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We will assess hypothalamic microstructure in children with and without obesity enrolled in the Adolescent Brain Cognitive Development (ABCD) study using diffusion-weighted magnetic resonance imaging technique diffusion basis spectrum imaging (DBSI). Detailed project description and proposed study design are registered here.

Supplemental material, sj-pdf-1-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-2-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-5-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-4-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-2-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-3-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-3-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-5-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal

Supplemental material, sj-pdf-4-msj-10.1177_13524585211023345 for Characterization of multiple sclerosis neuroinflammation and neurodegeneration with relaxation and diffusion basis spectrum imaging by Irene M Vavasour, Peng Sun, Carina Graf, Jackie T Yik, Shannon H Kolind, David KB Li, Roger Tam, Ana-Luiza Sayao, Alice Schabas, Virginia Devonshire, Robert Carruthers, Anthony Traboulsee, GR Wayne Moore, Sheng-Kwei Song and Cornelia Laule in Multiple Sclerosis Journal