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SHINTAKU, Y., TAKABAYASHI, T., SASAKI, H., OZAWA, N. and YAJIMA, A. Sister Chramatid Exchanges in Mouse after Exposure to Pulse-Wave Ultrasound in Utero. Tohoku J. Exp. Med., 1993, 170 (2), 63-69 - The induction of sister chromatid exchanges (SCEs) was investigated in mice after a ten in exposure, in vivo, to 2MHz focused, pulse-wave ultrasound with a pulse repetition rate of 1000 Hz, pulse duration of 10μsec. The bone marrow cells of the pregnant female mice and the fetal liver cells were analyzed. The cell cycle specific metaphase patterns were additionally evaluated. In the bone marrow cells, the mean frequencies of SCEs were 2.77 in control, 3.56 in the cells exposed to ultrasound at 586.2 mW/cm2 (spatial average temporal average, SATA); in the fetal liver cells, 2.64 in control, 3.84 in the cells exposed. The frequencies of SCEs significantly were increased by the treatment. Faster cell kinetics was observed in fetal liver cells than bone marrow cells of pregnant female. But there was no cell-growth inhibitory effect of ultrasound on both bone marrow and fetal liver cells. In fetal liver cells, the critical acoustic power was 160.0-278.9mW/cm2 (SATA), - sister chromatid exchange; ultrasound; in vivo

We administered 20 ml of Yomeishu (YMS) twice a day before meals for 12 weeks to 50 post-operative patients in gynecology and then inquired into their subjective 20 symptoms (sense of fatigue, insomnia, headache and heavy headedness, appetite, stomachache, abdominal inflation, vertigo, lumbago, etc.) The YMS group showed a significant improvement on 14 items compared with the control group. On the whole, a great improvement was observed in the YMS group with serious subjective symptoms as well, and there were significant differences for general condition, sense of fatigue, and coldness in extremities.

SOU, S., TAKABAYASHI, T., SASAKI, H., SASAMOTO, K., SHINTAKU, Y., LI, Z.-J., OZAWA, N. and YAJIMA, A. Prenatal Diagnosis of Partial Trisomy 22 Derived from a Maternal t(11; 22) (q23; q11). Tohoku J. exp. Med., 1987, 153 (4), 389-393 - A fetus with partial trisomy 22 was detected by amniocentesis in a pregnant woman with balanced translocation, 46, XX, t(11; 22) (q23; q11). The aborted fetus had multiple congenital anomalies consisting of microcephaly, cleft lip and palate. The extra acrocentric chromosome was identified as der (22), t(11; 22)(q23; q11). The aborted fetus is compared with other trisomic cases described in literatures, and perinatal diagnosis of this case was discussed.

A coldproof reflex horn speaker comprising a frame, a magnet mounted thereto, a diaphragm having a voice coil in its periphery, and inner and outer horns, which is provided with an electric heater device disposed to the outer horn in order to prevent ice and snow from being frozen thereon in cold circumstances.