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1,4-Benzoxazine skeleton holds substantial promise for further exploration owing to its immense pharmacological potential. In this pursuit, a series of twenty novel benzoxazine based arylidinyl succinimide derivatives (23-42) were synthesized in moderate to good yields by the reaction of ethyl 2-(7-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetate (22) with various aromatic aldehydes under Wittig reaction conditions in the presence of triphenylphosphine and ethanol. All these synthesized compounds were fully characterized from their spectral data (1H, 13C & 2D NMR, IR, UV, HRMS) and further confirmed by X-ray crystallographic analysis of a representative compound (32). Antibacterial activity of obtained arylidinyl succinimide derivatives were evaluated against both Gram-positive and Gram-negative bacterial strains and were found to exhibit insignificant activity as compared to the reference.

In this paper we introduce some strongly summable double sequence spaces defined by a sequence of Orlicz functions over n-normed spaces. We also study some topological properties and inclusion relation between these spaces.

Self-assembly of non-ionic amphiphilic architectures into nanostructures with defined size, shape and morphology has garnered substantial momentum in the recent years due to their extensive applications in biomedicine. The manifestation of a wide range of morphologies such as micelles, vesicles, fibers, tubes, and toroids is thought to be related to the structure of amphiphilic architectures, in particular, the choice of the hydrophilic and hydrophobic parts. In this review, we look at different types of non-ionic small amphiphilic architectures and the factors that influence their self-assembly into various nanostructures in aqueous medium. In particular, we focus on the explored structural parameters that guide the formation of various nanostructures, and the ways these structures can be used in applications ranging from drug delivery to cell imaging.