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1. Additional file 10: Figure S1. of Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine

Author

Nazleen Lobo, Gedye, Craig, Apostoli, Anthony, Brown, Kevin, Paterson, Joshua, Stickle, Natalie, Robinette, Michael, Fleshner, Neil, Hamilton, Robert, Girish Kulkarni, Zlotta, Alexandre, Evans, Andrew, Finelli, Antonio, Moffat, Jason, Jewett, Michael, and Ailles, Laurie

Subjects
3. Good health
Abstract

Copy number profiles of primary cultures and matched primary tumors and adjacent normal tissues. Figure S2. Morphology of VHLmut vs. VHLwt cultures. Figure S3. VHLwt cells do not express distal tubule markers. Figure S4. Xenografts derived from RCC#243mut and RCC#407mut cultures. Figure S5. Hierarchical clustering heatmap of Pearson correlation coefficients between matched VHLmut cells, VHLwt cells and primary tumor tissues. Figure S6. Functional annotation of 211 VHLmut-associated genes (red) and 382 VHLwt-associated genes. Figure S7. Enrichment map of tumor tissue vs. VHLmut culture gene expression profiles. (PPTX 10688 kb)

2. Additional file 10: Figure S1. of Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine

Author

Nazleen Lobo, Gedye, Craig, Apostoli, Anthony, Brown, Kevin, Paterson, Joshua, Stickle, Natalie, Robinette, Michael, Fleshner, Neil, Hamilton, Robert, Girish Kulkarni, Zlotta, Alexandre, Evans, Andrew, Finelli, Antonio, Moffat, Jason, Jewett, Michael, and Ailles, Laurie

Subjects
3. Good health
Abstract

Copy number profiles of primary cultures and matched primary tumors and adjacent normal tissues. Figure S2. Morphology of VHLmut vs. VHLwt cultures. Figure S3. VHLwt cells do not express distal tubule markers. Figure S4. Xenografts derived from RCC#243mut and RCC#407mut cultures. Figure S5. Hierarchical clustering heatmap of Pearson correlation coefficients between matched VHLmut cells, VHLwt cells and primary tumor tissues. Figure S6. Functional annotation of 211 VHLmut-associated genes (red) and 382 VHLwt-associated genes. Figure S7. Enrichment map of tumor tissue vs. VHLmut culture gene expression profiles. (PPTX 10688 kb)

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