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Introduction Many low resourced low- and middle-income countries (LMICs) do not have access to (high tech) developments in the medical field. The aim of this study is to research how a contemporary high-tech solution, such as customized medical implants, can be transferred to low resource LMICs. Materials and methods We explored the internet to retrieve data regarding internet coverage, services providing free email accounts, and the availability of connecting devices. Additionally, a computerized search was performed for currently available PSI concepts and other important emerging technologies with potential value in craniomaxillofacial surgery. Lastly, we searched the internet for the availability of CT scan devices and smartphones in the LMICs. Results Internet penetration and access to computers/smartphones is low in the LMICs. Moreover, availability of radiology departments and radiologists is very limited (60 radiologists per 190 million Nigerian inhabitants) and a lack of knowledge concerning import regulations and customs clearance, limits the accessibility/availability for patient-specific implants, since this is crucial in developing and delivering these devices. Lastly, appropriate training and instrumentation are vital (yet, currently difficult) to acquire and foresee, in order to achieve the best post-operative results. Conclusion This research confirms great difficulties achieving our aims but with persistence and adoption of well-constructed programs it should be possible.

Introduction Maximizing osteointegration potential of three-dimensionally-printed porous titanium (3DPPT) is an ongoing focus in biomaterial research. Many strategies are proposed and tested but there is no weighted comparison of results. Methods We systematically searched Pubmed and Embase to obtain two pools of 3DPPT studies that performed mechanical implant-removal testing in animal models and whose characteristics were sufficiently similar to compare the outcomes in meta-analyses (MAs). We expanded these MAs to multivariable meta-regressions (moderator analysis) to verify whether statistical models including reported scaffold features (e.g., “pore-size”, “porosity”, “type of unit cell”) or post-printing treatments (e.g., surface treatments, adding agents) could explain the observed differences in treatment effects (expressed as shear strength of bone-titanium interface). Results “Animal type” (species of animal in which the 3DPPT was implanted) and “type of post-treatment” (treatment performed after 3D printing) were moderators providing statistically significant models for differences in mechanical removal strength. An interaction model with covariables “pore-size” and “porosity” in a rabbit subgroup analysis (the most reported animal model) was also significant. Impact of other moderators (including “time” and “location of implant”) was not statistically significant. Discussion/conclusion Our findings suggest a stronger effect from porosity in a rat than in a sheep model. Additionally, adding a calcium-containing layer does not improve removal strength but the other post-treatments do. Our results provide overview and new insights, but little narrowing of existing value ranges. Consequent reporting of 3DPPT characteristics, standardized comparison, and expression of porosity in terms of surface roughness could help tackle these existing dilemmas. Graphical abstract

Background Various studies have investigated the load-bearing capacity of patient-specific cranial implants. However, little attention has been given to the evaluation of the design of ceramic-titanium (CeTi) implants. Methods A biomechanical evaluation of 3 patient-specific cranial implants was performed using finite element analysis. Results The results of the analyses allowed the identification of the implant regions as well as the magnitudes of the maximum stresses on, and displacements along, these regions after traumatic impact. The analyses also showed that polyether ether ketone cranial implants offer inferior brain and neurocranial protection due to their high flexibility and local peak stresses at the bone-screw interface. In contrast, CeTi implants were able to evenly distribute the stresses along the interface and thus reduced the risk of neurocranial fracture. The scaffold structure at the border of these implants reduced stress shielding and enhanced bone ingrowth. Moreover, brain injuries were less likely to occur, as the CeTi implant exhibits limited deflection. Conclusions From the finite element analyses, CeTi cranial implants appear less likely to induce calvarial fractures with a better potential to protect the brain under impact loads.

Study Design: Technical note. Objective: Computer-aided design and computer-aided manufacturing (CADCAM) is commonly used in craniomaxillofacial (CMF) surgery because of its advantage in customizing medical devices. We used this technology to create individualized, resin-bonded 3-dimensionally printed titanium arch bars. Method: This article describes a patient specific, three-dimensionally (3D) printed, resin-bonded arch bar as an alternative to the classical intermaxillary fixation systems. Results: The ease of application and removal, as well as the protection of the periodontal and cheek tissues, and operator fingers, made this a comfortable technique for both the patient and practitioner. Conclusions: A patient-specific 3D-printed titanium arch bar can be useful in the arsenal of the maxillofacial surgeon.