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Realizing functional space systems using flight-tested components is problematic in developing economies, as such components are costly for most institutions to sponsor. The B.Sc. project, Subsystems for 2nd Iteration Cairo University Cube-Satellite, addresses technology demonstration using commercially available electronics and low cost computing platforms, such as Android phones and Raspberry Pi Linux micro-computer as computing hardware. As for software, the project makes use of open-source modules and locally developed code to implement needed functionalities, in addition to a mechanism to operate a virtual desktop Linux OS in parallel to an Android application. The paper aims to demonstrate the significance, operation design, and problem solving of such approaches. The paper concludes with future prospects for improving upon the proposed computing systems

A new structure of composite right/left-handed (CRLH) coupled line coupler compact with high coupling value is presented and compared with the conventional coupled line microstrip coupler. Instead of the normal conductor (Copper) used in strip line, a YBCO thin film high temperature superconductor (HTS) is replaced to achieve superior performance. A high directivity of the coupled line was achieved by using superconductor. The coupled line coupler was designed based on the unit cell fabricated and it has good measured results. KEYWORDS Directional Couplers, Coupled Line, Microstrip, Metamaterial & Superconductor &nbsp

Two series of novel 1,3,4-thiadiazole-benzofuran and 1,3,4-thiadiazole-furochromene derivatives were synthesized through heterocyclization of alkyl 2-(1-(6-hydroxy-4,7-dimethoxybenzofuran-5-yl)ethylidene)hydrazine-1-carbodithioate 3a–f and 2-(1-(5-methoxy-8-methyl-2,6-dioxo-2,6-dihydropyrano[3,2-g]chromen-3-yl)ethylidene)hydrazinecarbothioamide 9a,b with various hydrazonoyl halides, respectively. The structure of the newly synthesized products was elucidated through elemental analysis, spectral data and alternative routes whenever possible. Ten new compounds were evaluated for their anticancer activity against the human breast carcinoma (MCF-7) cell lines in comparison with reference doxorubicin using MTT assay. The results showed that some new compounds have promising anticancer activity.

Two series of novel 1,3,4-thiadiazole-benzofuran and 1,3,4-thiadiazole-furochromene derivatives were synthesized through heterocyclization of alkyl 2-(1-(6-hydroxy-4,7-dimethoxybenzofuran-5-yl)ethylidene)hydrazine-1-carbodithioate 3a–f and 2-(1-(5-methoxy-8-methyl-2,6-dioxo-2,6-dihydropyrano[3,2-g]chromen-3-yl)ethylidene)hydrazinecarbothioamide 9a,b with various hydrazonoyl halides, respectively. The structure of the newly synthesized products was elucidated through elemental analysis, spectral data and alternative routes whenever possible. Ten new compounds were evaluated for their anticancer activity against the human breast carcinoma (MCF-7) cell lines in comparison with reference doxorubicin using MTT assay. The results showed that some new compounds have promising anticancer activity.

Purpose: to identify the genetic variation in two unrelated probands with congenital cataract and to perform functional analysis of the detected variants. Methods: clinical examination and phenotyping, segregation and functional analysis were performed for the two studied pedigrees. Results: a novel OCRL gene variant (c.1964A>T, p. (Asp655Val)) was identified. This variant causes defects in OCRL protein folding and mislocalisation to the cytoplasm. In addition, the variant’s location close to the Rab binding site is likely to be associated with membrane targeting abnormalities. Conclusion: The results highlight the importance of early genetic diagnosis in infants with congenital cataract and show that mutations in the OCRL gene can present as apparently isolated congenital cataract.