1. Intravenous Cholangiography in the Rhesus Monkey
- Author
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Teplick Sk, O'brien Jj, Jack Wittenberg, Preblud, Small Dm, Maturi Ra, and Lester F. Williams
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,Double dose ,chemistry.chemical_element ,Intravenous cholangiography ,General Medicine ,Iodine ,Excretion ,Endocrinology ,chemistry ,Concomitant ,Internal medicine ,medicine ,Iodipamide ,Radiology, Nuclear Medicine and imaging ,Inhibitory effect - Abstract
One-hour infusion intravenous cholangiography with iodipamide was performed in 3 rhesus monkeys with intact enterohepatic circulations. A series of four different doses including standard (0.3 ml/kg) and "double dose" (0.6 ml/kg) levels were compared. The 0.6 ml/kg dose resulted in significantly higher biliary iodine excretion and concentration than the lower two doses. A 1.2 ml/kg dose probably increased biliary iodine concentration a small amount when compared to the 0.6 ml/kg dose but did not increase iodine excretion. Peak iodine excretion and concentration occurred, on the average, at one hour. The excretion of iodine in the bile demonstrated no inhibitory effect on the concomitant excretion of bile salts.
- Published
- 1976
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