations with clonal haematopoiesis phenotypes

Author

Kessler, M.D., Damask, A., O'Keeffe, S., Banerjee, N., Li, D., Watanabe, K., Marketta, A., VanMeter, M., Horowitz, J., Tang, J., Kosmicki, J.A., Rajagopal, V.M., Zou, Y., Houvras, Y., Ghosh, A., Gilles, C., Mbatchou, J., White, R.R., Verweij, N., Bovijn, J., Parikshak, N.N., LeBlanc, M.G., Jones, M., Glass, D.J., Lotta, L.A., Cantor, M.N., Atwal, G.S., Locke, A.E., Ferreira, M.A.R., Deering, R., Paulding, C., Schuldiner, A.R., Thurston, G., Ferrando, A.A., Salerno, W., Reid, J.G., Overton, J.D., Marchini, J., Kang, H.M., Baras, A., Abecasis, G.R., Jorgenson, E., and Semrau, S.

Subjects
Multidisciplinary, Cardiovascular Diseases, Humans, COVID-19, Clonal Hematopoiesis
Abstract

Clonal haematopoiesis involves the expansion of certain blood cell lineages and has been associated with ageing and adverse health outcomes

Published
2022
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2. Sporadic endolymphatic sac tumor - a diagnostic and therapeutic challenge

Author

Künzel, J., Agaimy, A., Hornung, J., Lell, M., Ganslandt, O., Semrau, S., and Johannes Zenk

Subjects
Adult, Male, Time Factors, Biopsy, Temporal Bone, Case Report, Immunohistochemistry, Magnetic Resonance Imaging, Neurosurgical Procedures, Treatment Outcome, Medizinische Fakultät, Biomarkers, Tumor, Humans, Neoplasm Invasiveness, Radiotherapy, Adjuvant, ddc:610, Cranial Irradiation, Endolymphatic Sac, Ear Neoplasms
Abstract

Endolymphatic sac tumor (ELST) is a rare low-grade locally aggressive neoplasm of the inner ear that may occur sporadically or in the setting of von Hippel-Lindau syndrome. We herein present a case of sporadic ELST in a 39-year-old man, treated using an interdisciplinary approach (surgery + radiotherapy), with a 10-year follow-up. The patient presented with hearing loss of sudden onset. The treatment of choice for ELST is radical tumor resection, which is associated with a good long-term prognosis. Remission may last for years, but there may be local recurrences, probably as a result of incomplete resection. Adjuvant radiotherapy is an option in case of recurrence and could be discussed after incomplete resection. The purpose of this report is to call attention to ELSTs, which are difficult to diagnose due to their rarity and variety of presentations.

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